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CAS 2061-64-5 may appear across multiple EU annex records. The CAS lookup page shows all Annex II–VI entries sharing this identifier, useful for identifying cross-annex regulatory status of the same chemical substance.

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InventoryRef 8263015/10/2010

ERGOSTEROL ENDOPEROXIDE

Ergosterol-5,8-peroxide

ERGOSTEROL ENDOPEROXIDE is listed in the EU CosIng inventory, but no direct annex records are linked on this page yet.

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Regulatory evidence by market

No rule for this ingredient has been imported for any of the 13 markets tracked here.

That describes this inventory, not the law. No imported rule is not evidence that an ingredient is permitted: a rule may exist under another name or identifier, or in a dataset not yet imported here.

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Chemical identity and properties

PubChem 2D chemical structure for CAS 2061-64-5

CAS 2061-64-5PubChem CID 5351516

Ergosterol Peroxide

Ergosterol peroxide is an ergostanoid that is ergosta-6,22-dien-3-ol with a peroxy group between positions 5 and 8 (the 3beta,5alpha,8alpha,22E stereoisomer). Isolated from Ganoderma lucidum and Cordyceps sinensis, it exhibits antimycobacterial, trypanocidal and antineoplastic activities. It has a role as a metabolite, an antineoplastic agent, a trypanocidal drug and an antimycobacterial drug. It is an organic peroxide, a member of phytosterols, a 3beta-sterol and an ergostanoid. It is functionally related to an ergosterol. — ChEBI

IUPAC name: (1S,2R,5R,6R,9R,10R,13S,15S)-5-[(E,2R,5R)-5,6-dimethylhept-3-en-2-yl]-6,10-dimethyl-16,17-dioxapentacyclo[13.2.2.01,9.02,6.010,15]nonadec-18-en-13-ol

Molecular formula: C28H44O3
Molecular weight: 428.6 g/mol
Exact mass: 428.32904526 Da
XLogP3: 6.7
Topological polar surface area: 38.7 Å²
Hydrogen-bond donors: 1
Hydrogen-bond acceptors: 3
Covalent units: 1
Defined stereocentres: 10

Also known as

Ergosterol endoperoxidePeroxyergosterolErgosterol-5,8-peroxideErgosterol 5alpha,8alpha-epidioxideUG9TN81TGHNSC-31324CHEBI:65858(22E,24R)-5alpha,8alpha-epidioxyergosta-6,22-dien-3beta-ol

16 more reported names

3-hydroxy-5,7-epidioxyergosta-6,22-diene5alpha,8alpha-Ergosta-6,22-dien-3beta-ol, 5,8-epidioxy-Ergosta-6,22-dien-3-ol, 5,8-epidioxy-, (3beta,5alpha,8alpha,22E)-(1S,2R,5R,6R,9R,10R,13S,15S)-5-((E,2R,5R)-5,6-dimethylhept-3-en-2-yl)-6,10-dimethyl-16,17-dioxapentacyclo(13.2.2.01,9.02,6.010,15)nonadec-18-en-13-ol5,8-epidioxyergosta-6,22-dien-3-olRefChem:9211085alpha,8alpha-epidioxy-22E-ergosta-6,22-dien-3beta-ol(24R)-5alpha,8alpha-epidioxy-24-methylcholesta-6,22-dien-3beta-olNSC 31324(1S,2R,5R,6R,9R,10R,13S,15S)-5-[(2R,3E,5R)-5,6-dimethylhept-3-en-2-yl]-6,10-dimethyl-16,17-dioxapentacyclo[13.2.2.0^{1,9}.0^{2,6}.0^{10,15}]nonadec-18-en-13-olUNII-UG9TN81TGH(3beta,5alpha,8alpha,22E)-5,8-epidioxyergosta-6,22-dien-3-ol5.alpha.,8.alpha.-Ergosta-6,22-dien-3.beta.-ol, 5,8-epidioxy-Ergosta-6,22-dien-3-ol, 5,8-epidioxy-, (3.beta.,5.alpha.,8.alpha.,22E)-Ergosterol 5.alpha.,8.alpha.-epidioxideErgosterol 5-alpha,8-alpha-epidioxide

Open full PubChem record PubChem annotations 3D structure image

External database identifiers

ChEBI:CHEBI:65858
ChEMBL:CHEMBL434750
EPA DTXSID:DTXSID501021533
PubMed:20100469
PubMed:20085279
PubMed:19475991
PubMed:16595913

Retrieved from NIH PubChem on 2026-08-31 by checksum-valid CAS matching. Chemical properties do not replace the regulatory decision on this page.

Inventory details for ERGOSTEROL ENDOPEROXIDE

INCI name

ERGOSTEROL ENDOPEROXIDE

Description

Ergosterol-5,8-peroxide

Record provenance

Inventory reference: 82630
Imported identity: ERGOSTEROL ENDOPEROXIDE
Source update: 15/10/2010

European Commission CosIng source notes

Annex records for ERGOSTEROL ENDOPEROXIDE

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Key data

CAS

2061-64-5

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Restriction

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Function

BLEACHING: Bleaching or lightening the shade of hair and/or skin.
HUMECTANT: Retaining and/or preserving the moisture in a product during use.
SKIN CONDITIONING: Maintaining the skin in good condition.

Official EU ingredient-name evidence

The ingredient name exactly matches the official 2025 EU glossary of common ingredient names.

#9916 · ERGOSTEROL ENDOPEROXIDE

Ingredients with overlapping formulation functions

DOCOSAHEXENOIC/DOCOSAPENTENOIC/OLEIC/PALMITIC TRIGLYCERIDEBLEACHING, SKIN CONDITIONING, SKIN PROTECTING

DRACOCEPHALUM RUYSCHIANA CALLUS EXTRACTANTIOXIDANT, BLEACHING, SKIN PROTECTING

ENKLEIA THORELII ROOT EXTRACTANTIOXIDANT, BLEACHING, SKIN CONDITIONING

ENTEROMORPHA PROLIFERA EXTRACTBLEACHING; SKIN PROTECTING; SKIN CONDITIONING - HUMECTANT

ERIOBOTRYA JAPONICA SEED EXTRACTBLEACHING, SKIN CONDITIONING

ETHYL SALICYLATE HEXYL ETHERBLEACHING

EXCOECARIA BICOLOR LEAF EXTRACTANTIOXIDANT, BLEACHING

EXTRUDED HUMAN ADIPOSE DERIVED STEM CELLSBLEACHING; SKIN CONDITIONING - MISCELLANEOUS

Additional official and scientific sources

11 external databases to check this identity in

Each link searches that source for this identity. What each source is, and its legal weight

ECHA CHEM / Information on chemicals PubChem PUG REST EU Safety Gate cosmetic product alerts ECHA CHEM US EPA CompTox Cosmetic Ingredient Review safety assessments FDA Global Substance Registration System ILO/WHO International Chemical Safety Cards Japan NITE-CHRIP NIOSH Pocket Guide to Chemical Hazards OECD eChemPortal

How ERGOSTEROL ENDOPEROXIDE appears in the CosIng inventory

The CosIng inventory lists ERGOSTEROL ENDOPEROXIDE as a cosmetic ingredient and this page links it to 0 annex records. The inventory entry captures names and identifiers, while the annex records show where the substance is prohibited, restricted or positively listed in EU cosmetics law.

ERGOSTEROL ENDOPEROXIDE is also tagged with 3 cosmetic functions in the official data. Function labels describe intended use, but they do not replace regulatory review of linked annex records before formulation or labelling work.

Frequently asked questions

ERGOSTEROL ENDOPEROXIDE is listed in the EU CosIng ingredient inventory with no direct annex restriction records linked at this time. Absence of an annex link does not guarantee unrestricted use — always verify against the current official CosIng database before formulating.

According to the EU CosIng inventory, ERGOSTEROL ENDOPEROXIDE carries the following function designation(s):

CAS 2061-64-5 may appear across multiple EU annex records. Viewing the CAS lookup page shows all Annex II–VI entries sharing this identifier, which is useful for identifying cross-annex regulatory status of the same chemical substance.

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Source note for ERGOSTEROL ENDOPEROXIDE

This page reproduces the CosIng inventory entry for ERGOSTEROL ENDOPEROXIDE from public European Commission cosmetic ingredient materials and shows linked identifiers even when no direct annex match is currently attached.

Use this inventory page to research ERGOSTEROL ENDOPEROXIDE and compare linked records, but verify restrictions and legal status against the current official source text and law before making regulatory decisions.

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