What does the restriction note for PIGMENT RED 57:1 mean?

The restriction field for PIGMENT RED 57:1 reads: III/296 (Pigment Red 57) IV/27 (CI 15850). This is the restriction note from the CosIng inventory. For authoritative conditions and limits, always refer to the linked annex entries.

How do I check if my formula contains PIGMENT RED 57:1?

Use the INCI Checker to screen a full ingredient list across selected markets, or use the substance market comparison to review this identity across all supported market datasets.

InventoryRef 7981913/08/2020

PIGMENT RED 57:1

Calcium 3-hydroxy-4-[(4-methyl-2-sulphonatophenyl)azo]-2-naphthoate (CI 15850)

PIGMENT RED 57:1 is linked to 2 EU annex records on this page. Inventory note: III/296 (Pigment Red 57) IV/27 (CI 15850).

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Regulatory evidence by market

This matrix separates verified ingredient rules from sources that are mapped but not yet imported. No imported rule does not mean the ingredient is permitted.

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Market	Evidence status	Records	Source language
European Union	Evidence linked Restricted entry found Open this evidence	2	English and EU languages
Great Britain	Evidence linked Permitted list with conditions Open this evidence	1	English
Canada	Source mapped Official source mapped; ingredient rule not imported	0	English and French
New Zealand	Evidence linked Permitted list with conditions Open this evidence	1	English
ASEAN	Source mapped Official source mapped; ingredient rule not imported	0	English and national languages
China	Source mapped Official source mapped; ingredient rule not imported	0	Chinese with selected English material
Japan	Source mapped Official source mapped; ingredient rule not imported	0	Japanese; official English translation available
South Korea	Source mapped Official source mapped; ingredient rule not imported	0	Korean with some English names
United States	Source mapped Official source mapped; ingredient rule not imported	0	English
Australia	Source mapped Official source mapped; ingredient rule not imported	0	English
Brazil	Source mapped Official source mapped; ingredient rule not imported	0	Portuguese with INCI crosswalks
India	Source mapped Official source mapped; ingredient rule not imported	0	English and Hindi
Saudi Arabia	Source mapped Official source mapped; ingredient rule not imported	0	Arabic and English

Chemical identity and properties

PubChem 2D chemical structure for CAS 5281-04-9

CAS 5281-04-9PubChem CID 135423095

2-Naphthalenecarboxylic acid, 3-hydroxy-4-((4-methyl-2-sulfophenyl)azo)-, calcium salt (1:1)

IUPAC name: calcium 2-[(3-carboxy-2-oxidonaphthalen-1-yl)diazenyl]-5-methylbenzenesulfonate

Molecular formula: C18H12CaN2O6S
Molecular weight: 424.4 g/mol
Exact mass: 424.0041981 Da
Topological polar surface area: 151.0 Å²
Hydrogen-bond donors: 1
Hydrogen-bond acceptors: 8
Covalent units: 2
Defined stereocentres: 0

Also known as

Calcium 3-hydroxy-4-((4-methyl-2-sulphonatophenyl)azo)-2-naphthoatecalcium 3-hydroxy-4-[(4-methyl-2-sulphonatophenyl)azo]-2-naphthoate2-Naphthalenecarboxylic acid, 3-hydroxy-4-[(4-methyl-2-sulfophenyl)azo]-, calcium salt (1:1)RefChem:476607Lithol Rubin BCAD&C Red No. 7Brilliant Carmine 6BECW0LZ41X8

16 more reported names

Calcium 3-hydroxy-4-((4-methyl-2-sulfonatophenyl)diazenyl)-2-naphthoatered 7C.I. 15850:1Calcium 3-hydroxy-4-(4-methyl-2-sulphonatophenyl)azo-2-naphthoateLithol Rubine BKLithol rubin B ca2-Naphthalenecarboxylic acid, 3-hydroxy-4-(2-(4-methyl-2-sulfophenyl)diazenyl)-, calcium salt (1:1)D & C Red no. 7CCRIS 4903CI 15850:1 (Ca salt)EINECS 226-109-5LITHOLRUBINED&C Red 7UNII-ECW0LZ41X8DC RED NO. 7AKA202

Open full PubChem record PubChem annotations 3D structure image

External database identifiers

ChEMBL:CHEMBL2028348
EPA DTXSID:DTXSID201045895
EPA DTXSID:DTXSID30967273
EPA DTXSID:DTXSID7027594

Retrieved from NIH PubChem on 2026-09-02 by checksum-valid CAS matching. Chemical properties do not replace the regulatory decision on this page.

Inventory details for PIGMENT RED 57:1

INCI name

PIGMENT RED 57:1

Description

Calcium 3-hydroxy-4-[(4-methyl-2-sulphonatophenyl)azo]-2-naphthoate (CI 15850)

Record provenance

Inventory reference: 79819
Imported identity: PIGMENT RED 57:1
Source update: 13/08/2020

European Commission CosIng source notes

Annex records for PIGMENT RED 57:1

Annex III Restriction reference

Entry 296

Pigment Red 57

CAS: 5858-81-1

EC: 227-497-9

Annex IV Restriction reference

Entry 27

CI 15850

EC: 226-109-5

Key data

CAS

29092-56-6; 5281-04-9

226-109-5

Restriction

III/296 (Pigment Red 57) IV/27 (CI 15850)

Function

COLORANT: Exclusively or mainly intended to colour the cosmetic product, the body as a whole or certain parts thereof, by absorption or reflection of visible light. All authorised colorants are substances in the positive list of Annex IV to the Cosmetics Regulation 1223/2009.
HAIR DYEING: Imparting color to hair. Hair dyeing preparations may be temporary, semi-permanent, or permanent, depending on the length of time the colorant remains on the hair.

Official EU ingredient-name evidence

The ingredient name exactly matches the official 2025 EU glossary of common ingredient names.

#21032 · PIGMENT RED 57:1

The 3 markets that hold a rule for this substance do not classify it the same way.

restricted: European Union
permitted on a positive list: Great Britain New Zealand

See every substance the markets disagree about

Ingredients with overlapping formulation functions

PIGMENT RED 172 ALUMINUM LAKECOLORANT, HAIR DYEING

PIGMENT RED 173 ALUMINUM LAKECOLORANT

PIGMENT RED 53COLORANT

PIGMENT RED 57COLORANT

PIGMENT RED 83COLORANT, HAIR DYEING

PIGMENT RED 90:1 ALUMINUM LAKECOLORANT, HAIR DYEING

PIGMENT VIOLET 23COLORANT, HAIR DYEING

PYRITE POWDERBULKING, COLORANT

Additional official and scientific sources

11 external databases to check this identity in

Each link searches that source for this identity. What each source is, and its legal weight

ECHA CHEM / Information on chemicals PubChem PUG REST EU Safety Gate cosmetic product alerts ECHA CHEM US EPA CompTox Cosmetic Ingredient Review safety assessments FDA Global Substance Registration System ILO/WHO International Chemical Safety Cards Japan NITE-CHRIP NIOSH Pocket Guide to Chemical Hazards OECD eChemPortal

How PIGMENT RED 57:1 appears in the CosIng inventory

The CosIng inventory lists PIGMENT RED 57:1 as a cosmetic ingredient and this page links it to 2 annex records. The inventory entry captures names and identifiers, while the annex records show where the substance is prohibited, restricted or positively listed in EU cosmetics law.

PIGMENT RED 57:1 is also tagged with 2 cosmetic functions in the official data. Function labels describe intended use, but they do not replace regulatory review of linked annex records before formulation or labelling work.

Frequently asked questions

PIGMENT RED 57:1 appears in the EU CosIng inventory and has linked annex records. Check the annex records above for applicable restrictions, concentration limits and conditions of use. Annex II listing means prohibited; Annex III means restricted; Annexes IV, V and VI mean permitted under specified conditions.

The restriction field for PIGMENT RED 57:1 reads: "III/296 (Pigment Red 57) IV/27 (CI 15850)". This is the restriction note recorded in the CosIng inventory for this ingredient. For authoritative conditions and limits, always refer to the linked annex entries above.

According to the EU CosIng inventory, PIGMENT RED 57:1 carries the following function designation(s):

CAS 29092-56-6; 5281-04-9 may appear across multiple EU annex records. Viewing the CAS lookup page shows all Annex II–VI entries sharing this identifier, which is useful for identifying cross-annex regulatory status of the same chemical substance.

Use the INCI Checker to screen a full ingredient list across selected markets, or compare this substance across all supported market datasets.

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Source note for PIGMENT RED 57:1

This page combines the CosIng inventory entry for PIGMENT RED 57:1 with 2 linked Annex II–VI records from the local dataset built from public European Commission cosmetic ingredient materials.

Use this inventory page to research PIGMENT RED 57:1 and compare linked records, but verify restrictions and legal status against the current official source text and law before making regulatory decisions.

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