Is CAMPHENE safe to use in EU cosmetics?

CAMPHENE is listed in the EU CosIng ingredient inventory with no direct annex restriction records linked at this time. Always verify against the current official CosIng database before formulating.

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InventoryRef 7493415/10/2010

CAMPHENE

2,2-Dimethyl-3-methylenebicyclo [2.2.1] heptane; 2,2-Dimethyl-3-methylenenorbornane; 3,3-Dimethyl-2-methylenenorcamphane

CAMPHENE is listed in the EU CosIng inventory, but no direct annex records are linked on this page yet.

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Regulatory evidence by market

No rule for this ingredient has been imported for any of the 13 markets tracked here.

That describes this inventory, not the law. No imported rule is not evidence that an ingredient is permitted: a rule may exist under another name or identifier, or in a dataset not yet imported here.

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Chemical identity and properties

PubChem 2D chemical structure for CAS 565-00-4

CAS 565-00-4PubChem CID 92221

D-Camphene

(+)-camphene is a camphene (2,2-dimethyl-3-methylenebicyclo[2.2.1]heptane) that has R configuration at position 1 and S configuration at position 4. It is an enantiomer of a (-)-camphene. — ChEBI

IUPAC name: (1R,4S)-2,2-dimethyl-3-methylidenebicyclo[2.2.1]heptane

Molecular formula: C10H16
Molecular weight: 136.23 g/mol
Exact mass: 136.125200510 Da
XLogP3: 3.3
Topological polar surface area: 0.0 Å²
Hydrogen-bond donors: 0
Hydrogen-bond acceptors: 0
Covalent units: 1
Defined stereocentres: 2

Also known as

(+)-Camphene5794-03-6Camphene, (+)-(1R,4S)-(+)-campheneCHEBI:20(1R,4S)-2,2-dimethyl-3-methylidenebicyclo(2.2.1)heptaneRefChem:1082867(1S,4R)-3,3-dimethyl-2-methylidenebicyclo(2.2.1)heptane

16 more reported names

227-336-2(+)-Comphene(1R,4S)-camphene(1R)-2,2-Dimethyl-3-methylenebicyclo[2.2.1]heptane(+)-Camphene (>90%)Bicyclo(2.2.1)heptane, 2,2-dimethyl-3-methylene-, (1R,4S)-Camphene 1000 microg/mL in Isopropanol(1R,4S)-2,2-dimethyl-3-methylene-norbornane(1R)-2,2-Dimethyl-3-methylenebicyclo(2.2.1)heptaneBicyclo[2.2.1]heptane, 2,2-dimethyl-3-methylene-, (1R,4S)-Camphene, tech gradeCamphene, 95%(A+/-)-campheneCAMPHENE, D-Camphene, >=96%, FGCamphene, analytical standard

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External database identifiers

ChEBI:CHEBI:20
ChEMBL:CHEMBL510535
EPA DTXSID:DTXSID10872336
PubMed:20964856
PubMed:16366702

Retrieved from NIH PubChem on 2026-08-31 by checksum-valid CAS matching. Chemical properties do not replace the regulatory decision on this page.

PubChem 2D chemical structure for CAS 79-92-5

CAS 79-92-5PubChem CID 6616

Camphene

Camphene is a monoterpene with a bicyclic skeleton that is bicyclo[2.2.1]heptane substituted by geminal methyl groups at position 2 and a methylidene group at position 3. It is a widespread natural product found in many essential oils. It has a role as a fragrance and a plant metabolite. It is a monoterpene and a carbobicyclic compound. — ChEBI

IUPAC name: 2,2-dimethyl-3-methylidenebicyclo[2.2.1]heptane

Molecular formula: C10H16
Molecular weight: 136.23 g/mol
Exact mass: 136.125200510 Da
XLogP3: 3.3
Topological polar surface area: 0.0 Å²
Hydrogen-bond donors: 0
Hydrogen-bond acceptors: 0
Covalent units: 1
Defined stereocentres: 0

Also known as

DL-CampheneComphene2,2-Dimethyl-3-methylenenorbornane2,2-Dimethyl-3-methylenebicyclo[2.2.1]heptane3,3-Dimethyl-2-methylenenorbornane3,3-Dimethyl-2-methylenenorcamphaneFEMA No. 2229Bicyclo[2.2.1]heptane, 2,2-dimethyl-3-methylene-

16 more reported names

G3VG94Z26EBicyclo(2.2.1)heptane, 2,2-dimethyl-3-methylene-NSC-41652,2-Dimethyl-3-methylenebicyclo(2.2.1)heptaneCHEBI:38303,3-dimethyl-2-methylidenebicyclo[2.2.1]heptane2,2-dimethyl-3-methylidenebicyclo(2.2.1)heptane3,3-dimethyl-2-methylidenebicyclo(2.2.1)heptane(A+-)-camphene(+-)-CampheneRefChem:5640201-234-8209-275-3(+/-)-Camphene2,2-dimethyl-3-methylene-norbornaneCamphene, (1R,4S)-(+)-

Open full PubChem record PubChem annotations 3D structure image

External database identifiers

ChEBI:CHEBI:3830
ChEMBL:CHEMBL2268550
EPA DTXSID:DTXSID8026488
PubMed:23724298
PubMed:23449869
PubMed:23081929
PubMed:23044111
PubMed:23039598
PubMed:23018851
PubMed:22978239
PubMed:22978237
PubMed:22835693
PubMed:22701361
PubMed:22696264
PubMed:22654405

Retrieved from NIH PubChem on 2026-08-31 by checksum-valid CAS matching. Chemical properties do not replace the regulatory decision on this page.

Inventory details for CAMPHENE

INCI name

CAMPHENE

Description

2,2-Dimethyl-3-methylenebicyclo [2.2.1] heptane; 2,2-Dimethyl-3-methylenenorbornane; 3,3-Dimethyl-2-methylenenorcamphane

Record provenance

Inventory reference: 74934
Imported identity: CAMPHENE
Source update: 15/10/2010

European Commission CosIng source notes

Annex records for CAMPHENE

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Key data

CAS

565-00-4 / 79-92-5

209-275-3 / 201-234-8

Restriction

—

Function

FRAGRANCE: Imparting an odour or taste. Creating a perceivable pleasant smell and/or masking a bad smell.

Official EU ingredient-name evidence

The ingredient name exactly matches the official 2025 EU glossary of common ingredient names.

#5169 · CAMPHENE

Ingredients with overlapping formulation functions

CAMELLIA JAPONICA SEED WATERFRAGRANCE

CAMELLIA OLEIFERA LEAFFRAGRANCE

CAMELLIA SINENSIS LEAF EXTRACTANTIMICROBIAL, ANTIOXIDANT, ASTRINGENT, FRAGRANCE, HUMECTANT, ORAL CARE, SKIN CONDITIONING, SKIN CO…

CAMELLIA SINENSIS LEAF WATERFRAGRANCE, PERFUMING, TONIC

CAMPHORDENATURANT, FRAGRANCE, PLASTICISER

CAMPHYLCYCLOHEXANOLFRAGRANCE, PERFUMING

CANANGA ODORATA FLOWER CERAFRAGRANCE, TONIC

CANANGA ODORATA FLOWER OILFRAGRANCE, PERFUMING

Additional official and scientific sources

11 external databases to check this identity in

Each link searches that source for this identity. What each source is, and its legal weight

ECHA CHEM / Information on chemicals PubChem PUG REST EU Safety Gate cosmetic product alerts ECHA CHEM US EPA CompTox Cosmetic Ingredient Review safety assessments FDA Global Substance Registration System ILO/WHO International Chemical Safety Cards Japan NITE-CHRIP NIOSH Pocket Guide to Chemical Hazards OECD eChemPortal

How CAMPHENE appears in the CosIng inventory

The CosIng inventory lists CAMPHENE as a cosmetic ingredient and this page links it to 0 annex records. The inventory entry captures names and identifiers, while the annex records show where the substance is prohibited, restricted or positively listed in EU cosmetics law.

CAMPHENE is also tagged with 1 cosmetic function in the official data. Function labels describe intended use, but they do not replace regulatory review of linked annex records before formulation or labelling work.

Frequently asked questions

CAMPHENE is listed in the EU CosIng ingredient inventory with no direct annex restriction records linked at this time. Absence of an annex link does not guarantee unrestricted use — always verify against the current official CosIng database before formulating.

According to the EU CosIng inventory, CAMPHENE carries the following function designation(s):

FRAGRANCE

CAS 565-00-4 / 79-92-5 may appear across multiple EU annex records. Viewing the CAS lookup page shows all Annex II–VI entries sharing this identifier, which is useful for identifying cross-annex regulatory status of the same chemical substance.

Use the INCI Checker to screen a full ingredient list across selected markets, or compare this substance across all supported market datasets.

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Source note for CAMPHENE

This page reproduces the CosIng inventory entry for CAMPHENE from public European Commission cosmetic ingredient materials and shows linked identifiers even when no direct annex match is currently attached.

Use this inventory page to research CAMPHENE and compare linked records, but verify restrictions and legal status against the current official source text and law before making regulatory decisions.

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Tools & next steps

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