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CAS 91722-21-3 may appear across multiple EU annex records. The CAS lookup page shows all Annex II–VI entries sharing this identifier, useful for identifying cross-annex regulatory status of the same chemical substance.

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InventoryRef 5882115/10/2010

STEVIA REBAUDIANA LEAF/STEM EXTRACT

Stevia Rebaudiana Leaf/Stem Extract Is an extract of the leaves and stems of the Stevia rebaudiana, Asteraceae

STEVIA REBAUDIANA LEAF/STEM EXTRACT is listed in the EU CosIng inventory, but no direct annex records are linked on this page yet.

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Regulatory evidence by market

No rule for this ingredient has been imported for any of the 13 markets tracked here.

That describes this inventory, not the law. No imported rule is not evidence that an ingredient is permitted: a rule may exist under another name or identifier, or in a dataset not yet imported here.

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Chemical identity and properties

PubChem 2D chemical structure for CAS 91722-21-3

CAS 91722-21-3PubChem CID 13370031

Stevia rebaudiana, ext.

Stevia rebaudiana, ext. has been reported in Stevia rebaudiana with data available. — LOTUS - the natural products occurrence database

IUPAC name: [3,4,5-trihydroxy-6-(hydroxymethyl)oxan-2-yl] 13-[5-hydroxy-6-(hydroxymethyl)-3,4-bis[[3,4,5-trihydroxy-6-(hydroxymethyl)oxan-2-yl]oxy]oxan-2-yl]oxy-5,9-dimethyl-14-methylidenetetracyclo[11.2.1.01,10.04,9]hexadecane-5-carboxylate

Molecular formula: C44H70O23
Molecular weight: 967.0 g/mol
Exact mass: 966.43078848 Da
XLogP3: -2.8
Topological polar surface area: 374.0 Å²
Hydrogen-bond donors: 14
Hydrogen-bond acceptors: 23
Covalent units: 1
Defined stereocentres: 0

Also known as

SweetleafStevia rebaudiana, extRefChem:185726EINECS 294-422-4Stevia (Stevia rebaudiana) Extract or Powder294-422-4Lebaldide AC44H70O23

5 more reported names

Open full PubChem record PubChem annotations 3D structure image

Retrieved from NIH PubChem on 2026-08-31 by checksum-valid CAS matching. Chemical properties do not replace the regulatory decision on this page.

What the official INCI name states

The official label is a composite INCI name with 2 named source-material segments. Each segment must be reconciled with the supplier specification.

Identity type from wording: composite
Preparation or form: STEM EXTRACT, EXTRACT
Stated biological parts: LEAF, STEM
Named source segments: 2

Review parsed source-name segments

STEVIA REBAUDIANA LEAF
STEM EXTRACT

Scientific-name candidates to verify against the supplier specification

Stevia rebaudiana

This structure is derived only from the official label wording. It does not establish composition, concentration, chemical equivalence, safety or regulatory permission.

Inventory details for STEVIA REBAUDIANA LEAF/STEM EXTRACT

INCI name

STEVIA REBAUDIANA LEAF/STEM EXTRACT

Description

Stevia Rebaudiana Leaf/Stem Extract Is an extract of the leaves and stems of the Stevia rebaudiana, Asteraceae

Record provenance

Inventory reference: 58821
Imported identity: STEVIA REBAUDIANA LEAF/STEM EXTRACT
Source update: 15/10/2010

European Commission CosIng source notes

Annex records for STEVIA REBAUDIANA LEAF/STEM EXTRACT

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Key data

CAS

91722-21-3

294-422-4

Restriction

—

Function

FRAGRANCE: Imparting an odour or taste. Creating a perceivable pleasant smell and/or masking a bad smell.

Official EU ingredient-name evidence

The ingredient name exactly matches the official 2025 EU glossary of common ingredient names.

#27909 · STEVIA REBAUDIANA LEAF/STEM EXTRACT

Other ingredients from the same source

Stevia rebaudiana

7 other ingredients in this inventory name the same organism. Sharing a source is not sharing an identity: a leaf extract, a seed oil and a ferment are different materials with different specifications.

Records sharing a CAS or EC identity

STEVIA REBAUDIANA EXTRACT

Ingredients with overlapping formulation functions

STEARIC ACIDCLEANSING, EMULSION STABILISING, FRAGRANCE, REFATTING, SURFACTANT - CLEANSING, SURFACTANT - EMULSIF…

STEARYL ALCOHOLEMULSION STABILISING, FRAGRANCE, OPACIFYING, REFATTING, SKIN CONDITIONING - EMOLLIENT, SURFACTANT -…

STEMONA SESSIFOLIA ROOT POWDERABRASIVE, FRAGRANCE, SKIN PROTECTING

STERCULIA URENS GUMBINDING, EMULSION STABILISING, FRAGRANCE, HAIR FIXING, VISCOSITY CONTROLLING

STEVIOSIDEFRAGRANCE, ORAL CARE

STYRAX BENZOIN GUMFILM FORMING, FRAGRANCE, PERFUMING, SKIN CONDITIONING

STYRAX BENZOIN RESIN EXTRACTFILM FORMING, FRAGRANCE, PERFUMING

SUCCINIC ACIDBUFFERING, FRAGRANCE

Additional official and scientific sources

11 external databases to check this identity in

Each link searches that source for this identity. What each source is, and its legal weight

ECHA CHEM / Information on chemicals PubChem PUG REST EU Safety Gate cosmetic product alerts ECHA CHEM US EPA CompTox Cosmetic Ingredient Review safety assessments FDA Global Substance Registration System ILO/WHO International Chemical Safety Cards Japan NITE-CHRIP NIOSH Pocket Guide to Chemical Hazards OECD eChemPortal

How STEVIA REBAUDIANA LEAF/STEM EXTRACT appears in the CosIng inventory

The CosIng inventory lists STEVIA REBAUDIANA LEAF/STEM EXTRACT as a cosmetic ingredient and this page links it to 0 annex records. The inventory entry captures names and identifiers, while the annex records show where the substance is prohibited, restricted or positively listed in EU cosmetics law.

STEVIA REBAUDIANA LEAF/STEM EXTRACT is also tagged with 1 cosmetic function in the official data. Function labels describe intended use, but they do not replace regulatory review of linked annex records before formulation or labelling work.

Frequently asked questions

STEVIA REBAUDIANA LEAF/STEM EXTRACT is listed in the EU CosIng ingredient inventory with no direct annex restriction records linked at this time. Absence of an annex link does not guarantee unrestricted use — always verify against the current official CosIng database before formulating.

According to the EU CosIng inventory, STEVIA REBAUDIANA LEAF/STEM EXTRACT carries the following function designation(s):

FRAGRANCE

CAS 91722-21-3 may appear across multiple EU annex records. Viewing the CAS lookup page shows all Annex II–VI entries sharing this identifier, which is useful for identifying cross-annex regulatory status of the same chemical substance.

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Source note for STEVIA REBAUDIANA LEAF/STEM EXTRACT

This page reproduces the CosIng inventory entry for STEVIA REBAUDIANA LEAF/STEM EXTRACT from public European Commission cosmetic ingredient materials and shows linked identifiers even when no direct annex match is currently attached.

Use this inventory page to research STEVIA REBAUDIANA LEAF/STEM EXTRACT and compare linked records, but verify restrictions and legal status against the current official source text and law before making regulatory decisions.

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