What does the restriction note for ZINC CITRATE mean?

The restriction field for ZINC CITRATE reads: III/24. This is the restriction note from the CosIng inventory. For authoritative conditions and limits, always refer to the linked annex entries.

What other records share CAS 546-46-3?

CAS 546-46-3 may appear across multiple EU annex records. The CAS lookup page shows all Annex II–VI entries sharing this identifier, useful for identifying cross-annex regulatory status of the same chemical substance.

How do I check if my formula contains ZINC CITRATE?

Use the INCI Checker to screen a full ingredient list across selected markets, or use the substance market comparison to review this identity across all supported market datasets.

InventoryRef 8074815/10/2010

ZINC CITRATE

Q: Is ZINC CITRATE safe to use in EU cosmetics?

ZINC CITRATE appears in the EU CosIng inventory and has linked annex records. Check the annex records for applicable restrictions, concentration limits and conditions of use. Annex II means prohibited; Annex III means restricted; Annexes IV, V and VI mean permitted under specified conditions.

Q: What function does ZINC CITRATE serve in cosmetics?

According to the EU CosIng inventory, ZINC CITRATE carries the following function designation(s): ANTIPLAQUE, ORAL CARE.

Trizinc dicitrate

ZINC CITRATE is linked to 1 EU annex record on this page. Inventory note: III/24.

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Regulatory evidence by market

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Market	Evidence status	Records	Source language
European Union	Evidence linked Restricted entry found Open this evidence	1	English and EU languages
Great Britain	Source mapped Official source mapped; ingredient rule not imported	0	English
Canada	Source mapped Official source mapped; ingredient rule not imported	0	English and French
New Zealand	Source mapped Official source mapped; ingredient rule not imported	0	English
ASEAN	Source mapped Official source mapped; ingredient rule not imported	0	English and national languages
China	Source mapped Official source mapped; ingredient rule not imported	0	Chinese with selected English material
Japan	Source mapped Official source mapped; ingredient rule not imported	0	Japanese; official English translation available
South Korea	Source mapped Official source mapped; ingredient rule not imported	0	Korean with some English names
United States	Source mapped Official source mapped; ingredient rule not imported	0	English
Australia	Source mapped Official source mapped; ingredient rule not imported	0	English
Brazil	Source mapped Official source mapped; ingredient rule not imported	0	Portuguese with INCI crosswalks
India	Source mapped Official source mapped; ingredient rule not imported	0	English and Hindi
Saudi Arabia	Source mapped Official source mapped; ingredient rule not imported	0	Arabic and English

Chemical identity and properties

PubChem 2D chemical structure for CAS 546-46-3

CAS 546-46-3PubChem CID 11023

Zinc Citrate

Zinc citrate is a zinc salt of citric acid. It is available as dietary supplements as a treatment of zinc deficiency and source of zinc, which is an essential trace element. Zinc citrate demonstrates effective absorption following oral administration. — DrugBank

IUPAC name: trizinc bis(2-hydroxypropane-1,2,3-tricarboxylate)

Molecular formula: C12H10O14Zn3
Molecular weight: 574.3 g/mol
Exact mass: 571.79137 Da
Topological polar surface area: 281.0 Å²
Hydrogen-bond donors: 2
Hydrogen-bond acceptors: 14
Covalent units: 5
Defined stereocentres: 0

Also known as

K72I3DEX9BCITRATED ZINC2-Hydroxy-1,2,3-propanetricarboxylic acid zinc saltZINC CITRATE (MART.)ZINC CITRATE [MART.]RefChem:6361208-901-2Trizinc dicitrate

16 more reported names

Citric acid, zinc salt1,2,3-Propanetricarboxylic acid, 2-hydroxy-, zinc salt (2:3)trizinc;2-hydroxypropane-1,2,3-tricarboxylate2-Hydroxy-1,2,3-propanetricarboxylic acid zinc salt (2:3)EINECS 208-901-2UNII-K72I3DEX9BCITRIC ACID, ZINC SALT (2:3)ZINC CITRATE [MI]EC 208-901-2CITRATED ZINC [VANDF]ZINC CITRATE [WHO-DD]2-Hydroxy-1,2,3-propanetricarboxylic acid, zinc salt5590-32-9Zinc 2-hydroxypropane-1,2,3-tricarboxylate (3/2)Zinc citarte dihydrate, Ultra pure, USP, Fine granular, Low heavy metals (As: <= 1 ppm, Cd: <= 1 ppm, Pb: <= 5 ppm & Hg: <= 0.1 ppm)Zinc citarte dihydrate, Ultra pure, USP, Powder, Low heavy metals (As: <= 1 ppm, Cd: <= 1 ppm, Pb: <= 5 ppm & Hg: <= 0.1 ppm)

Open full PubChem record PubChem annotations 3D structure image

External database identifiers

EPA DTXSID:DTXSID90889427
PubMed:24259556

Retrieved from NIH PubChem on 2026-08-31 by checksum-valid CAS matching. Chemical properties do not replace the regulatory decision on this page.

Inventory details for ZINC CITRATE

INCI name

ZINC CITRATE

Description

Trizinc dicitrate

Record provenance

Inventory reference: 80748
Imported identity: ZINC CITRATE
Source update: 15/10/2010

European Commission CosIng source notes

Annex records for ZINC CITRATE

Annex III Restriction reference

Entry 24

ZINC ACETATE / ZINC CHLORIDE / ZINC GLUCONATE / ZINC GLUTAMATE

Key data

CAS

546-46-3

208-901-2

Restriction

III/24

Function

ANTIPLAQUE: Helping protect against plaque.
ORAL CARE: Providing cosmetic effects to the oral cavity, e.g. cleansing, deodorising, protecting.

Official EU ingredient-name evidence

The ingredient name exactly matches the official 2025 EU glossary of common ingredient names.

#30298 · ZINC CITRATE

Ingredients with overlapping formulation functions

TRIPEPTIDE-62ANTIOXIDANT, ANTIPLAQUE, ORAL CARE, SKIN PROTECTING

TRIPEPTIDE-66ANTIOXIDANT, ANTIPLAQUE, HAIR CONDITIONING, NAIL CONDITIONING, SKIN PROTECTING

TRIPEPTIDE-67ANTIOXIDANT, ANTIPLAQUE, SKIN CONDITIONING, SKIN PROTECTING

WATERANTIPLAQUE, SKIN CONDITIONING, SOLVENT

ZINC PHOSPHATEANTIPLAQUE

ZINC SULFATEANTIMICROBIAL, ANTIPLAQUE, ASTRINGENT, ORAL CARE

ZINC/STRONTIUM FLUORIDE HYDROXYAPATITEANTIPLAQUE

Additional official and scientific sources

11 external databases to check this identity in

Each link searches that source for this identity. What each source is, and its legal weight

ECHA CHEM / Information on chemicals PubChem PUG REST EU Safety Gate cosmetic product alerts ECHA CHEM US EPA CompTox Cosmetic Ingredient Review safety assessments FDA Global Substance Registration System ILO/WHO International Chemical Safety Cards Japan NITE-CHRIP NIOSH Pocket Guide to Chemical Hazards OECD eChemPortal

How ZINC CITRATE appears in the CosIng inventory

The CosIng inventory lists ZINC CITRATE as a cosmetic ingredient and this page links it to 1 annex record. The inventory entry captures names and identifiers, while the annex record shows where the substance is prohibited, restricted or positively listed in EU cosmetics law.

ZINC CITRATE is also tagged with 2 cosmetic functions in the official data. Function labels describe intended use, but they do not replace regulatory review of linked annex records before formulation or labelling work.

Frequently asked questions

ZINC CITRATE appears in the EU CosIng inventory and has linked annex records. Check the annex records above for applicable restrictions, concentration limits and conditions of use. Annex II listing means prohibited; Annex III means restricted; Annexes IV, V and VI mean permitted under specified conditions.

The restriction field for ZINC CITRATE reads: "III/24". This is the restriction note recorded in the CosIng inventory for this ingredient. For authoritative conditions and limits, always refer to the linked annex entries above.

According to the EU CosIng inventory, ZINC CITRATE carries the following function designation(s):

CAS 546-46-3 may appear across multiple EU annex records. Viewing the CAS lookup page shows all Annex II–VI entries sharing this identifier, which is useful for identifying cross-annex regulatory status of the same chemical substance.

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Source note for ZINC CITRATE

This page combines the CosIng inventory entry for ZINC CITRATE with 1 linked Annex II–VI record from the local dataset built from public European Commission cosmetic ingredient materials.

Use this inventory page to research ZINC CITRATE and compare linked records, but verify restrictions and legal status against the current official source text and law before making regulatory decisions.

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Tools & next steps

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