What does the restriction note for MEA-SULFITE mean?

The restriction field for MEA-SULFITE reads: III/61. This is the restriction note from the CosIng inventory. For authoritative conditions and limits, always refer to the linked annex entries.

What other records share CAS 13427-63-9?

CAS 13427-63-9 may appear across multiple EU annex records. The CAS lookup page shows all Annex II–VI entries sharing this identifier, useful for identifying cross-annex regulatory status of the same chemical substance.

How do I check if my formula contains MEA-SULFITE?

Use the INCI Checker to screen a full ingredient list across selected markets, or use the substance market comparison to review this identity across all supported market datasets.

InventoryRef 5776315/10/2010

MEA-SULFITE

2-Hydroxyethylammonium Hydrogen Sulphite

MEA-SULFITE is linked to 1 EU annex record on this page. Inventory note: III/61.

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Regulatory evidence by market

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Market	Evidence status	Records	Source language
European Union	Evidence linked Restricted entry found Open this evidence	1	English and EU languages
Great Britain	Source mapped Official source mapped; ingredient rule not imported	0	English
Canada	Source mapped Official source mapped; ingredient rule not imported	0	English and French
New Zealand	Source mapped Official source mapped; ingredient rule not imported	0	English
ASEAN	Source mapped Official source mapped; ingredient rule not imported	0	English and national languages
China	Source mapped Official source mapped; ingredient rule not imported	0	Chinese with selected English material
Japan	Source mapped Official source mapped; ingredient rule not imported	0	Japanese; official English translation available
South Korea	Source mapped Official source mapped; ingredient rule not imported	0	Korean with some English names
United States	Source mapped Official source mapped; ingredient rule not imported	0	English
Australia	Source mapped Official source mapped; ingredient rule not imported	0	English
Brazil	Source mapped Official source mapped; ingredient rule not imported	0	Portuguese with INCI crosswalks
India	Source mapped Official source mapped; ingredient rule not imported	0	English and Hindi
Saudi Arabia	Source mapped Official source mapped; ingredient rule not imported	0	Arabic and English

Chemical identity and properties

PubChem 2D chemical structure for CAS 13427-63-9

CAS 13427-63-9PubChem CID 16204960

Monoethanolamine sulfite

The CIR Expert Panel concluded that ethanolamine and the 12 related ethanolamine salts, listed below, are safe in the present practices of use and concentration described in this safety assessment (rinse-off products only) when formulated to be non-irritating. The Panel cautioned that ingredients should not be used in cosmetic products in which N-nitroso compounds may be formed...MEA-Sulfite... — Cosmetic Ingredient Review (CIR)

IUPAC name: hydrogen sulfite;2-hydroxyethylazanium

Molecular formula: C2H9NO4S
Molecular weight: 143.16 g/mol
Exact mass: 143.02522894 Da
Topological polar surface area: 127.0 Å²
Hydrogen-bond donors: 3
Hydrogen-bond acceptors: 5
Covalent units: 2
Defined stereocentres: 0

Also known as

2-Hydroxyethylammonium hydrogen sulphiteUNII-2Z55RA7FXVEINECS 236-546-32Z55RA7FXVM-ESNRefChem:159569MEA-SULFITE [INCI]2-AMINOETHANOL HYDROSULFITE

9 more reported names

ETHANOL, 2-AMINO-, SULFITE (1:1)ETHANOL, 2-AMINO-, SULFITE (1:1) (SALT)ETHANOLAMINE SULFITE (1:1)MEA-SULFITEMONAMINE BTNMONOETHANOLAMINE BISULFITEMONOETHANOLAMINE SESQUISULFITETHIOSET M2-Hydroxyethan-1-aminium hydrogen sulfite

Open full PubChem record PubChem annotations 3D structure image

External database identifiers

EPA DTXSID:DTXSID2050401

Retrieved from NIH PubChem on 2026-08-31 by checksum-valid CAS matching. Chemical properties do not replace the regulatory decision on this page.

Inventory details for MEA-SULFITE

INCI name

MEA-SULFITE

Description

2-Hydroxyethylammonium Hydrogen Sulphite

Record provenance

Inventory reference: 57763
Imported identity: MEA-SULFITE
Source update: 15/10/2010

European Commission CosIng source notes

Annex records for MEA-SULFITE

Annex III Restriction reference

Entry 61

Monoalkylamines, monoalkanolamines and their salts

Key data

CAS

13427-63-9

236-546-3

Restriction

III/61

Function

HAIR FIXING: Permitting physical control of hair style.

Official EU ingredient-name evidence

The ingredient name exactly matches the official 2025 EU glossary of common ingredient names.

#16092 · MEA-SULFITE

Ingredients with overlapping formulation functions

LACTOSYL CHITOSAN HCLBINDING; FILM FORMING; HAIR FIXING; HUMECTANT; VISCOSITY CONTROLLING

LAURYL ACRYLATE CROSSPOLYMERHAIR FIXING

LAURYL METHACRYLATE/GLYCOL DIMETHACRYLATE CROSSPOLYMERFILM FORMING, HAIR FIXING

LINUM USITATISSIMUM SEED POLYSACCHARIDEHAIR FIXING, HAIR WAVING OR STRAIGHTENING

METHACRYLIC ACID/SODIUM ACRYLAMIDOMETHYL PROPANE SULFONATE COPOLYMERFILM FORMING, HAIR FIXING

METHACRYLOYL ETHYL BETAINE/ACRYLATES COPOLYMERANTISTATIC, FILM FORMING, HAIR FIXING

METHOXY PEG-100/POLYEPSILON CAPROLACTONE ETHYLHEXANOATEBUFFERING, FILM FORMING, HAIR CONDITIONING, HAIR FIXING

METHOXY PEG-100/POLYEPSILON CAPROLACTONE PALMITATEBUFFERING, FILM FORMING, HAIR CONDITIONING, HAIR FIXING

Additional official and scientific sources

11 external databases to check this identity in

Each link searches that source for this identity. What each source is, and its legal weight

ECHA CHEM / Information on chemicals PubChem PUG REST EU Safety Gate cosmetic product alerts ECHA CHEM US EPA CompTox Cosmetic Ingredient Review safety assessments FDA Global Substance Registration System ILO/WHO International Chemical Safety Cards Japan NITE-CHRIP NIOSH Pocket Guide to Chemical Hazards OECD eChemPortal

How MEA-SULFITE appears in the CosIng inventory

The CosIng inventory lists MEA-SULFITE as a cosmetic ingredient and this page links it to 1 annex record. The inventory entry captures names and identifiers, while the annex record shows where the substance is prohibited, restricted or positively listed in EU cosmetics law.

MEA-SULFITE is also tagged with 1 cosmetic function in the official data. Function labels describe intended use, but they do not replace regulatory review of linked annex records before formulation or labelling work.

Frequently asked questions

MEA-SULFITE appears in the EU CosIng inventory and has linked annex records. Check the annex records above for applicable restrictions, concentration limits and conditions of use. Annex II listing means prohibited; Annex III means restricted; Annexes IV, V and VI mean permitted under specified conditions.

The restriction field for MEA-SULFITE reads: "III/61". This is the restriction note recorded in the CosIng inventory for this ingredient. For authoritative conditions and limits, always refer to the linked annex entries above.

According to the EU CosIng inventory, MEA-SULFITE carries the following function designation(s):

HAIR FIXING

CAS 13427-63-9 may appear across multiple EU annex records. Viewing the CAS lookup page shows all Annex II–VI entries sharing this identifier, which is useful for identifying cross-annex regulatory status of the same chemical substance.

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Source note for MEA-SULFITE

This page combines the CosIng inventory entry for MEA-SULFITE with 1 linked Annex II–VI record from the local dataset built from public European Commission cosmetic ingredient materials.

Use this inventory page to research MEA-SULFITE and compare linked records, but verify restrictions and legal status against the current official source text and law before making regulatory decisions.

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Tools & next steps

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