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CAS 538-43-2 may appear across multiple EU annex records. The CAS lookup page shows all Annex II–VI entries sharing this identifier, useful for identifying cross-annex regulatory status of the same chemical substance.

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InventoryRef 5921115/10/2010

PHENOXYPROPANEDIOL

1,2-Propanediol, 3-phenoxy-

PHENOXYPROPANEDIOL is listed in the EU CosIng inventory, but no direct annex records are linked on this page yet.

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Regulatory evidence by market

No rule for this ingredient has been imported for any of the 13 markets tracked here.

That describes this inventory, not the law. No imported rule is not evidence that an ingredient is permitted: a rule may exist under another name or identifier, or in a dataset not yet imported here.

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Chemical identity and properties

PubChem 2D chemical structure for CAS 538-43-2

CAS 538-43-2PubChem CID 10857

3-Phenoxy-1,2-propanediol

IUPAC name: 3-phenoxypropane-1,2-diol

Molecular formula: C9H12O3
Molecular weight: 168.19 g/mol
Exact mass: 168.078644241 Da
XLogP3: 0.7
Topological polar surface area: 49.7 Å²
Hydrogen-bond donors: 2
Hydrogen-bond acceptors: 3
Covalent units: 1
Defined stereocentres: 0

Also known as

AntodynePhenylglyceryl ether1,2-Propanediol, 3-phenoxy-Phenol glyceryl etherAntodynPhenol glycerol ether1-Phenoxy-2,3-propanediolphenoxypropanediol

16 more reported names

Glycerol alpha-monophenyl etherGlycerol alpha-phenyl ether38D39W41IJU 27,462NSC-406489PHENOXY PROPANEDIOL 816430RefChem:861737208-692-8Phenol-glycerinaether1-Fenoxy-2,3-propandiolphenylglycerolEINECS 208-692-8Glycerol .alpha.-phenyl etherNSC 406489BRN 1869155Glycerol .alpha.-monophenyl ether

Open full PubChem record PubChem annotations 3D structure image

External database identifiers

EPA DTXSID:DTXSID90870597
PubMed:22442595
PubMed:22102494
PubMed:21479833
PubMed:21159331
PubMed:20471590
PubMed:18767134
PubMed:17710393
PubMed:16634127
PubMed:15094358
PubMed:12910978
PubMed:12856132

Retrieved from NIH PubChem on 2026-08-31 by checksum-valid CAS matching. Chemical properties do not replace the regulatory decision on this page.

Inventory details for PHENOXYPROPANEDIOL

INCI name

PHENOXYPROPANEDIOL

Description

1,2-Propanediol, 3-phenoxy-

Record provenance

Inventory reference: 59211
Imported identity: PHENOXYPROPANEDIOL
Source update: 15/10/2010

European Commission CosIng source notes

Annex records for PHENOXYPROPANEDIOL

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Key data

CAS

538-43-2

208-692-8

Restriction

—

Function

SOLVENT: Dissolving other components of cosmetics. Solvents are usually liquids (aqueous and nonaqueous).

Official EU ingredient-name evidence

The ingredient name exactly matches the official 2025 EU glossary of common ingredient names.

#20716 · PHENOXYPROPANEDIOL

Ingredients with overlapping formulation functions

PERFLUOROPERHYDROPHENANTHRENESKIN CONDITIONING, SOLVENT

PERFLUOROTETRALINDETANGLING, SKIN CONDITIONING, SOLVENT

PETROLEUM DISTILLATESANTIFOAMING, SOLVENT

PHENOXYISOPROPANOLPRESERVATIVE, SOLVENT

PHENYLPROPANESOLVENT

PHENYLPROPANOLFRAGRANCE, PERFUMING, SOLVENT

PHOSPHATE BUFFERED SALINESOLVENT

PIG PLACENTA WATERHUMECTANT; SOLVENT; SKIN CONDITIONING - MISCELLANEOUS

Additional official and scientific sources

11 external databases to check this identity in

Each link searches that source for this identity. What each source is, and its legal weight

ECHA CHEM / Information on chemicals PubChem PUG REST EU Safety Gate cosmetic product alerts ECHA CHEM US EPA CompTox Cosmetic Ingredient Review safety assessments FDA Global Substance Registration System ILO/WHO International Chemical Safety Cards Japan NITE-CHRIP NIOSH Pocket Guide to Chemical Hazards OECD eChemPortal

How PHENOXYPROPANEDIOL appears in the CosIng inventory

The CosIng inventory lists PHENOXYPROPANEDIOL as a cosmetic ingredient and this page links it to 0 annex records. The inventory entry captures names and identifiers, while the annex records show where the substance is prohibited, restricted or positively listed in EU cosmetics law.

PHENOXYPROPANEDIOL is also tagged with 1 cosmetic function in the official data. Function labels describe intended use, but they do not replace regulatory review of linked annex records before formulation or labelling work.

Frequently asked questions

PHENOXYPROPANEDIOL is listed in the EU CosIng ingredient inventory with no direct annex restriction records linked at this time. Absence of an annex link does not guarantee unrestricted use — always verify against the current official CosIng database before formulating.

According to the EU CosIng inventory, PHENOXYPROPANEDIOL carries the following function designation(s):

SOLVENT

CAS 538-43-2 may appear across multiple EU annex records. Viewing the CAS lookup page shows all Annex II–VI entries sharing this identifier, which is useful for identifying cross-annex regulatory status of the same chemical substance.

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Source note for PHENOXYPROPANEDIOL

This page reproduces the CosIng inventory entry for PHENOXYPROPANEDIOL from public European Commission cosmetic ingredient materials and shows linked identifiers even when no direct annex match is currently attached.

Use this inventory page to research PHENOXYPROPANEDIOL and compare linked records, but verify restrictions and legal status against the current official source text and law before making regulatory decisions.

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