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CAS 221249-87-2 may appear across multiple EU annex records. The CAS lookup page shows all Annex II–VI entries sharing this identifier, useful for identifying cross-annex regulatory status of the same chemical substance.

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InventoryRef 7974315/10/2010

POTASSIUM TRISPHOSPHONOMETHYLAMINE OXIDE

Nitrilotris(methanephosphonic acid) N-oxide, tripotassium salt

POTASSIUM TRISPHOSPHONOMETHYLAMINE OXIDE is listed in the EU CosIng inventory, but no direct annex records are linked on this page yet.

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Regulatory evidence by market

No rule for this ingredient has been imported for any of the 13 markets tracked here.

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Chemical identity and properties

PubChem 2D chemical structure for CAS 221249-87-2

CAS 221249-87-2PubChem CID 71587651

Potassium trisphosphonomethylamine oxide

IUPAC name: tripotassium;[bis[[hydroxy(oxido)phosphoryl]methyl]-oxidoazaniumyl]methyl-hydroxyphosphinate

Molecular formula: C3H9K3NO10P3
Molecular weight: 429.32 g/mol
Exact mass: 428.8350509 Da
Topological polar surface area: 199.0 Å²
Hydrogen-bond donors: 3
Hydrogen-bond acceptors: 10
Covalent units: 4
Defined stereocentres: 0

Also known as

Sequion CLRUNII-FLR8103G8RFLR8103G8RPotassium trisphosphonomethylamine oxide [INCI]Phosphonic acid, ((oxidonitrilo)tris(methylene))tris-, tripotassium saltRefChem:175638Tripotassium [nitroryltris(methylene)]tris[hydrogen (phosphonate)]

Open full PubChem record PubChem annotations 3D structure image

External database identifiers

EPA DTXSID:DTXSID30176646

Retrieved from NIH PubChem on 2026-08-31 by checksum-valid CAS matching. Chemical properties do not replace the regulatory decision on this page.

Inventory details for POTASSIUM TRISPHOSPHONOMETHYLAMINE OXIDE

INCI name

POTASSIUM TRISPHOSPHONOMETHYLAMINE OXIDE

Description

Nitrilotris(methanephosphonic acid) N-oxide, tripotassium salt

Record provenance

Inventory reference: 79743
Imported identity: POTASSIUM TRISPHOSPHONOMETHYLAMINE OXIDE
Source update: 15/10/2010

European Commission CosIng source notes

Annex records for POTASSIUM TRISPHOSPHONOMETHYLAMINE OXIDE

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Key data

CAS

221249-87-2

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Restriction

—

Function

CHELATING: Forming complexes with metal ions which could affect the stability and/or appearance of cosmetics.

Official EU ingredient-name evidence

The ingredient name exactly matches the official 2025 EU glossary of common ingredient names.

#22789 · POTASSIUM TRISPHOSPHONOMETHYLAMINE OXIDE

Ingredients with overlapping formulation functions

POTASSIUM ETHYL ESTER OF PVM/MA COPOLYMERCHELATING

POTASSIUM GLUCONATECHELATING, SKIN PROTECTING

POTASSIUM HYDROGEN CAPRYLHYDROXAMATECHELATING

POTASSIUM POLYPHOSPHATECHELATING

POTASSIUM VANADYL TUNGSTATE ANTIMONATEANTIMICROBIAL, ANTIOXIDANT, CHELATING

PROPANE TRICARBOXYLIC ACIDBUFFERING, CHELATING

PYRICARBATECHELATING, SKIN CONDITIONING

RIBONIC ACIDBUFFERING, CHELATING

Additional official and scientific sources

11 external databases to check this identity in

Each link searches that source for this identity. What each source is, and its legal weight

ECHA CHEM / Information on chemicals PubChem PUG REST EU Safety Gate cosmetic product alerts ECHA CHEM US EPA CompTox Cosmetic Ingredient Review safety assessments FDA Global Substance Registration System ILO/WHO International Chemical Safety Cards Japan NITE-CHRIP NIOSH Pocket Guide to Chemical Hazards OECD eChemPortal

How POTASSIUM TRISPHOSPHONOMETHYLAMINE OXIDE appears in the CosIng inventory

The CosIng inventory lists POTASSIUM TRISPHOSPHONOMETHYLAMINE OXIDE as a cosmetic ingredient and this page links it to 0 annex records. The inventory entry captures names and identifiers, while the annex records show where the substance is prohibited, restricted or positively listed in EU cosmetics law.

POTASSIUM TRISPHOSPHONOMETHYLAMINE OXIDE is also tagged with 1 cosmetic function in the official data. Function labels describe intended use, but they do not replace regulatory review of linked annex records before formulation or labelling work.

Frequently asked questions

POTASSIUM TRISPHOSPHONOMETHYLAMINE OXIDE is listed in the EU CosIng ingredient inventory with no direct annex restriction records linked at this time. Absence of an annex link does not guarantee unrestricted use — always verify against the current official CosIng database before formulating.

According to the EU CosIng inventory, POTASSIUM TRISPHOSPHONOMETHYLAMINE OXIDE carries the following function designation(s):

CHELATING

CAS 221249-87-2 may appear across multiple EU annex records. Viewing the CAS lookup page shows all Annex II–VI entries sharing this identifier, which is useful for identifying cross-annex regulatory status of the same chemical substance.

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Source note for POTASSIUM TRISPHOSPHONOMETHYLAMINE OXIDE

This page reproduces the CosIng inventory entry for POTASSIUM TRISPHOSPHONOMETHYLAMINE OXIDE from public European Commission cosmetic ingredient materials and shows linked identifiers even when no direct annex match is currently attached.

Use this inventory page to research POTASSIUM TRISPHOSPHONOMETHYLAMINE OXIDE and compare linked records, but verify restrictions and legal status against the current official source text and law before making regulatory decisions.

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