Is NOPYL ACETATE safe to use in EU cosmetics?

NOPYL ACETATE is listed in the EU CosIng ingredient inventory with no direct annex restriction records linked at this time. Always verify against the current official CosIng database before formulating.

What other records share CAS 128-51-8?

CAS 128-51-8 may appear across multiple EU annex records. The CAS lookup page shows all Annex II–VI entries sharing this identifier, useful for identifying cross-annex regulatory status of the same chemical substance.

How do I check if my formula contains NOPYL ACETATE?

Use the INCI Checker to screen a full ingredient list across selected markets, or use the substance market comparison to review this identity across all supported market datasets.

InventoryRef 7752215/10/2010

NOPYL ACETATE

Bicyclo[3.1.1]hept-2-ene-2-ethanol, 6,6-dimethyl-, acetate

NOPYL ACETATE is listed in the EU CosIng inventory, but no direct annex records are linked on this page yet.

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Regulatory evidence by market

No rule for this ingredient has been imported for any of the 13 markets tracked here.

That describes this inventory, not the law. No imported rule is not evidence that an ingredient is permitted: a rule may exist under another name or identifier, or in a dataset not yet imported here.

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Chemical identity and properties

PubChem 2D chemical structure for CAS 128-51-8

CAS 128-51-8PubChem CID 929336

Nopyl acetate

IUPAC name: 2-[(1R,5S)-6,6-dimethyl-2-bicyclo[3.1.1]hept-2-enyl]ethyl acetate

Molecular formula: C13H20O2
Molecular weight: 208.30 g/mol
Exact mass: 208.146329876 Da
XLogP3: 2.6
Topological polar surface area: 26.3 Å²
Hydrogen-bond donors: 0
Hydrogen-bond acceptors: 2
Covalent units: 1
Defined stereocentres: 2

Also known as

(-)-Nopyl acetateNopyl acetate, (-)-CitroviolNopol acetateF361JE87STOTX3UCY28V2-Norpinene-2-ethanol, 6,6-dimethyl-, acetateEC 800-940-9

16 more reported names

Bicyclo(3.1.1)hept-2-ene-2-ethanol, 6,6-dimethyl-, 2-acetate, (1R,5S)-(1R,5S)-2-(6,6-Dimethylbicyclo(3.1.1)hept-2-en-2-yl) ethyl acetateNSC 1286NSC-1286EINECS 204-891-9NSC-404963AI3-143806,6-Dimethyl-2-norpinene-2-ethanol, acetate2-Pinene-10-methyl acetate7,7-DIMETHYLBICYCLO(3.1.1)HEPT-2-ENE-2-ETHANOL ACETATE2-(6,6-DIMETHYLBICYCLO(3.1.1)HEPT-2-EN-2-YL)ETHYL ACETATBICYCLO(3.1.1)HEPT-2-ENE-2-ETHANOL, 6,6-DIMETHYL-, ACETATE, (1R)-BICYCLO(3.1.1)HEPT-2-ENE-2-ETHANOL, 6,6-DIMETHYL-, ACETATE, (1R,5S)-Bicyclo(3.1.1)hept-2-ene-2-ethanol, 6,6-dimethyl-, 2-acetate6,6-Dimethylbicyclo(3.1.1)-2-heptene-2-ethyl acetateBicyclo[3.1.1]hept-2-ene-2-ethanol, 6,6-dimethyl-, 2-acetate

Open full PubChem record PubChem annotations 3D structure image

External database identifiers

EPA DTXSID:DTXSID40189368

Evidence from additional scientific databases

NIH PubChem PUG-View

Exact identifier match929336

Attributed physical-property, hazard, environmental and use annotations.

Physical Description: CBI; Liquid Source: EPA Chemical Data Reporting (CDR)

Signal: Warning Source: European Chemicals Agency (ECHA)
GHS Hazard Statements: H317 (81.4%): May cause an allergic skin reaction [Warning Sensitization, Skin]; H319 (81.4%): Causes serious eye irritation [Warning Serious eye damage/eye irritation]; H411 (81.4%): Toxic to aquatic life with long lasting effects [Hazardous to the aquatic environment, long-term hazard]; H412 (18.6%): Harmful to aquatic life with long lasting effects [Hazardous to the aquatic environment, long-term hazard] Source: European Chemicals Agency (ECHA)
Precautionary Statement Codes: P261, P264+P265, P272, P273, P280, P302+P352, P305+P351+P338, P321, P333+P317, P337+P317, P362+P364, P391, and P501 (click each P-code to see the statement) Source: European Chemicals Agency (ECHA)
ECHA C&L Notifications Summary: Aggregated GHS information provided per 1716 reports by companies from 6 notifications to the ECHA C&L Inventory. Each notification may be associated with multiple companies.; Information may vary between notifications depending on impurities, additives, and other factors. The percentage value in parenthesis indicates the notified classification ratio from companies that provide hazard codes. Only hazard codes with percentage values above 10% are shown. For more detailed information, please visit ECHA C&L website. Source: European Chemicals Agency (ECHA)
GHS Hazard Statements: H317 (100%): May cause an allergic skin reaction [Warning Sensitization, Skin]; H319 (100%): Causes serious eye irritation [Warning Serious eye damage/eye irritation]; H411 (100%): Toxic to aquatic life with long lasting effects [Hazardous to the aquatic environment, long-term hazard] Source: European Chemicals Agency (ECHA)
ECHA C&L Notifications Summary: Aggregated GHS information provided per 7 reports by companies from 2 notifications to the ECHA C&L Inventory. Each notification may be associated with multiple companies.; Information may vary between notifications depending on impurities, additives, and other factors. The percentage value in parenthesis indicates the notified classification ratio from companies that provide hazard codes. Only hazard codes with percentage values above 10% are shown. For more detailed information, please visit ECHA C&L website. Source: European Chemicals Agency (ECHA)

Consumer Uses: Fragrance Source: EPA Chemical Data Reporting (CDR)

Industry Uses: Fragrance Source: EPA Chemical Data Reporting (CDR)

Mapped by: Existing checksum-valid CAS to unique PubChem CID match. Retrieved: 2026-08-31. Open source record

Scientific classifications and hazard annotations provide context and do not replace the market-specific regulatory decision shown above.

Additional source coverage and match status

Source	Result	Checked
NIH PubChem PUG-View	Exact match	2026-08-31

A recorded no-match is useful evidence that the source was checked; it is not a claim that the substance does not exist elsewhere.

Retrieved from NIH PubChem on 2026-08-31 by checksum-valid CAS matching. Chemical properties do not replace the regulatory decision on this page.

Inventory details for NOPYL ACETATE

INCI name

NOPYL ACETATE

Description

Bicyclo[3.1.1]hept-2-ene-2-ethanol, 6,6-dimethyl-, acetate

Record provenance

Inventory reference: 77522
Imported identity: NOPYL ACETATE
Source update: 15/10/2010

European Commission CosIng source notes

Annex records for NOPYL ACETATE

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Key data

CAS

128-51-8

204-891-9

Restriction

—

Function

FRAGRANCE: Imparting an odour or taste. Creating a perceivable pleasant smell and/or masking a bad smell.

Official EU ingredient-name evidence

The ingredient name exactly matches the official 2025 EU glossary of common ingredient names.

#17609 · NOPYL ACETATE

Ingredients with overlapping formulation functions

NASTURTIUM OFFICINALE LEAF EXTRACTFRAGRANCE, PERFUMING, SKIN CONDITIONING

NEOHESPERIDIN DIHYDROCHALCONEFLAVOURING, FRAGRANCE, PERFUMING

NEOTAMEFRAGRANCE

NEPETA CATARIA OILFRAGRANCE, PERFUMING

NYMPHAEA ALBA LEAF CELL EXTRACTFLAVOURING, FRAGRANCE, PERFUMING, SKIN PROTECTING

NYMPHAEA GIGANTEA FLOWER EXTRACTANTIOXIDANT, FRAGRANCE, HAIR CONDITIONING, PERFUMING, SKIN PROTECTING

OCIMUM AMERICANUM LEAF OILFRAGRANCE, PERFUMING

OCIMUM AMERICANUM LEAF/STEM OILFRAGRANCE, PERFUMING

Additional official and scientific sources

11 external databases to check this identity in

Each link searches that source for this identity. What each source is, and its legal weight

ECHA CHEM / Information on chemicals PubChem PUG REST EU Safety Gate cosmetic product alerts ECHA CHEM US EPA CompTox Cosmetic Ingredient Review safety assessments FDA Global Substance Registration System ILO/WHO International Chemical Safety Cards Japan NITE-CHRIP NIOSH Pocket Guide to Chemical Hazards OECD eChemPortal

How NOPYL ACETATE appears in the CosIng inventory

The CosIng inventory lists NOPYL ACETATE as a cosmetic ingredient and this page links it to 0 annex records. The inventory entry captures names and identifiers, while the annex records show where the substance is prohibited, restricted or positively listed in EU cosmetics law.

NOPYL ACETATE is also tagged with 1 cosmetic function in the official data. Function labels describe intended use, but they do not replace regulatory review of linked annex records before formulation or labelling work.

Frequently asked questions

NOPYL ACETATE is listed in the EU CosIng ingredient inventory with no direct annex restriction records linked at this time. Absence of an annex link does not guarantee unrestricted use — always verify against the current official CosIng database before formulating.

According to the EU CosIng inventory, NOPYL ACETATE carries the following function designation(s):

FRAGRANCE

CAS 128-51-8 may appear across multiple EU annex records. Viewing the CAS lookup page shows all Annex II–VI entries sharing this identifier, which is useful for identifying cross-annex regulatory status of the same chemical substance.

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Source note for NOPYL ACETATE

This page reproduces the CosIng inventory entry for NOPYL ACETATE from public European Commission cosmetic ingredient materials and shows linked identifiers even when no direct annex match is currently attached.

Use this inventory page to research NOPYL ACETATE and compare linked records, but verify restrictions and legal status against the current official source text and law before making regulatory decisions.

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Tools & next steps

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