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CAS 164462-16-2 may appear across multiple EU annex records. The CAS lookup page shows all Annex II–VI entries sharing this identifier, useful for identifying cross-annex regulatory status of the same chemical substance.

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InventoryRef 5988815/10/2010

TRISODIUM DICARBOXYMETHYL ALANINATE

2-Aminopropionic acid, N,N-dicarboxymethyl-, trisodium salt

TRISODIUM DICARBOXYMETHYL ALANINATE is listed in the EU CosIng inventory, but no direct annex records are linked on this page yet.

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Regulatory evidence by market

No rule for this ingredient has been imported for any of the 13 markets tracked here.

That describes this inventory, not the law. No imported rule is not evidence that an ingredient is permitted: a rule may exist under another name or identifier, or in a dataset not yet imported here.

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Chemical identity and properties

PubChem 2D chemical structure for CAS 164462-16-2

CAS 164462-16-2PubChem CID 11021984

Trisodium dicarboxymethyl alaninate

IUPAC name: trisodium;2-[bis(carboxylatomethyl)amino]propanoate

Molecular formula: C7H8NNa3O6
Molecular weight: 271.11 g/mol
Exact mass: 271.00446982 Da
Topological polar surface area: 124.0 Å²
Hydrogen-bond donors: 0
Hydrogen-bond acceptors: 7
Covalent units: 4
Defined stereocentres: 0

Also known as

UNII-784K2O81WYTrisodium dicarboxymethylalaninate784K2O81WYAlanine, N,N-bis(carboxymethyl)-, trisodium saltDL-Alanine-N,N-diacetic acid trisodium saltTRISODIUM DICARBOXYMETHYL ALANINATE, DL-Alanine, N-N-bis(carboxymethyl)-, trisodium saltDL-ALANINE, N,N-BIS(CARBOXYMETHYL)-, TRISODIUM SALT

16 more reported names

RefChem:192168TRISODIUM DICARBOXYMETHYL ALANINATE [INCI]605-362-9Trisodium N-(1-Carboxylatoethyl)iminodiacetateAlanine, N,N-bis(carboxymethyl)-, sodium salt (1:3)Trisodium 2-[bis(carboxymethyl)amino]propanoateTrisodiuM N-(1-Carboxylatoethyl)iMinodiacetate HydrateC7H8NNa3O6Trisodium 2-MethylnitrilotriacetateMGDAMethyl glycine diacetic acid trisodium saltN,N-Bis(carboxylatomethyl)alanine Trisodium SaltOHOTVSOGTVKXEL-UHFFFAOYSA-KTrisodium Dicarboxymethyl DL-AlaninateCS-0217447N,N-Bis(carboxymethyl)alanine trisodium salt

Open full PubChem record PubChem annotations 3D structure image

External database identifiers

EPA DTXSID:DTXSID2044555

Retrieved from NIH PubChem on 2026-08-31 by checksum-valid CAS matching. Chemical properties do not replace the regulatory decision on this page.

Inventory details for TRISODIUM DICARBOXYMETHYL ALANINATE

INCI name

TRISODIUM DICARBOXYMETHYL ALANINATE

Description

2-Aminopropionic acid, N,N-dicarboxymethyl-, trisodium salt

Record provenance

Inventory reference: 59888
Imported identity: TRISODIUM DICARBOXYMETHYL ALANINATE
Source update: 15/10/2010

European Commission CosIng source notes

Annex records for TRISODIUM DICARBOXYMETHYL ALANINATE

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Key data

CAS

164462-16-2

—

Restriction

—

Function

CHELATING: Forming complexes with metal ions which could affect the stability and/or appearance of cosmetics.

Official EU ingredient-name evidence

The ingredient name exactly matches the official 2025 EU glossary of common ingredient names.

#29467 · TRISODIUM DICARBOXYMETHYL ALANINATE

Ingredients with overlapping formulation functions

TRIMETHOXYBENZYLIDENE PENTANEDIONEANTIOXIDANT, CHELATING, SKIN PROTECTING

TRIMETHYLDECENEDIONEBLEACHING, CHELATING

TRIMETHYLOLPROPANE HYDROXYPROPYL BIS-HYDROXYETHYLAMINE DENDRIMERCHELATING, CLEANSING, SURFACTANT - CLEANSING

TRIPOTASSIUM EDTACHELATING

TRISODIUM EDTACHELATING

TRISODIUM ETHYLENEDIAMINE DISUCCINATECHELATING

TRISODIUM FRUCTOSE DIPHOSPHATEANTIOXIDANT, CHELATING

TRISODIUM HEDTACHELATING

Additional official and scientific sources

11 external databases to check this identity in

Each link searches that source for this identity. What each source is, and its legal weight

ECHA CHEM / Information on chemicals PubChem PUG REST EU Safety Gate cosmetic product alerts ECHA CHEM US EPA CompTox Cosmetic Ingredient Review safety assessments FDA Global Substance Registration System ILO/WHO International Chemical Safety Cards Japan NITE-CHRIP NIOSH Pocket Guide to Chemical Hazards OECD eChemPortal

How TRISODIUM DICARBOXYMETHYL ALANINATE appears in the CosIng inventory

The CosIng inventory lists TRISODIUM DICARBOXYMETHYL ALANINATE as a cosmetic ingredient and this page links it to 0 annex records. The inventory entry captures names and identifiers, while the annex records show where the substance is prohibited, restricted or positively listed in EU cosmetics law.

TRISODIUM DICARBOXYMETHYL ALANINATE is also tagged with 1 cosmetic function in the official data. Function labels describe intended use, but they do not replace regulatory review of linked annex records before formulation or labelling work.

Frequently asked questions

TRISODIUM DICARBOXYMETHYL ALANINATE is listed in the EU CosIng ingredient inventory with no direct annex restriction records linked at this time. Absence of an annex link does not guarantee unrestricted use — always verify against the current official CosIng database before formulating.

According to the EU CosIng inventory, TRISODIUM DICARBOXYMETHYL ALANINATE carries the following function designation(s):

CHELATING

CAS 164462-16-2 may appear across multiple EU annex records. Viewing the CAS lookup page shows all Annex II–VI entries sharing this identifier, which is useful for identifying cross-annex regulatory status of the same chemical substance.

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Source note for TRISODIUM DICARBOXYMETHYL ALANINATE

This page reproduces the CosIng inventory entry for TRISODIUM DICARBOXYMETHYL ALANINATE from public European Commission cosmetic ingredient materials and shows linked identifiers even when no direct annex match is currently attached.

Use this inventory page to research TRISODIUM DICARBOXYMETHYL ALANINATE and compare linked records, but verify restrictions and legal status against the current official source text and law before making regulatory decisions.

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Tools & next steps

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