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InventoryRef 7399415/10/2010

ACETYLATED CETYL HYDROXYPROLINATE

L-Proline, 1-acetyl-4-(acetyloxy)-, hexadecyl ester, (4R)-

ACETYLATED CETYL HYDROXYPROLINATE is listed in the EU CosIng inventory, but no direct annex records are linked on this page yet.

Regulatory evidence by market

No rule for this ingredient has been imported for any of the 13 markets tracked here.

That describes this inventory, not the law. No imported rule is not evidence that an ingredient is permitted: a rule may exist under another name or identifier, or in a dataset not yet imported here.

Chemical identity and properties

PubChem 2D chemical structure for CAS 221378-54-7
CAS 221378-54-7PubChem CID 101603178

1-Acetyl-4-acetoxyproline, cetyl ester

IUPAC name
hexadecyl (2S)-1-acetyl-4-acetyloxypyrrolidine-2-carboxylate
Molecular formula
C25H45NO5
Molecular weight
439.6 g/mol
Exact mass
439.32977354 Da
XLogP3
7.5
Topological polar surface area
72.9 Ų
Hydrogen-bond donors
0
Hydrogen-bond acceptors
5
Covalent units
1
Defined stereocentres
1

Also known as

VGMBKAGMLBFALV-CGAIIQECSA-N
External database identifiers

Retrieved from NIH PubChem on 2026-08-31 by checksum-valid CAS matching. Chemical properties do not replace the regulatory decision on this page.

Inventory details for ACETYLATED CETYL HYDROXYPROLINATE

INCI name

ACETYLATED CETYL HYDROXYPROLINATE

Description

L-Proline, 1-acetyl-4-(acetyloxy)-, hexadecyl ester, (4R)-

Record provenance

Inventory reference
73994
Imported identity
ACETYLATED CETYL HYDROXYPROLINATE
Source update
15/10/2010
European Commission CosIng source notes

Key data

EC
Restriction
Function
SKIN CONDITIONING
Maintaining the skin in good condition.
SKIN CONDITIONING - EMOLLIENT
Acting as lubricants on the skin surface providing the skin with a soft and smooth appearance.

Official EU ingredient-name evidence

The ingredient name exactly matches the official 2025 EU glossary of common ingredient names.

Ingredients with overlapping formulation functions

Additional official and scientific sources

11 external databases to check this identity in

How ACETYLATED CETYL HYDROXYPROLINATE appears in the CosIng inventory

The CosIng inventory lists ACETYLATED CETYL HYDROXYPROLINATE as a cosmetic ingredient and this page links it to 0 annex records. The inventory entry captures names and identifiers, while the annex records show where the substance is prohibited, restricted or positively listed in EU cosmetics law.

ACETYLATED CETYL HYDROXYPROLINATE is also tagged with 2 cosmetic functions in the official data. Function labels describe intended use, but they do not replace regulatory review of linked annex records before formulation or labelling work.

Frequently asked questions

ACETYLATED CETYL HYDROXYPROLINATE is listed in the EU CosIng ingredient inventory with no direct annex restriction records linked at this time. Absence of an annex link does not guarantee unrestricted use — always verify against the current official CosIng database before formulating.

According to the EU CosIng inventory, ACETYLATED CETYL HYDROXYPROLINATE carries the following function designation(s):

CAS 221378-54-7 may appear across multiple EU annex records. Viewing the CAS lookup page shows all Annex II–VI entries sharing this identifier, which is useful for identifying cross-annex regulatory status of the same chemical substance.

Use the INCI Checker to screen a full ingredient list across selected markets, or compare this substance across all supported market datasets.

Source note for ACETYLATED CETYL HYDROXYPROLINATE

This page reproduces the CosIng inventory entry for ACETYLATED CETYL HYDROXYPROLINATE from public European Commission cosmetic ingredient materials and shows linked identifiers even when no direct annex match is currently attached.

Use this inventory page to research ACETYLATED CETYL HYDROXYPROLINATE and compare linked records, but verify restrictions and legal status against the current official source text and law before making regulatory decisions.

Tools & next steps

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