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CAS 506-32-1 may appear across multiple EU annex records. The CAS lookup page shows all Annex II–VI entries sharing this identifier, useful for identifying cross-annex regulatory status of the same chemical substance.

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InventoryRef 7435415/10/2010

ARACHIDONIC ACID

Icosa-5,8,11,14-tetraenoic acid

ARACHIDONIC ACID is listed in the EU CosIng inventory, but no direct annex records are linked on this page yet.

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Regulatory evidence by market

No rule for this ingredient has been imported for any of the 13 markets tracked here.

That describes this inventory, not the law. No imported rule is not evidence that an ingredient is permitted: a rule may exist under another name or identifier, or in a dataset not yet imported here.

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Chemical identity and properties

PubChem 2D chemical structure for CAS 506-32-1

CAS 506-32-1PubChem CID 444899

Arachidonic Acid

Arachidonic acid is a long-chain fatty acid that is a C20, polyunsaturated fatty acid having four (Z)-double bonds at positions 5, 8, 11 and 14. It has a role as a mouse metabolite, a human metabolite, an EC 3.1.1.1 (carboxylesterase) inhibitor and a Daphnia galeata metabolite. It is a long-chain fatty acid, an omega-6 fatty acid and an icosa-5,8,11,14-tetraenoic acid. It is a conjugate acid of an arachidonate. It derives from a hydride of a (5Z,8Z,11Z,14Z)-icosa-5,8,11,14-tetraene. — ChEBI

IUPAC name: (5Z,8Z,11Z,14Z)-icosa-5,8,11,14-tetraenoic acid

Molecular formula: C20H32O2
Molecular weight: 304.5 g/mol
Exact mass: 304.240230259 Da
XLogP3: 6.3
Topological polar surface area: 37.3 Å²
Hydrogen-bond donors: 1
Hydrogen-bond acceptors: 2
Covalent units: 1
Defined stereocentres: 0

Also known as

(all-Z)-5,8,11,14-Eicosatetraenoic acidcis-5,8,11,14-Eicosatetraenoic acid5Z,8Z,11Z,14Z-eicosatetraenoic acid5,8,11,14-Eicosatetraenoic acid, (all-Z)-all-cis-5,8,11,14-eicosatetraenoic acid27YG812J1I(5Z,8Z,11Z,14Z)-Icosatetraenoic acidC20:4

16 more reported names

CHEBI:15843Arachidonate, SodiumRefChem:5560Fatty Acid 20:4 n-6All-cis-icosa-5,8,11,14-tetraenoic acid208-033-4ImmunocytophyteUNII-27YG812J1I(5Z,8Z,11Z,14Z)-5,8,11,14-Eicosatetraenoic AcidArachidonic Acid, >97%FA 20:4(5Z,8Z,11Z,14Z)-5,8,11,14-Icosatetraenoic acid5,8,11,14-EicosatetraenoateHMS3402M21Arachidonic acid(AA)Eicosa-5Z,8Z,11Z,14Z-tetraenoic acid

Open full PubChem record PubChem annotations 3D structure image

External database identifiers

ChEBI:CHEBI:137828
ChEBI:CHEBI:15843
ChEMBL:CHEMBL15594
EPA DTXSID:DTXSID4040420
PubMed:40914282
PubMed:37353134
PubMed:33067036
PubMed:32069299
PubMed:31822559
PubMed:31575763
PubMed:31536758
PubMed:30626086
PubMed:30259074
PubMed:30258081
PubMed:29968805
PubMed:29695613

Retrieved from NIH PubChem on 2026-08-31 by checksum-valid CAS matching. Chemical properties do not replace the regulatory decision on this page.

Inventory details for ARACHIDONIC ACID

INCI name

ARACHIDONIC ACID

Description

Icosa-5,8,11,14-tetraenoic acid

Record provenance

Inventory reference: 74354
Imported identity: ARACHIDONIC ACID
Source update: 15/10/2010

European Commission CosIng source notes

Annex records for ARACHIDONIC ACID

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Key data

CAS

506-32-1

208-033-4

Restriction

—

Function

SKIN CONDITIONING: Maintaining the skin in good condition.
SKIN CONDITIONING - EMOLLIENT: Acting as lubricants on the skin surface providing the skin with a soft and smooth appearance.

Official EU ingredient-name evidence

The ingredient name exactly matches the official 2025 EU glossary of common ingredient names.

#2143 · ARACHIDONIC ACID

Ingredients with overlapping formulation functions

APRICOT KERNEL OIL POLYGLYCERYL-4 ESTERSSKIN CONDITIONING, SKIN CONDITIONING - EMOLLIENT, SURFACTANT - CLEANSING, SURFACTANT - EMULSIFYING

APRICOT KERNEL OIL POLYGLYCERYL-5 ESTERSSKIN CONDITIONING, SKIN CONDITIONING - EMOLLIENT, SURFACTANT - CLEANSING, SURFACTANT - EMULSIFYING

APRICOT KERNEL OIL POLYGLYCERYL-6 ESTERSSKIN CONDITIONING, SKIN CONDITIONING - EMOLLIENT, SURFACTANT - CLEANSING, SURFACTANT - EMULSIFYING

AQUILARIA CRASSNA STEM EXTRACTSKIN CONDITIONING, SKIN CONDITIONING - EMOLLIENT

ARACHIDYL ALCOHOLEMULSION STABILISING, SKIN CONDITIONING - EMOLLIENT, VISCOSITY CONTROLLING

ARACHIDYL BEHENATESKIN CONDITIONING, SKIN CONDITIONING - EMOLLIENT, VISCOSITY CONTROLLING

ARACHIDYL ERUCATESKIN CONDITIONING, SKIN CONDITIONING - EMOLLIENT

ARACHIDYL GLYCOL ISOSTEARATESKIN CONDITIONING, SKIN CONDITIONING - EMOLLIENT

Additional official and scientific sources

11 external databases to check this identity in

Each link searches that source for this identity. What each source is, and its legal weight

ECHA CHEM / Information on chemicals PubChem PUG REST EU Safety Gate cosmetic product alerts ECHA CHEM US EPA CompTox Cosmetic Ingredient Review safety assessments FDA Global Substance Registration System ILO/WHO International Chemical Safety Cards Japan NITE-CHRIP NIOSH Pocket Guide to Chemical Hazards OECD eChemPortal

How ARACHIDONIC ACID appears in the CosIng inventory

The CosIng inventory lists ARACHIDONIC ACID as a cosmetic ingredient and this page links it to 0 annex records. The inventory entry captures names and identifiers, while the annex records show where the substance is prohibited, restricted or positively listed in EU cosmetics law.

ARACHIDONIC ACID is also tagged with 2 cosmetic functions in the official data. Function labels describe intended use, but they do not replace regulatory review of linked annex records before formulation or labelling work.

Frequently asked questions

ARACHIDONIC ACID is listed in the EU CosIng ingredient inventory with no direct annex restriction records linked at this time. Absence of an annex link does not guarantee unrestricted use — always verify against the current official CosIng database before formulating.

According to the EU CosIng inventory, ARACHIDONIC ACID carries the following function designation(s):

CAS 506-32-1 may appear across multiple EU annex records. Viewing the CAS lookup page shows all Annex II–VI entries sharing this identifier, which is useful for identifying cross-annex regulatory status of the same chemical substance.

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Source note for ARACHIDONIC ACID

This page reproduces the CosIng inventory entry for ARACHIDONIC ACID from public European Commission cosmetic ingredient materials and shows linked identifiers even when no direct annex match is currently attached.

Use this inventory page to research ARACHIDONIC ACID and compare linked records, but verify restrictions and legal status against the current official source text and law before making regulatory decisions.

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