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CAS 4386-03-2 may appear across multiple EU annex records. The CAS lookup page shows all Annex II–VI entries sharing this identifier, useful for identifying cross-annex regulatory status of the same chemical substance.

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InventoryRef 7482315/10/2010

CARBOXYETHYL AMINOBUTYRIC ACID

4-[(2-Carboxyethyl)amino]butyric acid

CARBOXYETHYL AMINOBUTYRIC ACID is listed in the EU CosIng inventory, but no direct annex records are linked on this page yet.

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Regulatory evidence by market

No rule for this ingredient has been imported for any of the 13 markets tracked here.

That describes this inventory, not the law. No imported rule is not evidence that an ingredient is permitted: a rule may exist under another name or identifier, or in a dataset not yet imported here.

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Chemical identity and properties

PubChem 2D chemical structure for CAS 4386-03-2

CAS 4386-03-2PubChem CID 2572

4-((2-Carboxyethyl)amino)butanoic acid

N-carboxyethyl-gamma-aminobutyric acid is an organonitrogen compound and an organooxygen compound. It is functionally related to a gamma-amino acid. — ChEBI

IUPAC name: 4-(2-carboxyethylamino)butanoic acid

Molecular formula: C7H13NO4
Molecular weight: 175.18 g/mol
Exact mass: 175.08445790 Da
XLogP3: -3.1
Topological polar surface area: 86.6 Å²
Hydrogen-bond donors: 3
Hydrogen-bond acceptors: 5
Covalent units: 1
Defined stereocentres: 0

Also known as

Spermidic acid4-[(2-carboxyethyl)amino]butanoic acid2-Carboxyethyl gamma-aminobutyric acidVO6U3596JPBUTANOIC ACID, 4-((2-CARBOXYETHYL)AMINO)-Butanoic acid, 4-[(2-carboxyethyl)amino]-RefChem:911961CEGABA

16 more reported names

4-(2-Carboxy-ethylamino)-butyric acidCarboxyethyl-gamma-aminobutyric acidcarboxyethyl aminobutyric acidN-Carboxyethyl-g-aminobutyric acidspermidateCarboxyethyl-GABAEINECS 224-497-04-((2-Carboxyethyl)amino)butyric acidBRN 1774240UNII-VO6U3596JPCHEBI:138529N-Carboxyethyl-gamma-aminobutyrate4-(2-Carboxy-ethylamino)-butyrateTXB-00205N-Carboxyethyl-gamma-aminobutyric acid4-((2-Carboxyethyl)amino)butanoicacid

Open full PubChem record PubChem annotations 3D structure image

External database identifiers

ChEBI:CHEBI:138529
EPA DTXSID:DTXSID80195963

Retrieved from NIH PubChem on 2026-08-31 by checksum-valid CAS matching. Chemical properties do not replace the regulatory decision on this page.

Inventory details for CARBOXYETHYL AMINOBUTYRIC ACID

INCI name

CARBOXYETHYL AMINOBUTYRIC ACID

Description

4-[(2-Carboxyethyl)amino]butyric acid

Record provenance

Inventory reference: 74823
Imported identity: CARBOXYETHYL AMINOBUTYRIC ACID
Source update: 15/10/2010

European Commission CosIng source notes

Annex records for CARBOXYETHYL AMINOBUTYRIC ACID

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Key data

CAS

4386-03-2

224-497-0

Restriction

—

Function

SKIN CONDITIONING: Maintaining the skin in good condition.

Official EU ingredient-name evidence

The ingredient name exactly matches the official 2025 EU glossary of common ingredient names.

#5473 · CARBOXYETHYL AMINOBUTYRIC ACID

Ingredients with overlapping formulation functions

CARBOCYSTEINEANTI-SEBUM, SKIN CONDITIONING

CARBONADO EXTRACTABRASIVE, SKIN CONDITIONING

CARBOXYBUTYL CHITOSANFILM FORMING, HAIR CONDITIONING, SKIN CONDITIONING, VISCOSITY CONTROLLING

CARBOXYDECYL TRISILOXANESKIN CONDITIONING, SOOTHING

CARBOXYMETHYL CHITINGEL FORMING, HAIR CONDITIONING, SKIN CONDITIONING, VISCOSITY CONTROLLING

CARBOXYMETHYL CHITOSAN SUCCINAMIDEFILM FORMING, HAIR CONDITIONING, HUMECTANT, SKIN CONDITIONING

CARBOXYMETHYL LEVANHUMECTANT, SKIN CONDITIONING

CARDAMINE FLEXUOSA EXTRACTSKIN CONDITIONING

Additional official and scientific sources

11 external databases to check this identity in

Each link searches that source for this identity. What each source is, and its legal weight

ECHA CHEM / Information on chemicals PubChem PUG REST EU Safety Gate cosmetic product alerts ECHA CHEM US EPA CompTox Cosmetic Ingredient Review safety assessments FDA Global Substance Registration System ILO/WHO International Chemical Safety Cards Japan NITE-CHRIP NIOSH Pocket Guide to Chemical Hazards OECD eChemPortal

How CARBOXYETHYL AMINOBUTYRIC ACID appears in the CosIng inventory

The CosIng inventory lists CARBOXYETHYL AMINOBUTYRIC ACID as a cosmetic ingredient and this page links it to 0 annex records. The inventory entry captures names and identifiers, while the annex records show where the substance is prohibited, restricted or positively listed in EU cosmetics law.

CARBOXYETHYL AMINOBUTYRIC ACID is also tagged with 1 cosmetic function in the official data. Function labels describe intended use, but they do not replace regulatory review of linked annex records before formulation or labelling work.

Frequently asked questions

CARBOXYETHYL AMINOBUTYRIC ACID is listed in the EU CosIng ingredient inventory with no direct annex restriction records linked at this time. Absence of an annex link does not guarantee unrestricted use — always verify against the current official CosIng database before formulating.

According to the EU CosIng inventory, CARBOXYETHYL AMINOBUTYRIC ACID carries the following function designation(s):

SKIN CONDITIONING

CAS 4386-03-2 may appear across multiple EU annex records. Viewing the CAS lookup page shows all Annex II–VI entries sharing this identifier, which is useful for identifying cross-annex regulatory status of the same chemical substance.

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Source note for CARBOXYETHYL AMINOBUTYRIC ACID

This page reproduces the CosIng inventory entry for CARBOXYETHYL AMINOBUTYRIC ACID from public European Commission cosmetic ingredient materials and shows linked identifiers even when no direct annex match is currently attached.

Use this inventory page to research CARBOXYETHYL AMINOBUTYRIC ACID and compare linked records, but verify restrictions and legal status against the current official source text and law before making regulatory decisions.

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