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CAS 537-55-3 may appear across multiple EU annex records. The CAS lookup page shows all Annex II–VI entries sharing this identifier, useful for identifying cross-annex regulatory status of the same chemical substance.

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InventoryRef 7399215/10/2010

ACETYL TYROSINE

N-acetyl-L-tyrosine

ACETYL TYROSINE is listed in the EU CosIng inventory, but no direct annex records are linked on this page yet.

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Regulatory evidence by market

No rule for this ingredient has been imported for any of the 13 markets tracked here.

That describes this inventory, not the law. No imported rule is not evidence that an ingredient is permitted: a rule may exist under another name or identifier, or in a dataset not yet imported here.

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Chemical identity and properties

PubChem 2D chemical structure for CAS 537-55-3

CAS 537-55-3PubChem CID 68310

N-Acetyl-L-tyrosine

N-acetyl-L-tyrosine is an N-acetyltyrosine in which the chiral centre has L configuration. It has a role as a biomarker, an EC 2.1.1.4 (acetylserotonin O-methyltransferase) inhibitor and a human urinary metabolite. It is a N-acetyltyrosine and a N-acyl-L-tyrosine. It is a conjugate acid of a N-acetyl-L-tyrosinate. — ChEBI

IUPAC name: (2S)-2-acetamido-3-(4-hydroxyphenyl)propanoic acid

Molecular formula: C11H13NO4
Molecular weight: 223.22 g/mol
Exact mass: 223.08445790 Da
XLogP3: -0.2
Topological polar surface area: 86.6 Å²
Hydrogen-bond donors: 3
Hydrogen-bond acceptors: 4
Covalent units: 1
Defined stereocentres: 1

Also known as

N-AcetyltyrosineAcetyl tyrosineL-Tyrosine, N-acetyl-L-Tyrosine, acetyl-N-Acetyltyrosine (VAN)UNII-DA8G610ZO5L-N-acetyl-TyrosineTANOGEN HB

16 more reported names

TYR-EXCELACETYL L-TYROSINEEINECS 208-671-3NSC 10853Tyrosine, N-acetyl-, L-L-TYROSINE, N-ACETYLN-ACETYL-L-TYROSINE [USP-RS]N-ACETYLTYROSINE [EP MONOGRAPH](2S)-2-(acetylamino)-3-(4-hydroxyphenyl)propanoic acid(2S)-2-Acetylamino-3-(4-hydroxyphenyl)propanoateNSC-10853N-ACETYL-L-TYROSINE (USP-RS)N-ACETYLTYROSINE (EP MONOGRAPH)CHEBI:685612-(acetylamino)-3-(4-hydroxyphenyl)propanoic acidRefChem:162624

Open full PubChem record PubChem annotations 3D structure image

External database identifiers

ChEBI:CHEBI:21563
ChEMBL:CHEMBL65543
EPA DTXSID:DTXSID7046045
PubMed:22969507
PubMed:22477801
PubMed:21793504
PubMed:21401647
PubMed:21365350
PubMed:21210840
PubMed:20549514
PubMed:20049071
PubMed:20049070
PubMed:19658383
PubMed:19177191
PubMed:19158988

Retrieved from NIH PubChem on 2026-08-31 by checksum-valid CAS matching. Chemical properties do not replace the regulatory decision on this page.

Inventory details for ACETYL TYROSINE

INCI name

ACETYL TYROSINE

Description

N-acetyl-L-tyrosine

Record provenance

Inventory reference: 73992
Imported identity: ACETYL TYROSINE
Source update: 15/10/2010

European Commission CosIng source notes

Annex records for ACETYL TYROSINE

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Key data

CAS

537-55-3

208-671-3

Restriction

—

Function

SKIN CONDITIONING: Maintaining the skin in good condition.
TANNING: Darkening the skin with or without exposure to UV.

Official EU ingredient-name evidence

The ingredient name exactly matches the official 2025 EU glossary of common ingredient names.

#780 · ACETYL TYROSINE

Ingredients with overlapping formulation functions

DIHYDROXYACETONEHAIR DYEING, SKIN CONDITIONING - MISCELLANEOUS, TANNING

ERYTHRULOSETANNING

Additional official and scientific sources

11 external databases to check this identity in

Each link searches that source for this identity. What each source is, and its legal weight

ECHA CHEM / Information on chemicals PubChem PUG REST EU Safety Gate cosmetic product alerts ECHA CHEM US EPA CompTox Cosmetic Ingredient Review safety assessments FDA Global Substance Registration System ILO/WHO International Chemical Safety Cards Japan NITE-CHRIP NIOSH Pocket Guide to Chemical Hazards OECD eChemPortal

How ACETYL TYROSINE appears in the CosIng inventory

The CosIng inventory lists ACETYL TYROSINE as a cosmetic ingredient and this page links it to 0 annex records. The inventory entry captures names and identifiers, while the annex records show where the substance is prohibited, restricted or positively listed in EU cosmetics law.

ACETYL TYROSINE is also tagged with 2 cosmetic functions in the official data. Function labels describe intended use, but they do not replace regulatory review of linked annex records before formulation or labelling work.

Frequently asked questions

ACETYL TYROSINE is listed in the EU CosIng ingredient inventory with no direct annex restriction records linked at this time. Absence of an annex link does not guarantee unrestricted use — always verify against the current official CosIng database before formulating.

According to the EU CosIng inventory, ACETYL TYROSINE carries the following function designation(s):

CAS 537-55-3 may appear across multiple EU annex records. Viewing the CAS lookup page shows all Annex II–VI entries sharing this identifier, which is useful for identifying cross-annex regulatory status of the same chemical substance.

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Source note for ACETYL TYROSINE

This page reproduces the CosIng inventory entry for ACETYL TYROSINE from public European Commission cosmetic ingredient materials and shows linked identifiers even when no direct annex match is currently attached.

Use this inventory page to research ACETYL TYROSINE and compare linked records, but verify restrictions and legal status against the current official source text and law before making regulatory decisions.

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