Is ASPARAGINE safe to use in EU cosmetics?

ASPARAGINE is listed in the EU CosIng ingredient inventory with no direct annex restriction records linked at this time. Always verify against the current official CosIng database before formulating.

What function does ASPARAGINE serve in cosmetics?

According to the EU CosIng inventory, ASPARAGINE carries the following function designation(s): ANTISTATIC, FRAGRANCE, HAIR CONDITIONING, SKIN CONDITIONING.

How do I check if my formula contains ASPARAGINE?

Use the INCI Checker to screen a full ingredient list across selected markets, or use the substance market comparison to review this identity across all supported market datasets.

InventoryRef 7433515/10/2010

ASPARAGINE

L-Asparagine

ASPARAGINE is listed in the EU CosIng inventory, but no direct annex records are linked on this page yet.

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Regulatory evidence by market

No rule for this ingredient has been imported for any of the 13 markets tracked here.

That describes this inventory, not the law. No imported rule is not evidence that an ingredient is permitted: a rule may exist under another name or identifier, or in a dataset not yet imported here.

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Chemical identity and properties

PubChem 2D chemical structure for CAS 70-47-3

CAS 70-47-3PubChem CID 6267

(-)-Asparagine

L-asparagine is an optically active form of asparagine having L-configuration. It has a role as a micronutrient, a nutraceutical, a mouse metabolite, a Saccharomyces cerevisiae metabolite, a plant metabolite, an Escherichia coli metabolite and a human metabolite. It is a L-alpha-amino acid, an asparagine, an aspartate family amino acid and a proteinogenic amino acid. It is a conjugate base of a L-asparaginium. It is a conjugate acid of a L-asparaginate. It is an enantiomer of a D-asparagine. It is a tautomer of a L-asparagine zwitterion. — ChEBI

IUPAC name: (2S)-2,4-diamino-4-oxobutanoic acid

Molecular formula: C4H8N2O3
Molecular weight: 132.12 g/mol
Exact mass: 132.05349212 Da
XLogP3: -3.4
Topological polar surface area: 106.0 Å²
Hydrogen-bond donors: 3
Hydrogen-bond acceptors: 4
Covalent units: 1
Defined stereocentres: 1

Also known as

L-asparagineasparagineAspartamic acid(S)-asparagineagedoitealtheineAsparamideCrystal VI

16 more reported names

asparagine acid(S)-2,4-diamino-4-oxobutanoic acidL-Aspartaminealpha-aminosuccinamic acidL-Asparagine anhydrous2-Aminosuccinamic acidaspartic acid beta-amideL-2,4-diamino-4-oxobutanoic acid(2S)-2-amino-3-carbamoylpropanoic acidAspartic acid amideL-2-aminosuccinamic acidAsparagine anhydrousL-Asn2-aminosuccinamic acid, L-butanoic acid, 2,4-diamino-4-oxo-, (S)-L-Asparagin

Open full PubChem record PubChem annotations 3D structure image

External database identifiers

ChEBI:CHEBI:17196
ChEMBL:CHEMBL58832
EPA DTXSID:DTXSID10883220
PubMed:29968805
PubMed:23118975
PubMed:23113336
PubMed:23100688
PubMed:23098298
PubMed:23094515
PubMed:23094070
PubMed:23053196
PubMed:23051772
PubMed:23051710
PubMed:23049690
PubMed:23046062

Retrieved from NIH PubChem on 2026-08-31 by checksum-valid CAS matching. Chemical properties do not replace the regulatory decision on this page.

Inventory details for ASPARAGINE

INCI name

ASPARAGINE

Description

L-Asparagine

Record provenance

Inventory reference: 74335
Imported identity: ASPARAGINE
Source update: 15/10/2010

European Commission CosIng source notes

Annex records for ASPARAGINE

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Key data

CAS

70-47-3 / 3130-87-8

200-735-9 / 221-521-1

Restriction

—

Function

ANTISTATIC: Preventing and/or reducing static electricity by neutralising electrical charge on surfaces.
FRAGRANCE: Imparting an odour or taste. Creating a perceivable pleasant smell and/or masking a bad smell.
HAIR CONDITIONING: Enhancing the appearance and feel of hair. Leaving the hair easy to comb, supple, soft and shiny and/or imparting volume, lightness, gloss, texture, etc.
SKIN CONDITIONING: Maintaining the skin in good condition.

Official EU ingredient-name evidence

The ingredient name exactly matches the official 2025 EU glossary of common ingredient names.

#2453 · ASPARAGINE

Ingredients with overlapping formulation functions

AMP-ISOSTEAROYL HYDROLYZED COLLAGENANTISTATIC, CLEANSING, HAIR CONDITIONING, SKIN CONDITIONING, SKIN CONDITIONING - EMOLLIENT, SURFACT…

APRICOTAMIDOPROPYL BETAINEANTISTATIC, CLEANSING, HAIR CONDITIONING, SKIN CONDITIONING, SURFACTANT - CLEANSING, SURFACTANT - F…

APRICOTAMIDOPROPYL ETHYLDIMONIUM ETHOSULFATEANTISTATIC, HAIR CONDITIONING, SKIN CONDITIONING

ARGININEANTISTATIC, FRAGRANCE, HAIR CONDITIONING, SKIN CONDITIONING

ASPARTIC ACIDANTISTATIC, FRAGRANCE, HAIR CONDITIONING, SKIN CONDITIONING

AURANTIOCHYTRIUM LIMACINUM OILANTISTATIC, SKIN CONDITIONING, SKIN CONDITIONING - EMOLLIENT

AVOCADAMIDOPROPALKONIUM CHLORIDEANTISTATIC

AVOCADAMIDOPROPYL BETAINEANTISTATIC, CLEANSING, HAIR CONDITIONING, SKIN CONDITIONING, SURFACTANT - CLEANSING, SURFACTANT - F…

Additional official and scientific sources

11 external databases to check this identity in

Each link searches that source for this identity. What each source is, and its legal weight

ECHA CHEM / Information on chemicals PubChem PUG REST EU Safety Gate cosmetic product alerts ECHA CHEM US EPA CompTox Cosmetic Ingredient Review safety assessments FDA Global Substance Registration System ILO/WHO International Chemical Safety Cards Japan NITE-CHRIP NIOSH Pocket Guide to Chemical Hazards OECD eChemPortal

How ASPARAGINE appears in the CosIng inventory

The CosIng inventory lists ASPARAGINE as a cosmetic ingredient and this page links it to 0 annex records. The inventory entry captures names and identifiers, while the annex records show where the substance is prohibited, restricted or positively listed in EU cosmetics law.

ASPARAGINE is also tagged with 4 cosmetic functions in the official data. Function labels describe intended use, but they do not replace regulatory review of linked annex records before formulation or labelling work.

Frequently asked questions

ASPARAGINE is listed in the EU CosIng ingredient inventory with no direct annex restriction records linked at this time. Absence of an annex link does not guarantee unrestricted use — always verify against the current official CosIng database before formulating.

According to the EU CosIng inventory, ASPARAGINE carries the following function designation(s):

CAS 70-47-3 / 3130-87-8 may appear across multiple EU annex records. Viewing the CAS lookup page shows all Annex II–VI entries sharing this identifier, which is useful for identifying cross-annex regulatory status of the same chemical substance.

Use the INCI Checker to screen a full ingredient list across selected markets, or compare this substance across all supported market datasets.

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Source note for ASPARAGINE

This page reproduces the CosIng inventory entry for ASPARAGINE from public European Commission cosmetic ingredient materials and shows linked identifiers even when no direct annex match is currently attached.

Use this inventory page to research ASPARAGINE and compare linked records, but verify restrictions and legal status against the current official source text and law before making regulatory decisions.

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Tools & next steps

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