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CAS 67938-21-0 may appear across multiple EU annex records. The CAS lookup page shows all Annex II–VI entries sharing this identifier, useful for identifying cross-annex regulatory status of the same chemical substance.

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InventoryRef 7877715/10/2010

POLYGLYCERYL-2 DIISOSTEARATE

Diester of diglycerol and isostearic acid

POLYGLYCERYL-2 DIISOSTEARATE is listed in the EU CosIng inventory, but no direct annex records are linked on this page yet.

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Regulatory evidence by market

No rule for this ingredient has been imported for any of the 13 markets tracked here.

That describes this inventory, not the law. No imported rule is not evidence that an ingredient is permitted: a rule may exist under another name or identifier, or in a dataset not yet imported here.

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Chemical identity and properties

PubChem 2D chemical structure for CAS 67938-21-0

CAS 67938-21-0PubChem CID 10122822

Polyglyceryl-2 Diisostearate

The CIR Expert Panel concluded that the 274 polyglyceryl fatty acid esters listed below are safe in cosmetics in the present practices of use and concentration described in this safety assessment when formulated to be non-irritating..Polyglyceryl-2 Diisostearate... — Cosmetic Ingredient Review (CIR)

IUPAC name: [2-hydroxy-3-[2-hydroxy-3-(16-methylheptadecanoyloxy)propoxy]propyl] 16-methylheptadecanoate

Molecular formula: C42H82O7
Molecular weight: 699.1 g/mol
Exact mass: 698.60605495 Da
XLogP3: 14.9
Topological polar surface area: 102.0 Å²
Hydrogen-bond donors: 2
Hydrogen-bond acceptors: 7
Covalent units: 1
Defined stereocentres: 0

Also known as

Diglyceryl diisostearateDG195GP57PDERMOL DGDISMATSUNATE DIRISOREX PGIS22CITHROL PG 22ISEINECS 267-821-6SALACOS 42V

16 more reported names

COSMOL 42VMATSUNATE MI-220SUNSOFT Q-192BDIGLYCERIN DIISOSTEARATES-FACE IS-202 PIsooctadecanoic acid, diester with diglycerolEC 267-821-6Isooctadecanoic acid, diester with oxybis(propenediol)Di(isooctadecanoic) acid, diester with oxydi(propanediol)ISOOCTADECANOIC ACID, DIESTER WITH OXYBIS(PROPANEDIOL)Isooctadecanoic acid, diester with oxybis[propanediol]RefChem:866530Isooctadecanoic acid, diester with oxybispropanediolUNII-DG195GP57PHOSTACERIN DGIPolyglyceryl-2 sesquiisostearate

Open full PubChem record PubChem annotations 3D structure image

External database identifiers

EPA DTXSID:DTXSID301021513

Retrieved from NIH PubChem on 2026-08-31 by checksum-valid CAS matching. Chemical properties do not replace the regulatory decision on this page.

Inventory details for POLYGLYCERYL-2 DIISOSTEARATE

INCI name

POLYGLYCERYL-2 DIISOSTEARATE

Description

Diester of diglycerol and isostearic acid

Record provenance

Inventory reference: 78777
Imported identity: POLYGLYCERYL-2 DIISOSTEARATE
Source update: 15/10/2010

European Commission CosIng source notes

Annex records for POLYGLYCERYL-2 DIISOSTEARATE

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Key data

CAS

67938-21-0

267-821-6

Restriction

—

Function

SURFACTANT - EMULSIFYING: Helping suspensions or dispersions of liquids in a second liquid by reducing the surface tension of the substances to be emulsified.

Official EU ingredient-name evidence

The ingredient name exactly matches the official 2025 EU glossary of common ingredient names.

#21802 · POLYGLYCERYL-2 DIISOSTEARATE

Records sharing a CAS or EC identity

POLYGLYCERYL-2 SESQUIISOSTEARATE

Ingredients with overlapping formulation functions

POLYGLYCERYL-10 TRIDECANOATESKIN CONDITIONING - EMOLLIENT, SURFACTANT - EMULSIFYING

POLYGLYCERYL-12 BIS(HYDROXYPROPYL ETHYLHEXYL ETHER)CLEANSING, SURFACTANT - CLEANSING, SURFACTANT - EMULSIFYING

POLYGLYCERYL-2 CAPRATESURFACTANT - EMULSIFYING

POLYGLYCERYL-2 CAPRYLATESURFACTANT - EMULSIFYING

POLYGLYCERYL-2 DISTEARATESURFACTANT - EMULSIFYING

POLYGLYCERYL-2 HYDROXYPROPYL ETHYLHEXYL ETHERCLEANSING, SURFACTANT - CLEANSING, SURFACTANT - EMULSIFYING

POLYGLYCERYL-2 HYDROXYPROPYL LAURYL ETHERCLEANSING, SURFACTANT - CLEANSING, SURFACTANT - EMULSIFYING

POLYGLYCERYL-2 ISOPALMITATESURFACTANT - EMULSIFYING

Additional official and scientific sources

11 external databases to check this identity in

Each link searches that source for this identity. What each source is, and its legal weight

ECHA CHEM / Information on chemicals PubChem PUG REST EU Safety Gate cosmetic product alerts ECHA CHEM US EPA CompTox Cosmetic Ingredient Review safety assessments FDA Global Substance Registration System ILO/WHO International Chemical Safety Cards Japan NITE-CHRIP NIOSH Pocket Guide to Chemical Hazards OECD eChemPortal

How POLYGLYCERYL-2 DIISOSTEARATE appears in the CosIng inventory

The CosIng inventory lists POLYGLYCERYL-2 DIISOSTEARATE as a cosmetic ingredient and this page links it to 0 annex records. The inventory entry captures names and identifiers, while the annex records show where the substance is prohibited, restricted or positively listed in EU cosmetics law.

POLYGLYCERYL-2 DIISOSTEARATE is also tagged with 1 cosmetic function in the official data. Function labels describe intended use, but they do not replace regulatory review of linked annex records before formulation or labelling work.

Frequently asked questions

POLYGLYCERYL-2 DIISOSTEARATE is listed in the EU CosIng ingredient inventory with no direct annex restriction records linked at this time. Absence of an annex link does not guarantee unrestricted use — always verify against the current official CosIng database before formulating.

According to the EU CosIng inventory, POLYGLYCERYL-2 DIISOSTEARATE carries the following function designation(s):

SURFACTANT - EMULSIFYING

CAS 67938-21-0 may appear across multiple EU annex records. Viewing the CAS lookup page shows all Annex II–VI entries sharing this identifier, which is useful for identifying cross-annex regulatory status of the same chemical substance.

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Source note for POLYGLYCERYL-2 DIISOSTEARATE

This page reproduces the CosIng inventory entry for POLYGLYCERYL-2 DIISOSTEARATE from public European Commission cosmetic ingredient materials and shows linked identifiers even when no direct annex match is currently attached.

Use this inventory page to research POLYGLYCERYL-2 DIISOSTEARATE and compare linked records, but verify restrictions and legal status against the current official source text and law before making regulatory decisions.

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