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InventoryRef 5781515/10/2010

KAEMPFEROL

3,4',5,7-Tetrahydroxyflavone

KAEMPFEROL is listed in the EU CosIng inventory, but no direct annex records are linked on this page yet.

Regulatory evidence by market

No rule for this ingredient has been imported for any of the 13 markets tracked here.

That describes this inventory, not the law. No imported rule is not evidence that an ingredient is permitted: a rule may exist under another name or identifier, or in a dataset not yet imported here.

Chemical identity and properties

PubChem 2D chemical structure for CAS 520-18-3
CAS 520-18-3PubChem CID 5280863

Kaempferol

Kaempferol is a tetrahydroxyflavone in which the four hydroxy groups are located at positions 3, 5, 7 and 4'. Acting as an antioxidant by reducing oxidative stress, it is currently under consideration as a possible cancer treatment. It has a role as a geroprotector, an antibacterial agent, a plant metabolite, a human xenobiotic metabolite, a human urinary metabolite and a human blood serum metabolite. It is a member of flavonols, a tetrahydroxyflavone and a 7-hydroxyflavonol. It is a conjugate acid of a kaempferol oxoanion. ChEBI

IUPAC name
3,5,7-trihydroxy-2-(4-hydroxyphenyl)chromen-4-one
Molecular formula
C15H10O6
Molecular weight
286.24 g/mol
Exact mass
286.04773803 Da
XLogP3
1.9
Topological polar surface area
107.0 Ų
Hydrogen-bond donors
4
Hydrogen-bond acceptors
6
Covalent units
1
Defined stereocentres
0

Also known as

KaempherolRobigeninRhamnoluteinPopulnetinTrifolitinIndigo YellowPelargidenolonRhamnolutin
16 more reported names
KempferolSwartziol3,4',5,7-TetrahydroxyflavoneNimbecetin3,5,7-Trihydroxy-2-(4-hydroxyphenyl)-4H-chromen-4-oneCampherolKampferolKampherolKaemferol5,7,4'-TrihydroxyflavonolPelargidenolon 14973,5,7-Trihydroxy-2-(4-hydroxyphenyl)-4H-1-benzopyran-4-oneC.I. 756404H-1-Benzopyran-4-one, 3,5,7-trihydroxy-2-(4-hydroxyphenyl)-Flavone, 3,4',5,7-tetrahydroxy-NSC-407289
External database identifiers

Retrieved from NIH PubChem on 2026-08-31 by checksum-valid CAS matching. Chemical properties do not replace the regulatory decision on this page.

Inventory details for KAEMPFEROL

INCI name

KAEMPFEROL

Description

3,4',5,7-Tetrahydroxyflavone

Record provenance

Inventory reference
57815
Imported identity
KAEMPFEROL
Source update
15/10/2010
European Commission CosIng source notes

Key data

Restriction
Function
ANTIOXIDANT
Inhibiting reactions promoted by oxygen, thus avoiding oxidation and rancidity.
SKIN CONDITIONING - EMOLLIENT
Acting as lubricants on the skin surface providing the skin with a soft and smooth appearance.

Official EU ingredient-name evidence

The ingredient name exactly matches the official 2025 EU glossary of common ingredient names.

Ingredients with overlapping formulation functions

Additional official and scientific sources

11 external databases to check this identity in

How KAEMPFEROL appears in the CosIng inventory

The CosIng inventory lists KAEMPFEROL as a cosmetic ingredient and this page links it to 0 annex records. The inventory entry captures names and identifiers, while the annex records show where the substance is prohibited, restricted or positively listed in EU cosmetics law.

KAEMPFEROL is also tagged with 2 cosmetic functions in the official data. Function labels describe intended use, but they do not replace regulatory review of linked annex records before formulation or labelling work.

Frequently asked questions

KAEMPFEROL is listed in the EU CosIng ingredient inventory with no direct annex restriction records linked at this time. Absence of an annex link does not guarantee unrestricted use — always verify against the current official CosIng database before formulating.

According to the EU CosIng inventory, KAEMPFEROL carries the following function designation(s):

CAS 520-18-3 may appear across multiple EU annex records. Viewing the CAS lookup page shows all Annex II–VI entries sharing this identifier, which is useful for identifying cross-annex regulatory status of the same chemical substance.

Use the INCI Checker to screen a full ingredient list across selected markets, or compare this substance across all supported market datasets.

Source note for KAEMPFEROL

This page reproduces the CosIng inventory entry for KAEMPFEROL from public European Commission cosmetic ingredient materials and shows linked identifiers even when no direct annex match is currently attached.

Use this inventory page to research KAEMPFEROL and compare linked records, but verify restrictions and legal status against the current official source text and law before making regulatory decisions.

Tools & next steps

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