Is THYMIDINE safe to use in EU cosmetics?

THYMIDINE is listed in the EU CosIng ingredient inventory with no direct annex restriction records linked at this time. Always verify against the current official CosIng database before formulating.

What other records share CAS 50-89-5?

CAS 50-89-5 may appear across multiple EU annex records. The CAS lookup page shows all Annex II–VI entries sharing this identifier, useful for identifying cross-annex regulatory status of the same chemical substance.

How do I check if my formula contains THYMIDINE?

Use the INCI Checker to screen a full ingredient list across selected markets, or use the substance market comparison to review this identity across all supported market datasets.

InventoryRef 8243415/10/2010

THYMIDINE

2'-Deoxythymidine

THYMIDINE is listed in the EU CosIng inventory, but no direct annex records are linked on this page yet.

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Regulatory evidence by market

No rule for this ingredient has been imported for any of the 13 markets tracked here.

That describes this inventory, not the law. No imported rule is not evidence that an ingredient is permitted: a rule may exist under another name or identifier, or in a dataset not yet imported here.

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Chemical identity and properties

PubChem 2D chemical structure for CAS 50-89-5

CAS 50-89-5PubChem CID 5789

Thymidine

Thymidine is a pyrimidine 2'-deoxyribonucleoside having thymine as the nucleobase. It has a role as a metabolite, a mouse metabolite, an Escherichia coli metabolite and a human metabolite. It is functionally related to a thymine. It is an enantiomer of a telbivudine. — ChEBI

IUPAC name: 1-[(2R,4S,5R)-4-hydroxy-5-(hydroxymethyl)oxolan-2-yl]-5-methylpyrimidine-2,4-dione

Molecular formula: C10H14N2O5
Molecular weight: 242.23 g/mol
Exact mass: 242.09027155 Da
XLogP3: -1.2
Topological polar surface area: 99.1 Å²
Hydrogen-bond donors: 3
Hydrogen-bond acceptors: 5
Covalent units: 1
Defined stereocentres: 3

Also known as

2'-DeoxythymidineDThydThymidinThymine-2-desoxyriboside5-Methyl-2'-deoxyuridineThyminedeoxyribosideDeoxyribothymidineDoxribtimine

16 more reported names

dThd2'-thymidine1-[(2R,4S,5R)-4-hydroxy-5-(hydroxymethyl)oxolan-2-yl]-5-methyl-1,2,3,4-tetrahydropyrimidine-2,4-dionethymine 2'-deoxyribosideVC2W18DGKR2'-deoxy-5-methyluridineCHEBI:17748NSC-21548MT-1621 COMPONENT 2'-DEOXYTHYMIDINE1-(2-deoxy-beta-D-erythro-pentofuranosyl)-5-methylpyrimidine-2,4(1H,3H)-dione2' Deoxythymidine1-((2R,4S,5R)-4-hydroxy-5-(hydroxymethyl)oxolan-2-yl)-5-methylpyrimidine-2,4-dione1-((2R,4S,5R)-4-hydroxy-5-(hydroxymethyl)oxolan-2-yl)-5-methyl-1,2,3,4-tetrahydropyrimidine-2,4-dioneRefChem:189836200-070-4deoxythymidine

Open full PubChem record PubChem annotations 3D structure image

External database identifiers

ChEBI:CHEBI:17748
ChEMBL:CHEMBL52609
EPA DTXSID:DTXSID5023661
PubMed:37726507
PubMed:37700034
PubMed:37183367
PubMed:31939704
PubMed:31170432
PubMed:26340795
PubMed:25847167
PubMed:24872885
PubMed:24647036
PubMed:22882409
PubMed:22764600
PubMed:22753710

Retrieved from NIH PubChem on 2026-08-31 by checksum-valid CAS matching. Chemical properties do not replace the regulatory decision on this page.

Inventory details for THYMIDINE

INCI name

THYMIDINE

Description

2'-Deoxythymidine

Record provenance

Inventory reference: 82434
Imported identity: THYMIDINE
Source update: 15/10/2010

European Commission CosIng source notes

Annex records for THYMIDINE

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Key data

CAS

50-89-5

200-070-4

Restriction

—

Function

SKIN CONDITIONING: Maintaining the skin in good condition.

Official EU ingredient-name evidence

The ingredient name exactly matches the official 2025 EU glossary of common ingredient names.

#28809 · THYMIDINE

Ingredients with overlapping formulation functions

THUJOPSIS DOLABRATA BRANCH EXTRACTSKIN CONDITIONING

THUNBERGIA LAURIFOLIA LEAF EXTRACTSKIN CONDITIONING

THURFYL NICOTINATESKIN CONDITIONING

THURFYLNICOTINATE HCLSKIN CONDITIONING

THYMINESKIN CONDITIONING

THYMUS EXTRACTSKIN CONDITIONING

THYMUS HYDROLYSATEHUMECTANT, SKIN CONDITIONING

THYMUS LINEARIS LEAF EXTRACTSKIN CONDITIONING

Additional official and scientific sources

11 external databases to check this identity in

Each link searches that source for this identity. What each source is, and its legal weight

ECHA CHEM / Information on chemicals PubChem PUG REST EU Safety Gate cosmetic product alerts ECHA CHEM US EPA CompTox Cosmetic Ingredient Review safety assessments FDA Global Substance Registration System ILO/WHO International Chemical Safety Cards Japan NITE-CHRIP NIOSH Pocket Guide to Chemical Hazards OECD eChemPortal

How THYMIDINE appears in the CosIng inventory

The CosIng inventory lists THYMIDINE as a cosmetic ingredient and this page links it to 0 annex records. The inventory entry captures names and identifiers, while the annex records show where the substance is prohibited, restricted or positively listed in EU cosmetics law.

THYMIDINE is also tagged with 1 cosmetic function in the official data. Function labels describe intended use, but they do not replace regulatory review of linked annex records before formulation or labelling work.

Frequently asked questions

THYMIDINE is listed in the EU CosIng ingredient inventory with no direct annex restriction records linked at this time. Absence of an annex link does not guarantee unrestricted use — always verify against the current official CosIng database before formulating.

According to the EU CosIng inventory, THYMIDINE carries the following function designation(s):

SKIN CONDITIONING

CAS 50-89-5 may appear across multiple EU annex records. Viewing the CAS lookup page shows all Annex II–VI entries sharing this identifier, which is useful for identifying cross-annex regulatory status of the same chemical substance.

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Source note for THYMIDINE

This page reproduces the CosIng inventory entry for THYMIDINE from public European Commission cosmetic ingredient materials and shows linked identifiers even when no direct annex match is currently attached.

Use this inventory page to research THYMIDINE and compare linked records, but verify restrictions and legal status against the current official source text and law before making regulatory decisions.

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Tools & next steps

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