Is POLOXAMER 403 safe to use in EU cosmetics?

POLOXAMER 403 is listed in the EU CosIng ingredient inventory with no direct annex restriction records linked at this time. Always verify against the current official CosIng database before formulating.

What other records share CAS 9003-11-6?

CAS 9003-11-6 may appear across multiple EU annex records. The CAS lookup page shows all Annex II–VI entries sharing this identifier, useful for identifying cross-annex regulatory status of the same chemical substance.

How do I check if my formula contains POLOXAMER 403?

Use the INCI Checker to screen a full ingredient list across selected markets, or use the substance market comparison to review this identity across all supported market datasets.

InventoryRef 8015415/10/2010

POLOXAMER 403

Oxirane, methyl-, polymer with oxirane (21;67)

POLOXAMER 403 is listed in the EU CosIng inventory, but no direct annex records are linked on this page yet.

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Regulatory evidence by market

No rule for this ingredient has been imported for any of the 13 markets tracked here.

That describes this inventory, not the law. No imported rule is not evidence that an ingredient is permitted: a rule may exist under another name or identifier, or in a dataset not yet imported here.

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Exact external identity check

not_found

No complete-name PubChem match was verified. The material may be a mixture, trade-style INCI identity or be indexed under another identifier; this result must not be read as proof that no related chemistry exists.

Exact CosIng INCI name equals a PubChem synonym · Checked 2026-08-31

Inventory details for POLOXAMER 403

INCI name

POLOXAMER 403

Description

Oxirane, methyl-, polymer with oxirane (21;67)

Record provenance

Inventory reference: 80154
Imported identity: POLOXAMER 403
Source update: 15/10/2010

European Commission CosIng source notes

Annex records for POLOXAMER 403

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Key data

CAS

9003-11-6

—

Restriction

—

Function

SURFACTANT - CLEANSING: Wetting body surfaces, emulsifying or solubilizing oils, and suspending soil (generally, such ingredients contribute to the foaming and lathering properties of cleansing products).
SURFACTANT - EMULSIFYING: Helping suspensions or dispersions of liquids in a second liquid by reducing the surface tension of the substances to be emulsified.

Official EU ingredient-name evidence

The ingredient name exactly matches the official 2025 EU glossary of common ingredient names.

#21458 · POLOXAMER 403

Records sharing a CAS or EC identity

MEROXAPOL 105 MEROXAPOL 108 MEROXAPOL 171 MEROXAPOL 172 MEROXAPOL 174 MEROXAPOL 178 MEROXAPOL 251 MEROXAPOL 252

Ingredients with overlapping formulation functions

POLOXAMER 335SURFACTANT - CLEANSING, SURFACTANT - EMULSIFYING

POLOXAMER 338SURFACTANT - CLEANSING, SURFACTANT - EMULSIFYING

POLOXAMER 401SURFACTANT - CLEANSING, SURFACTANT - EMULSIFYING

POLOXAMER 402SURFACTANT - CLEANSING, SURFACTANT - EMULSIFYING

POLOXAMER 407SURFACTANT - CLEANSING, SURFACTANT - EMULSIFYING

POLOXAMINE 1101SURFACTANT - EMULSIFYING

POLOXAMINE 1102SURFACTANT - EMULSIFYING

POLOXAMINE 1104SURFACTANT - EMULSIFYING

Additional official and scientific sources

11 external databases to check this identity in

Each link searches that source for this identity. What each source is, and its legal weight

ECHA CHEM / Information on chemicals PubChem PUG REST EU Safety Gate cosmetic product alerts ECHA CHEM US EPA CompTox Cosmetic Ingredient Review safety assessments FDA Global Substance Registration System ILO/WHO International Chemical Safety Cards Japan NITE-CHRIP NIOSH Pocket Guide to Chemical Hazards OECD eChemPortal

How POLOXAMER 403 appears in the CosIng inventory

The CosIng inventory lists POLOXAMER 403 as a cosmetic ingredient and this page links it to 0 annex records. The inventory entry captures names and identifiers, while the annex records show where the substance is prohibited, restricted or positively listed in EU cosmetics law.

POLOXAMER 403 is also tagged with 2 cosmetic functions in the official data. Function labels describe intended use, but they do not replace regulatory review of linked annex records before formulation or labelling work.

Frequently asked questions

POLOXAMER 403 is listed in the EU CosIng ingredient inventory with no direct annex restriction records linked at this time. Absence of an annex link does not guarantee unrestricted use — always verify against the current official CosIng database before formulating.

According to the EU CosIng inventory, POLOXAMER 403 carries the following function designation(s):

CAS 9003-11-6 may appear across multiple EU annex records. Viewing the CAS lookup page shows all Annex II–VI entries sharing this identifier, which is useful for identifying cross-annex regulatory status of the same chemical substance.

View CAS records

Use the INCI Checker to screen a full ingredient list across selected markets, or compare this substance across all supported market datasets.

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Source note for POLOXAMER 403

This page reproduces the CosIng inventory entry for POLOXAMER 403 from public European Commission cosmetic ingredient materials and shows linked identifiers even when no direct annex match is currently attached.

Use this inventory page to research POLOXAMER 403 and compare linked records, but verify restrictions and legal status against the current official source text and law before making regulatory decisions.

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Tools & next steps

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