How do I check if my formula contains POLYGLYCERYL-2 ISOSTEARATE?

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InventoryRef 7878115/10/2010

POLYGLYCERYL-2 ISOSTEARATE

Ester of diglycerol and isostearic acid

POLYGLYCERYL-2 ISOSTEARATE is listed in the EU CosIng inventory, but no direct annex records are linked on this page yet.

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Regulatory evidence by market

No rule for this ingredient has been imported for any of the 13 markets tracked here.

That describes this inventory, not the law. No imported rule is not evidence that an ingredient is permitted: a rule may exist under another name or identifier, or in a dataset not yet imported here.

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Chemical identity and properties

PubChem 2D chemical structure for CAS 73296-86-3

CAS 73296-86-3PubChem CID 3037295

Diglyceryl isostearate

IUPAC name: 3-(2,3-dihydroxypropoxy)propane-1,2-diol;16-methylheptadecanoic acid

Molecular formula: C24H50O7
Molecular weight: 450.6 g/mol
Exact mass: 450.35565393 Da
Topological polar surface area: 127.0 Å²
Hydrogen-bond donors: 5
Hydrogen-bond acceptors: 7
Covalent units: 2
Defined stereocentres: 0

Also known as

Diglycerol isostearateEINECS 277-361-8Isooctadecanoic acid, ester with oxybis[propanediol]Isooctadecanoic acid, ester with oxybis(propanediol)RefChem:587616277-361-8606-238-7606-256-5

2 more reported names

CKIYSWRVDRLJDR-UHFFFAOYSA-N16-Methylheptadecanoic acid--3,3'-oxydi(propane-1,2-diol) (1/1)

Open full PubChem record PubChem annotations 3D structure image

External database identifiers

EPA DTXSID:DTXSID70940722

Retrieved from NIH PubChem on 2026-08-31 by checksum-valid CAS matching. Chemical properties do not replace the regulatory decision on this page.

PubChem 2D chemical structure for CAS 81752-33-2

CAS 81752-33-2PubChem CID 9910684

Polyglyceryl-2 Isostearate

The CIR Expert Panel concluded that the 274 polyglyceryl fatty acid esters listed below are safe in cosmetics in the present practices of use and concentration described in this safety assessment when formulated to be non-irritating..Polyglyceryl-2 Isostearate... — Cosmetic Ingredient Review (CIR)

IUPAC name: [3-(2,3-dihydroxypropoxy)-2-hydroxypropyl] 16-methylheptadecanoate

Molecular formula: C24H48O6
Molecular weight: 432.6 g/mol
Exact mass: 432.34508925 Da
XLogP3: 6.4
Topological polar surface area: 96.2 Å²
Hydrogen-bond donors: 3
Hydrogen-bond acceptors: 6
Covalent units: 1
Defined stereocentres: 0

Also known as

Diglycerin monoisostearate7B8OE71MQCIsooctadecanoic acid, monoester with oxybis(propanediol)Isooctadecanoic acid, monoester with oxybis[propanediol]RefChem:866532685-535-3UNII-7B8OE71MQCWVRJNKBXUMGBGG-UHFFFAOYSA-N

1 more reported name

3-(2,3-DIHYDROXYPROPOXY)-2-HYDROXYPROPYL 16-METHYLHEPTADECANOATE

Open full PubChem record PubChem annotations 3D structure image

External database identifiers

EPA DTXSID:DTXSID80994014

Retrieved from NIH PubChem on 2026-08-31 by checksum-valid CAS matching. Chemical properties do not replace the regulatory decision on this page.

Inventory details for POLYGLYCERYL-2 ISOSTEARATE

INCI name

POLYGLYCERYL-2 ISOSTEARATE

Description

Ester of diglycerol and isostearic acid

Record provenance

Inventory reference: 78781
Imported identity: POLYGLYCERYL-2 ISOSTEARATE
Source update: 15/10/2010

European Commission CosIng source notes

Annex records for POLYGLYCERYL-2 ISOSTEARATE

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Key data

CAS

73296-86-3 / 81752-33-2

277-361-8

Restriction

—

Function

SURFACTANT - EMULSIFYING: Helping suspensions or dispersions of liquids in a second liquid by reducing the surface tension of the substances to be emulsified.

Official EU ingredient-name evidence

The ingredient name exactly matches the official 2025 EU glossary of common ingredient names.

#21812 · POLYGLYCERYL-2 ISOSTEARATE

Ingredients with overlapping formulation functions

POLYGLYCERYL-2 HYDROXYPROPYL ETHYLHEXYL ETHERCLEANSING, SURFACTANT - CLEANSING, SURFACTANT - EMULSIFYING

POLYGLYCERYL-2 HYDROXYPROPYL LAURYL ETHERCLEANSING, SURFACTANT - CLEANSING, SURFACTANT - EMULSIFYING

POLYGLYCERYL-2 ISOPALMITATESURFACTANT - EMULSIFYING

POLYGLYCERYL-2 ISOPALMITATE/SEBACATESURFACTANT - EMULSIFYING

POLYGLYCERYL-2 LANOLIN ALCOHOL ETHERSURFACTANT - EMULSIFYING

POLYGLYCERYL-2 LAURATESURFACTANT - EMULSIFYING

POLYGLYCERYL-2 LAURYL ETHERCLEANSING, SURFACTANT - CLEANSING, SURFACTANT - EMULSIFYING, SURFACTANT - FOAM BOOSTING

POLYGLYCERYL-2 MYRISTATESURFACTANT - EMULSIFYING

Additional official and scientific sources

11 external databases to check this identity in

Each link searches that source for this identity. What each source is, and its legal weight

ECHA CHEM / Information on chemicals PubChem PUG REST EU Safety Gate cosmetic product alerts ECHA CHEM US EPA CompTox Cosmetic Ingredient Review safety assessments FDA Global Substance Registration System ILO/WHO International Chemical Safety Cards Japan NITE-CHRIP NIOSH Pocket Guide to Chemical Hazards OECD eChemPortal

How POLYGLYCERYL-2 ISOSTEARATE appears in the CosIng inventory

The CosIng inventory lists POLYGLYCERYL-2 ISOSTEARATE as a cosmetic ingredient and this page links it to 0 annex records. The inventory entry captures names and identifiers, while the annex records show where the substance is prohibited, restricted or positively listed in EU cosmetics law.

POLYGLYCERYL-2 ISOSTEARATE is also tagged with 1 cosmetic function in the official data. Function labels describe intended use, but they do not replace regulatory review of linked annex records before formulation or labelling work.

Frequently asked questions

POLYGLYCERYL-2 ISOSTEARATE is listed in the EU CosIng ingredient inventory with no direct annex restriction records linked at this time. Absence of an annex link does not guarantee unrestricted use — always verify against the current official CosIng database before formulating.

According to the EU CosIng inventory, POLYGLYCERYL-2 ISOSTEARATE carries the following function designation(s):

SURFACTANT - EMULSIFYING

CAS 73296-86-3 / 81752-33-2 may appear across multiple EU annex records. Viewing the CAS lookup page shows all Annex II–VI entries sharing this identifier, which is useful for identifying cross-annex regulatory status of the same chemical substance.

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Source note for POLYGLYCERYL-2 ISOSTEARATE

This page reproduces the CosIng inventory entry for POLYGLYCERYL-2 ISOSTEARATE from public European Commission cosmetic ingredient materials and shows linked identifiers even when no direct annex match is currently attached.

Use this inventory page to research POLYGLYCERYL-2 ISOSTEARATE and compare linked records, but verify restrictions and legal status against the current official source text and law before making regulatory decisions.

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