Is SODIUM PCA safe to use in EU cosmetics?

SODIUM PCA is listed in the EU CosIng ingredient inventory with no direct annex restriction records linked at this time. Always verify against the current official CosIng database before formulating.

What function does SODIUM PCA serve in cosmetics?

According to the EU CosIng inventory, SODIUM PCA carries the following function designation(s): ANTISTATIC, HAIR CONDITIONING, HUMECTANT, SKIN CONDITIONING.

What other records share CAS 28874-51-3?

CAS 28874-51-3 may appear across multiple EU annex records. The CAS lookup page shows all Annex II–VI entries sharing this identifier, useful for identifying cross-annex regulatory status of the same chemical substance.

How do I check if my formula contains SODIUM PCA?

Use the INCI Checker to screen a full ingredient list across selected markets, or use the substance market comparison to review this identity across all supported market datasets.

InventoryRef 7991015/10/2010

SODIUM PCA

Sodium 5-oxo-2-pyrrolidinecarboxylate

SODIUM PCA is listed in the EU CosIng inventory, but no direct annex records are linked on this page yet.

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Regulatory evidence by market

No rule for this ingredient has been imported for any of the 13 markets tracked here.

That describes this inventory, not the law. No imported rule is not evidence that an ingredient is permitted: a rule may exist under another name or identifier, or in a dataset not yet imported here.

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Chemical identity and properties

PubChem 2D chemical structure for CAS 28874-51-3

CAS 28874-51-3PubChem CID 23668602

Sodium Pidolate

IUPAC name: sodium (2S)-5-oxopyrrolidine-2-carboxylate

Molecular formula: C5H6NNaO3
Molecular weight: 151.10 g/mol
Exact mass: 151.02453734 Da
Topological polar surface area: 69.2 Å²
Hydrogen-bond donors: 1
Hydrogen-bond acceptors: 3
Covalent units: 2
Defined stereocentres: 1

Also known as

Sodium L-pyroglutamateSodium pyroglutamateL-Proline, 5-oxo-, monosodium saltL-5-Oxoproline monosodium saltSodium pyrrolidone-5-carboxylate5-Oxo-L-proline monosodium saltSodium L-pyrrolidonecarboxylateEINECS 249-277-1

16 more reported names

UNII-1V74VH163TProline, 5-oxo-, monosodium salt, L-PDSI 1011V74VH163TL-SODIUM PIDOLATESODIUM PIDOLATE [WHO-DD]EC 249-277-1Pidolate SodiumRefChem:184083249-277-12-Pyrrolidone-5-Carboxylic Acid Sodium SaltSodium 5-oxo-L-prolinateProline, 5-oxo-, monosodium saltSodium (S)-5-oxopyrrolidine-2-carboxylateSodium L-Pyroglutamate (Technical Grade)sodium;(2S)-5-oxopyrrolidine-2-carboxylate

Open full PubChem record PubChem annotations 3D structure image

External database identifiers

EPA DTXSID:DTXSID50183074

Retrieved from NIH PubChem on 2026-08-31 by checksum-valid CAS matching. Chemical properties do not replace the regulatory decision on this page.

Inventory details for SODIUM PCA

INCI name

SODIUM PCA

Description

Sodium 5-oxo-2-pyrrolidinecarboxylate

Record provenance

Inventory reference: 79910
Imported identity: SODIUM PCA
Source update: 15/10/2010

European Commission CosIng source notes

Annex records for SODIUM PCA

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Key data

CAS

28874-51-3

249-277-1

Restriction

—

Function

ANTISTATIC: Preventing and/or reducing static electricity by neutralising electrical charge on surfaces.
HAIR CONDITIONING: Enhancing the appearance and feel of hair. Leaving the hair easy to comb, supple, soft and shiny and/or imparting volume, lightness, gloss, texture, etc.
HUMECTANT: Retaining and/or preserving the moisture in a product during use.
SKIN CONDITIONING: Maintaining the skin in good condition.

Official EU ingredient-name evidence

The ingredient name exactly matches the official 2025 EU glossary of common ingredient names.

#26898 · SODIUM PCA

Ingredients with overlapping formulation functions

SODIUM OLEOYL HYDROLYZED COLLAGENANTISTATIC, CLEANSING, HAIR CONDITIONING, SKIN CONDITIONING, SURFACTANT - CLEANSING

SODIUM OLEOYL ISETHIONATEANTISTATIC, CLEANSING, FOAMING, HAIR CONDITIONING, SURFACTANT - CLEANSING

SODIUM OLIVAMIDOPROPYL PG-DIMONIUM CHLORIDE PHOSPHATEANTISTATIC, HAIR CONDITIONING

SODIUM PALM KERNELAMPHOPROPIONATEANTISTATIC, CLEANSING, FOAMING, HAIR CONDITIONING

SODIUM PEG-4 LAURAMIDE SULFATEANTISTATIC, CLEANSING, FOAMING, HAIR CONDITIONING

SODIUM SILVER MERCAPTOBENZIMIDAZOLE SULFONATEANTISTATIC, DEODORANT, SKIN CONDITIONING, SURFACTANT - CLEANSING

SODIUM SOY HYDROLYZED COLLAGENANTISTATIC, HAIR CONDITIONING, SURFACTANT - CLEANSING

SODIUM STEAROAMPHOACETATEANTISTATIC, CLEANSING, FOAMING, HAIR CONDITIONING, SURFACTANT - CLEANSING, SURFACTANT - FOAM BOOSTI…

Additional official and scientific sources

11 external databases to check this identity in

Each link searches that source for this identity. What each source is, and its legal weight

ECHA CHEM / Information on chemicals PubChem PUG REST EU Safety Gate cosmetic product alerts ECHA CHEM US EPA CompTox Cosmetic Ingredient Review safety assessments FDA Global Substance Registration System ILO/WHO International Chemical Safety Cards Japan NITE-CHRIP NIOSH Pocket Guide to Chemical Hazards OECD eChemPortal

How SODIUM PCA appears in the CosIng inventory

The CosIng inventory lists SODIUM PCA as a cosmetic ingredient and this page links it to 0 annex records. The inventory entry captures names and identifiers, while the annex records show where the substance is prohibited, restricted or positively listed in EU cosmetics law.

SODIUM PCA is also tagged with 4 cosmetic functions in the official data. Function labels describe intended use, but they do not replace regulatory review of linked annex records before formulation or labelling work.

Frequently asked questions

SODIUM PCA is listed in the EU CosIng ingredient inventory with no direct annex restriction records linked at this time. Absence of an annex link does not guarantee unrestricted use — always verify against the current official CosIng database before formulating.

According to the EU CosIng inventory, SODIUM PCA carries the following function designation(s):

CAS 28874-51-3 may appear across multiple EU annex records. Viewing the CAS lookup page shows all Annex II–VI entries sharing this identifier, which is useful for identifying cross-annex regulatory status of the same chemical substance.

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Use the INCI Checker to screen a full ingredient list across selected markets, or compare this substance across all supported market datasets.

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Source note for SODIUM PCA

This page reproduces the CosIng inventory entry for SODIUM PCA from public European Commission cosmetic ingredient materials and shows linked identifiers even when no direct annex match is currently attached.

Use this inventory page to research SODIUM PCA and compare linked records, but verify restrictions and legal status against the current official source text and law before making regulatory decisions.

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Tools & next steps

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