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CAS 28510-23-8 may appear across multiple EU annex records. The CAS lookup page shows all Annex II–VI entries sharing this identifier, useful for identifying cross-annex regulatory status of the same chemical substance.

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InventoryRef 7734015/10/2010

NEOPENTYL GLYCOL DIETHYLHEXANOATE

2,2-Dimethyl-1,3-propanediyl diethylhexanoate

NEOPENTYL GLYCOL DIETHYLHEXANOATE is listed in the EU CosIng inventory, but no direct annex records are linked on this page yet.

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Regulatory evidence by market

No rule for this ingredient has been imported for any of the 13 markets tracked here.

That describes this inventory, not the law. No imported rule is not evidence that an ingredient is permitted: a rule may exist under another name or identifier, or in a dataset not yet imported here.

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Chemical identity and properties

PubChem 2D chemical structure for CAS 28510-23-8

CAS 28510-23-8PubChem CID 34260

Neopentyl Glycol Diethylhexanoate

IUPAC name: [3-(2-ethylhexanoyloxy)-2,2-dimethylpropyl] 2-ethylhexanoate

Molecular formula: C21H40O4
Molecular weight: 356.5 g/mol
Exact mass: 356.29265975 Da
XLogP3: 6.9
Topological polar surface area: 52.6 Å²
Hydrogen-bond donors: 0
Hydrogen-bond acceptors: 4
Covalent units: 1
Defined stereocentres: 0

Also known as

NEOPENTYL GLYCOL DIOCTANOATENeopentyl glycol di(2-ethylhexoate)UNII-U68ZV6W62CNeopentyl glycol di(2-ethylhexanoate)Neopentyl glycol bis(2-ethylhexanoate)U68ZV6W62CSCHERCEMOL NGDOKAK-NDO

16 more reported names

EINECS 249-060-1Hexanoic acid, 2-ethyl-, 1,1'-(2,2-dimethyl-1,3-propanediyl) esterCOSMOL 525Hexanoic acid, 2-ethyl-, 2,2-dimethyl-1,3-propanediyl esterEC 249-060-1neopentylglycol di-2-ethylhexanoateOctanoic acid, 2,2-dimethyl-1,3-propanediol diester1,3-PROPANEDIOL, 2,2-DIMETHYL-, BIS(2-ETHYLHEXANOATE)HEXANOIC ACID, 2-ETHYL-, 2,2-DIMETHYLTRIMETHYLENE ESTERRefChem:165333NEOPENTYL GLYCOL DIETHYLHEXANOATE [INCI]249-060-12,2-Dimethylpropane-1,3-diyl 2-ethylhexanoate2,2-Dimethylpropane-1,3-diyl Bis(2-ethylhexanoate)GORMSINSWZJIKL-UHFFFAOYSA-NNEOPENTYL GLYCOL, DIESTER WITH 2-ETHYLHEXANOIC ACID

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External database identifiers

EPA DTXSID:DTXSID20865431

Retrieved from NIH PubChem on 2026-08-31 by checksum-valid CAS matching. Chemical properties do not replace the regulatory decision on this page.

Inventory details for NEOPENTYL GLYCOL DIETHYLHEXANOATE

INCI name

NEOPENTYL GLYCOL DIETHYLHEXANOATE

Description

2,2-Dimethyl-1,3-propanediyl diethylhexanoate

Record provenance

Inventory reference: 77340
Imported identity: NEOPENTYL GLYCOL DIETHYLHEXANOATE
Source update: 15/10/2010

European Commission CosIng source notes

Annex records for NEOPENTYL GLYCOL DIETHYLHEXANOATE

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Key data

CAS

28510-23-8

250-575-9

Restriction

—

Function

SKIN CONDITIONING: Maintaining the skin in good condition.
SKIN CONDITIONING - EMOLLIENT: Acting as lubricants on the skin surface providing the skin with a soft and smooth appearance.

Official EU ingredient-name evidence

The ingredient name exactly matches the official 2025 EU glossary of common ingredient names.

#17338 · NEOPENTYL GLYCOL DIETHYLHEXANOATE

Ingredients with overlapping formulation functions

NEOLENTINUS LEPIDEUS/STACHYS RIEDERI ROOT EXTRACT FERMENT FILTRATESKIN CONDITIONING, SKIN CONDITIONING - EMOLLIENT

NEOPENTYL GLYCOL DICAPRATESKIN CONDITIONING, SKIN CONDITIONING - EMOLLIENT

NEOPENTYL GLYCOL DICAPRYLATE/DICAPRATESKIN CONDITIONING, SKIN CONDITIONING - EMOLLIENT

NEOPENTYL GLYCOL DICAPRYLATE/DIPELARGONATE/DICAPRATESKIN CONDITIONING, SKIN CONDITIONING - EMOLLIENT

NEOPENTYL GLYCOL DIHEPTANOATESKIN CONDITIONING, SKIN CONDITIONING - EMOLLIENT

NEOPENTYL GLYCOL DIISONONANOATESKIN CONDITIONING - EMOLLIENT

NEOPENTYL GLYCOL DIPELARGONATEPLASTICISER, SKIN CONDITIONING, SKIN CONDITIONING - EMOLLIENT, SOLVENT

NIACINAMIDOETHYL TRIPHENYLPHOSPHONIUMPENTAMIDE CHLORIDESKIN CONDITIONING - EMOLLIENT; SKIN CONDITIONING - HUMECTANT; SKIN CONDITIONING - MISCELLANEOUS; SK…

Additional official and scientific sources

11 external databases to check this identity in

Each link searches that source for this identity. What each source is, and its legal weight

ECHA CHEM / Information on chemicals PubChem PUG REST EU Safety Gate cosmetic product alerts ECHA CHEM US EPA CompTox Cosmetic Ingredient Review safety assessments FDA Global Substance Registration System ILO/WHO International Chemical Safety Cards Japan NITE-CHRIP NIOSH Pocket Guide to Chemical Hazards OECD eChemPortal

How NEOPENTYL GLYCOL DIETHYLHEXANOATE appears in the CosIng inventory

The CosIng inventory lists NEOPENTYL GLYCOL DIETHYLHEXANOATE as a cosmetic ingredient and this page links it to 0 annex records. The inventory entry captures names and identifiers, while the annex records show where the substance is prohibited, restricted or positively listed in EU cosmetics law.

NEOPENTYL GLYCOL DIETHYLHEXANOATE is also tagged with 2 cosmetic functions in the official data. Function labels describe intended use, but they do not replace regulatory review of linked annex records before formulation or labelling work.

Frequently asked questions

NEOPENTYL GLYCOL DIETHYLHEXANOATE is listed in the EU CosIng ingredient inventory with no direct annex restriction records linked at this time. Absence of an annex link does not guarantee unrestricted use — always verify against the current official CosIng database before formulating.

According to the EU CosIng inventory, NEOPENTYL GLYCOL DIETHYLHEXANOATE carries the following function designation(s):

CAS 28510-23-8 may appear across multiple EU annex records. Viewing the CAS lookup page shows all Annex II–VI entries sharing this identifier, which is useful for identifying cross-annex regulatory status of the same chemical substance.

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Source note for NEOPENTYL GLYCOL DIETHYLHEXANOATE

This page reproduces the CosIng inventory entry for NEOPENTYL GLYCOL DIETHYLHEXANOATE from public European Commission cosmetic ingredient materials and shows linked identifiers even when no direct annex match is currently attached.

Use this inventory page to research NEOPENTYL GLYCOL DIETHYLHEXANOATE and compare linked records, but verify restrictions and legal status against the current official source text and law before making regulatory decisions.

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