Is SPHINGOLIPIDS safe to use in EU cosmetics?

SPHINGOLIPIDS is listed in the EU CosIng ingredient inventory with no direct annex restriction records linked at this time. Always verify against the current official CosIng database before formulating.

What function does SPHINGOLIPIDS serve in cosmetics?

According to the EU CosIng inventory, SPHINGOLIPIDS carries the following function designation(s): SKIN CONDITIONING, SKIN CONDITIONING - EMOLLIENT, SKIN PROTECTING.

What other records share CAS 85116-74-1?

CAS 85116-74-1 may appear across multiple EU annex records. The CAS lookup page shows all Annex II–VI entries sharing this identifier, useful for identifying cross-annex regulatory status of the same chemical substance.

How do I check if my formula contains SPHINGOLIPIDS?

Use the INCI Checker to screen a full ingredient list across selected markets, or use the substance market comparison to review this identity across all supported market datasets.

InventoryRef 7875315/10/2010

SPHINGOLIPIDS

Sphingolipids

SPHINGOLIPIDS is listed in the EU CosIng inventory, but no direct annex records are linked on this page yet.

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Regulatory evidence by market

No rule for this ingredient has been imported for any of the 13 markets tracked here.

That describes this inventory, not the law. No imported rule is not evidence that an ingredient is permitted: a rule may exist under another name or identifier, or in a dataset not yet imported here.

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Chemical identity and properties

PubChem 2D chemical structure for CAS 85116-74-1

CAS 85116-74-1PubChem CID 10056286

Cerebrosides

IUPAC name: 2-hydroxy-N-[(E,2S,3R)-3-hydroxy-1-[(2R,3R,4S,5R,6R)-3,4,5-trihydroxy-6-(hydroxymethyl)oxan-2-yl]oxyoctadec-4-en-2-yl]tetracosanamide

Molecular formula: C48H93NO9
Molecular weight: 828.3 g/mol
Exact mass: 827.68503354 Da
XLogP3: 14.9
Topological polar surface area: 169.0 Å²
Hydrogen-bond donors: 7
Hydrogen-bond acceptors: 9
Covalent units: 1
Defined stereocentres: 7

Also known as

RefChem:388873EINECS 285-526-0285-526-0Cerebrosides, bovineGalactosylceramide (bovine spinal cord)GalactosylcerebrosideCerebroside BAC-4Ceramide ?-D-galactosides

6 more reported names

C48H93NO9ZXWQZGROTQMXME-WXUJBLQXSA-N1-O-beta-D-Galactopyranosyl-N-(2-hydroxytetracosanoyl)sphingosine?-Galactosylceramide, from bovine brainCerebrosides - Mixture of hydroxy and non-hydroxy fatty acid2-hydroxy-N-[(E,1S,2R)-2-hydroxy-1-[[(2R,3R,4S,5R,6R)-3,4,5-trihydroxy-6-(hydroxymethyl)tetrahydropyran-2-yl]oxymethyl]heptadec-3-enyl]tetracosanamide

Open full PubChem record PubChem annotations 3D structure image

External database identifiers

ChEMBL:CHEMBL1813975

Retrieved from NIH PubChem on 2026-09-02 by checksum-valid CAS matching. Chemical properties do not replace the regulatory decision on this page.

Inventory details for SPHINGOLIPIDS

INCI name

SPHINGOLIPIDS

Description

Sphingolipids

Record provenance

Inventory reference: 78753
Imported identity: SPHINGOLIPIDS
Source update: 15/10/2010

European Commission CosIng source notes

Annex records for SPHINGOLIPIDS

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Key data

CAS

85116-74-1

285-526-0

Restriction

—

Function

SKIN CONDITIONING: Maintaining the skin in good condition.
SKIN CONDITIONING - EMOLLIENT: Acting as lubricants on the skin surface providing the skin with a soft and smooth appearance.
SKIN PROTECTING: Helping to avoid harmful effects to the skin from external factors.

Official EU ingredient-name evidence

The ingredient name exactly matches the official 2025 EU glossary of common ingredient names.

#27409 · SPHINGOLIPIDS

Records sharing a CAS or EC identity

CEREBROSIDES PHYTOSTERYL GLUCOSIDE/GLUCOSYLCERAMIDE

Ingredients with overlapping formulation functions

SPATHOLOBUS SUBERECTUS EXTRACTANTIMICROBIAL, HAIR CONDITIONING, HUMECTANT, SKIN PROTECTING

SPENT GRAIN EXTRACTANTIOXIDANT; HAIR CONDITIONING; SKIN PROTECTING; SKIN CONDITIONING - HUMECTANT

SPENT GRAIN POWDERANTIOXIDANT; BULKING; HAIR CONDITIONING; SKIN PROTECTING

SPERANSKIA TUBERCULATA EXTRACTANTIOXIDANT, SKIN PROTECTING

SPHINGOMONAS EXTRACTSKIN PROTECTING; SKIN CONDITIONING - MISCELLANEOUS

SPHINGOMONAS FERMENT EXTRACT FILTRATESKIN PROTECTING

SPIRAEA SALICIFOLIA EXTRACTHAIR CONDITIONING; HUMECTANT; SKIN PROTECTING; SKIN CONDITIONING - HUMECTANT

SPIRULINA PLATENSIS EXTRACTSKIN PROTECTING

Additional official and scientific sources

11 external databases to check this identity in

Each link searches that source for this identity. What each source is, and its legal weight

ECHA CHEM / Information on chemicals PubChem PUG REST EU Safety Gate cosmetic product alerts ECHA CHEM US EPA CompTox Cosmetic Ingredient Review safety assessments FDA Global Substance Registration System ILO/WHO International Chemical Safety Cards Japan NITE-CHRIP NIOSH Pocket Guide to Chemical Hazards OECD eChemPortal

How SPHINGOLIPIDS appears in the CosIng inventory

The CosIng inventory lists SPHINGOLIPIDS as a cosmetic ingredient and this page links it to 0 annex records. The inventory entry captures names and identifiers, while the annex records show where the substance is prohibited, restricted or positively listed in EU cosmetics law.

SPHINGOLIPIDS is also tagged with 3 cosmetic functions in the official data. Function labels describe intended use, but they do not replace regulatory review of linked annex records before formulation or labelling work.

Frequently asked questions

SPHINGOLIPIDS is listed in the EU CosIng ingredient inventory with no direct annex restriction records linked at this time. Absence of an annex link does not guarantee unrestricted use — always verify against the current official CosIng database before formulating.

According to the EU CosIng inventory, SPHINGOLIPIDS carries the following function designation(s):

CAS 85116-74-1 may appear across multiple EU annex records. Viewing the CAS lookup page shows all Annex II–VI entries sharing this identifier, which is useful for identifying cross-annex regulatory status of the same chemical substance.

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Use the INCI Checker to screen a full ingredient list across selected markets, or compare this substance across all supported market datasets.

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Source note for SPHINGOLIPIDS

This page reproduces the CosIng inventory entry for SPHINGOLIPIDS from public European Commission cosmetic ingredient materials and shows linked identifiers even when no direct annex match is currently attached.

Use this inventory page to research SPHINGOLIPIDS and compare linked records, but verify restrictions and legal status against the current official source text and law before making regulatory decisions.

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Tools & next steps

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