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CAS 127312-00-9 may appear across multiple EU annex records. The CAS lookup page shows all Annex II–VI entries sharing this identifier, useful for identifying cross-annex regulatory status of the same chemical substance.

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InventoryRef 7688715/10/2010

HYDROXYSTEARAMIDOPROPYL TRIMONIUM METHOSULFATE

1-Propanaminium, 3-[(1-oxo-12-hydroxyoctadecyl)amino]-N,N,N-trimethyl-, methyl sulfate (salt)

HYDROXYSTEARAMIDOPROPYL TRIMONIUM METHOSULFATE is listed in the EU CosIng inventory, but no direct annex records are linked on this page yet.

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Regulatory evidence by market

No rule for this ingredient has been imported for any of the 13 markets tracked here.

That describes this inventory, not the law. No imported rule is not evidence that an ingredient is permitted: a rule may exist under another name or identifier, or in a dataset not yet imported here.

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Chemical identity and properties

PubChem 2D chemical structure for CAS 127312-00-9

CAS 127312-00-9PubChem CID 57508521

Hydroxystearamidopropyl trimonium methosulfate

IUPAC name: 3-(12-hydroxyoctadecanoylamino)propyl-trimethylazanium;methyl sulfate

Molecular formula: C25H54N2O6S
Molecular weight: 510.8 g/mol
Exact mass: 510.37025862 Da
Topological polar surface area: 124.0 Å²
Hydrogen-bond donors: 2
Hydrogen-bond acceptors: 6
Covalent units: 2
Defined stereocentres: 0

Also known as

UNII-72HY9H9U1I72HY9H9U1I(+/-)-Hydroxystearamidopropyl trimonium methosulfateHydroxystearamidopropyl trimonium methosulfate, (+/-)-1-Propanaminium, 3-((12-hydroxy-1-oxooctadecyl)amino)-N,N,N-trimethyl-, methyl sulfate (Salt)3-((12-Hydroxy-1-oxooctadecyl)amino)-N,N,N-trimethyl-1-propanaminium methyl sulfate (Salt)

Open full PubChem record PubChem annotations 3D structure image

Evidence from additional scientific databases

NIH PubChem PUG-View

Exact identifier match57508521

Attributed physical-property, hazard, environmental and use annotations.

Mapped by: Existing checksum-valid CAS to unique PubChem CID match. Retrieved: 2026-08-31. Open source record

Scientific classifications and hazard annotations provide context and do not replace the market-specific regulatory decision shown above.

Additional source coverage and match status

Source	Result	Checked
NIH PubChem PUG-View	Exact match	2026-08-31

A recorded no-match is useful evidence that the source was checked; it is not a claim that the substance does not exist elsewhere.

Retrieved from NIH PubChem on 2026-08-31 by checksum-valid CAS matching. Chemical properties do not replace the regulatory decision on this page.

Inventory details for HYDROXYSTEARAMIDOPROPYL TRIMONIUM METHOSULFATE

INCI name

HYDROXYSTEARAMIDOPROPYL TRIMONIUM METHOSULFATE

Description

1-Propanaminium, 3-[(1-oxo-12-hydroxyoctadecyl)amino]-N,N,N-trimethyl-, methyl sulfate (salt)

Record provenance

Inventory reference: 76887
Imported identity: HYDROXYSTEARAMIDOPROPYL TRIMONIUM METHOSULFATE
Source update: 15/10/2010

European Commission CosIng source notes

Annex records for HYDROXYSTEARAMIDOPROPYL TRIMONIUM METHOSULFATE

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Key data

CAS

127312-00-9

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Restriction

—

Function

ANTISTATIC: Preventing and/or reducing static electricity by neutralising electrical charge on surfaces.
HAIR CONDITIONING: Enhancing the appearance and feel of hair. Leaving the hair easy to comb, supple, soft and shiny and/or imparting volume, lightness, gloss, texture, etc.

Official EU ingredient-name evidence

The ingredient name exactly matches the official 2025 EU glossary of common ingredient names.

#13411 · HYDROXYSTEARAMIDOPROPYL TRIMONIUM METHOSULFATE

Ingredients with overlapping formulation functions

HYDROXYPROPYLTRIMONIUM HYDROLYZED WHEAT STARCHANTISTATIC, HAIR CONDITIONING

HYDROXYPROPYLTRIMONIUM HYDROLYZED WHEYANTISTATIC, HAIR CONDITIONING, SKIN CONDITIONING

HYDROXYSTEARAMIDE MEAANTISTATIC, VISCOSITY CONTROLLING

HYDROXYSTEARAMIDOPROPYL TRIMONIUM CHLORIDEANTISTATIC, HAIR CONDITIONING

HYDROXYSTEARYL METHYLGLUCAMINEANTISTATIC

INOSITOLANTISTATIC, HAIR CONDITIONING, HUMECTANT

ISOBUTYL PHENYLHYDRAZINOYL METHANESULFONAMIDEANTISTATIC, UV ABSORBER

ISOBUTYLATED LANOLIN OILANTISTATIC, HAIR CONDITIONING, SKIN CONDITIONING, SKIN CONDITIONING - EMOLLIENT

Additional official and scientific sources

11 external databases to check this identity in

Each link searches that source for this identity. What each source is, and its legal weight

ECHA CHEM / Information on chemicals PubChem PUG REST EU Safety Gate cosmetic product alerts ECHA CHEM US EPA CompTox Cosmetic Ingredient Review safety assessments FDA Global Substance Registration System ILO/WHO International Chemical Safety Cards Japan NITE-CHRIP NIOSH Pocket Guide to Chemical Hazards OECD eChemPortal

How HYDROXYSTEARAMIDOPROPYL TRIMONIUM METHOSULFATE appears in the CosIng inventory

The CosIng inventory lists HYDROXYSTEARAMIDOPROPYL TRIMONIUM METHOSULFATE as a cosmetic ingredient and this page links it to 0 annex records. The inventory entry captures names and identifiers, while the annex records show where the substance is prohibited, restricted or positively listed in EU cosmetics law.

HYDROXYSTEARAMIDOPROPYL TRIMONIUM METHOSULFATE is also tagged with 2 cosmetic functions in the official data. Function labels describe intended use, but they do not replace regulatory review of linked annex records before formulation or labelling work.

Frequently asked questions

HYDROXYSTEARAMIDOPROPYL TRIMONIUM METHOSULFATE is listed in the EU CosIng ingredient inventory with no direct annex restriction records linked at this time. Absence of an annex link does not guarantee unrestricted use — always verify against the current official CosIng database before formulating.

According to the EU CosIng inventory, HYDROXYSTEARAMIDOPROPYL TRIMONIUM METHOSULFATE carries the following function designation(s):

CAS 127312-00-9 may appear across multiple EU annex records. Viewing the CAS lookup page shows all Annex II–VI entries sharing this identifier, which is useful for identifying cross-annex regulatory status of the same chemical substance.

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Source note for HYDROXYSTEARAMIDOPROPYL TRIMONIUM METHOSULFATE

This page reproduces the CosIng inventory entry for HYDROXYSTEARAMIDOPROPYL TRIMONIUM METHOSULFATE from public European Commission cosmetic ingredient materials and shows linked identifiers even when no direct annex match is currently attached.

Use this inventory page to research HYDROXYSTEARAMIDOPROPYL TRIMONIUM METHOSULFATE and compare linked records, but verify restrictions and legal status against the current official source text and law before making regulatory decisions.

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