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InventoryRef 7879015/10/2010

POLYGLYCERYL-2 TRIISOSTEARATE

1,2,3-Propanetriol, homopolymer, isooctadecanoates (1:3) (2 mol glycerol average molar ratio)

POLYGLYCERYL-2 TRIISOSTEARATE is listed in the EU CosIng inventory, but no direct annex records are linked on this page yet.

Regulatory evidence by market

No rule for this ingredient has been imported for any of the 13 markets tracked here.

That describes this inventory, not the law. No imported rule is not evidence that an ingredient is permitted: a rule may exist under another name or identifier, or in a dataset not yet imported here.

Chemical identity and properties

PubChem 2D chemical structure for CAS 120486-24-0
CAS 120486-24-0PubChem CID 11845292

Polyglyceryl-2 Triisostearate

The CIR Expert Panel concluded that the 274 polyglyceryl fatty acid esters listed below are safe in cosmetics in the present practices of use and concentration described in this safety assessment when formulated to be non-irritating..Polyglyceryl-2 Triisostearate... Cosmetic Ingredient Review (CIR)

IUPAC name
[3-[2,3-bis(16-methylheptadecanoyloxy)propoxy]-2-hydroxypropyl] 16-methylheptadecanoate
Molecular formula
C60H116O8
Molecular weight
965.6 g/mol
Exact mass
964.86702065 Da
XLogP3
23.6
Topological polar surface area
108.0 Ų
Hydrogen-bond donors
1
Hydrogen-bond acceptors
8
Covalent units
1
Defined stereocentres
0

Also known as

Neorex pgisSalacos 43VCithrol PG23ISRisorex PGIS23Cosmol 43SVCosmol 43VUNII-68DUY2D39A68DUY2D39A
3 more reported names
Diglyceryl triisostearateRefChem:175155OWRMXHRUFYLLQP-UHFFFAOYSA-N

Evidence from additional scientific databases

NIH PubChem PUG-View
Exact identifier match11845292

Attributed physical-property, hazard, environmental and use annotations.

  • Note: This chemical does not meet GHS hazard criteria for 100% (37 of 37) of all reports. Source: European Chemicals Agency (ECHA)
  • GHS Hazard Statements: Not Classified; Reported as not meeting GHS hazard criteria by 37 of 37 companies. For more detailed information, please visit ECHA C&L website. Source: European Chemicals Agency (ECHA)
  • ECHA C&L Notifications Summary: Aggregated GHS information provided per 37 reports by companies from 2 notifications to the ECHA C&L Inventory.; Reported as not meeting GHS hazard criteria per 37 of 37 reports by companies.; There are 0 notifications provided by 0 of 37 reports by companies with hazard statement code(s).; Information may vary between notifications depending on impurities, additives, and other factors. The percentage value in parenthesis indicates the notified classification ratio from companies that provide hazard codes. Only hazard codes with percentage values above 10% are shown. For more detailed information, please visit ECHA C&L website. Source: European Chemicals Agency (ECHA)
  • Note: This chemical does not meet GHS hazard criteria for 100% (8 of 8) of all reports. Source: European Chemicals Agency (ECHA)
  • GHS Hazard Statements: Not Classified; Reported as not meeting GHS hazard criteria by 8 of 8 companies. For more detailed information, please visit ECHA C&L website. Source: European Chemicals Agency (ECHA)
  • ECHA C&L Notifications Summary: Aggregated GHS information provided per 8 reports by companies from 1 notifications to the ECHA C&L Inventory.; Reported as not meeting GHS hazard criteria per 8 of 8 reports by companies.; There are 0 notifications provided by 0 of 8 reports by companies with hazard statement code(s).; Information may vary between notifications depending on impurities, additives, and other factors. The percentage value in parenthesis indicates the notified classification ratio from companies that provide hazard codes. Only hazard codes with percentage values above 10% are shown. For more detailed information, please visit ECHA C&L website. Source: European Chemicals Agency (ECHA)
  • Cosmetic Ingredient Review Conclusion: The CIR Expert Panel concluded that the 274 polyglyceryl fatty acid esters listed below are safe in cosmetics in the present practices of use and concentration described in this safety assessment when formulated to be non-irritating..Polyglyceryl-2 Triisostearate... Source: Cosmetic Ingredient Review (CIR)
  • Cosmetic Ingredient Review Finding(s): Safe for use in cosmetics, with qualifications Source: Cosmetic Ingredient Review (CIR)

Mapped by: Existing checksum-valid CAS to unique PubChem CID match. Retrieved: 2026-08-31. Open source record

Scientific classifications and hazard annotations provide context and do not replace the market-specific regulatory decision shown above.

Additional source coverage and match status
SourceResultChecked
NIH PubChem PUG-ViewExact match2026-08-31

A recorded no-match is useful evidence that the source was checked; it is not a claim that the substance does not exist elsewhere.

Retrieved from NIH PubChem on 2026-08-31 by checksum-valid CAS matching. Chemical properties do not replace the regulatory decision on this page.

Inventory details for POLYGLYCERYL-2 TRIISOSTEARATE

INCI name

POLYGLYCERYL-2 TRIISOSTEARATE

Description

1,2,3-Propanetriol, homopolymer, isooctadecanoates (1:3) (2 mol glycerol average molar ratio)

Record provenance

Inventory reference
78790
Imported identity
POLYGLYCERYL-2 TRIISOSTEARATE
Source update
15/10/2010
European Commission CosIng source notes

Key data

EC
Restriction
Function
SURFACTANT - EMULSIFYING
Helping suspensions or dispersions of liquids in a second liquid by reducing the surface tension of the substances to be emulsified.

Official EU ingredient-name evidence

The ingredient name exactly matches the official 2025 EU glossary of common ingredient names.

Ingredients with overlapping formulation functions

Additional official and scientific sources

11 external databases to check this identity in

How POLYGLYCERYL-2 TRIISOSTEARATE appears in the CosIng inventory

The CosIng inventory lists POLYGLYCERYL-2 TRIISOSTEARATE as a cosmetic ingredient and this page links it to 0 annex records. The inventory entry captures names and identifiers, while the annex records show where the substance is prohibited, restricted or positively listed in EU cosmetics law.

POLYGLYCERYL-2 TRIISOSTEARATE is also tagged with 1 cosmetic function in the official data. Function labels describe intended use, but they do not replace regulatory review of linked annex records before formulation or labelling work.

Frequently asked questions

POLYGLYCERYL-2 TRIISOSTEARATE is listed in the EU CosIng ingredient inventory with no direct annex restriction records linked at this time. Absence of an annex link does not guarantee unrestricted use — always verify against the current official CosIng database before formulating.

According to the EU CosIng inventory, POLYGLYCERYL-2 TRIISOSTEARATE carries the following function designation(s):

CAS 120486-24-0 may appear across multiple EU annex records. Viewing the CAS lookup page shows all Annex II–VI entries sharing this identifier, which is useful for identifying cross-annex regulatory status of the same chemical substance.

Use the INCI Checker to screen a full ingredient list across selected markets, or compare this substance across all supported market datasets.

Source note for POLYGLYCERYL-2 TRIISOSTEARATE

This page reproduces the CosIng inventory entry for POLYGLYCERYL-2 TRIISOSTEARATE from public European Commission cosmetic ingredient materials and shows linked identifiers even when no direct annex match is currently attached.

Use this inventory page to research POLYGLYCERYL-2 TRIISOSTEARATE and compare linked records, but verify restrictions and legal status against the current official source text and law before making regulatory decisions.

Tools & next steps

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