Is OCTENIDINE HCL safe to use in EU cosmetics?

OCTENIDINE HCL is listed in the EU CosIng ingredient inventory with no direct annex restriction records linked at this time. Always verify against the current official CosIng database before formulating.

What other records share CAS 70775-75-6?

CAS 70775-75-6 may appear across multiple EU annex records. The CAS lookup page shows all Annex II–VI entries sharing this identifier, useful for identifying cross-annex regulatory status of the same chemical substance.

How do I check if my formula contains OCTENIDINE HCL?

Use the INCI Checker to screen a full ingredient list across selected markets, or use the substance market comparison to review this identity across all supported market datasets.

InventoryRef 5755915/10/2010

OCTENIDINE HCL

1-Octanamine, N,N'-(1,10-decanediyldi-1(4H)-pyridinyl-4-ylidene)bis-, dihydrochloride

OCTENIDINE HCL is listed in the EU CosIng inventory, but no direct annex records are linked on this page yet.

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Regulatory evidence by market

No rule for this ingredient has been imported for any of the 13 markets tracked here.

That describes this inventory, not the law. No imported rule is not evidence that an ingredient is permitted: a rule may exist under another name or identifier, or in a dataset not yet imported here.

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Chemical identity and properties

PubChem 2D chemical structure for CAS 70775-75-6

CAS 70775-75-6PubChem CID 51166

Octenidine Hydrochloride

IUPAC name: N-octyl-1-[10-(4-octylimino-1-pyridinyl)decyl]pyridin-4-imine;dihydrochloride

Molecular formula: C36H64Cl2N4
Molecular weight: 623.8 g/mol
Exact mass: 622.4508034 Da
Topological polar surface area: 31.2 Å²
Hydrogen-bond donors: 2
Hydrogen-bond acceptors: 4
Covalent units: 3
Defined stereocentres: 0

Also known as

Octenidine HClSensidin doWin 41464-2LAS-189962WIN-41464-2octenidermOctenidolRefChem:856047

16 more reported names

N,N'-(1,10-decanediyldi-1-(4H)-pyridinyl-4-ylidene)bis-(1-octamine) dihydrochloride274-861-8Octenidine dihydrochlorideOctenidine (dihydrochloride)1-Octanamine,N,N'-(1,10-decanediyldi-1(4H)-pyridinyl-4-ylidene)bis-, hydrochloride (1:2)Octenidine hydrochloride [USAN]1,1'-(Decane-1,10-diyl)bis(N-octylpyridin-4(1H)-imine) dihydrochlorideN-octyl-1-[10-(4-octyliminopyridin-1-yl)decyl]pyridin-4-imine;dihydrochlorideCS-6224O03881,1'-Decamethylenebis(1,4-dihydro-4-(octylimino)pyridine) dihydrochlorideN,N'-(1,10-Decanediyldi-1(4H)-pyridinyl-4-ylidene)bis(1-octanamine) dihydrochlorideN,N'-(1,1'-(Decane-1,10-diyl)bis(pyridin-1(1H)-yl-4(1H)-ylidene))bis(octan-1-amine) dihydrochlorideOctenidine hydrochloride (USAN)N,N'-(Decane-1,10-diyldi-1(4H)-pyridyl-4-ylidene)bis(octylammonium) dichloride1-Octanamine, N,N'-(1,10-decanediyldi-1(4H)-pyridinyl-4-ylidene)bis-, dihydrochloride

Open full PubChem record PubChem annotations 3D structure image

External database identifiers

ChEMBL:CHEMBL36342

Retrieved from NIH PubChem on 2026-08-31 by checksum-valid CAS matching. Chemical properties do not replace the regulatory decision on this page.

Inventory details for OCTENIDINE HCL

INCI name

OCTENIDINE HCL

Description

1-Octanamine, N,N'-(1,10-decanediyldi-1(4H)-pyridinyl-4-ylidene)bis-, dihydrochloride

Record provenance

Inventory reference: 57559
Imported identity: OCTENIDINE HCL
Source update: 15/10/2010

European Commission CosIng source notes

Annex records for OCTENIDINE HCL

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Key data

CAS

70775-75-6

274-861-8

Restriction

—

Function

ANTIMICROBIAL: Preventing and/or slowing down microbial growth.

Official EU ingredient-name evidence

The ingredient name exactly matches the official 2025 EU glossary of common ingredient names.

#17796 · OCTENIDINE HCl

Ingredients with overlapping formulation functions

NORLEUCYL S-FROG OCTAPEPTIDE-1 D-LEUCYL D-LYSYL TRIPEPTIDE-90 AMIDEANTIMICROBIAL; ANTI-SEBUM

NYMPHAEA TETRAGONA PHYTOPLACENTA EXTRACTANTIMICROBIAL, HAIR CONDITIONING, HUMECTANT, SKIN CONDITIONING

O-CRESOLANTIMICROBIAL, PERFUMING

O-CYMEN-5-OLANTIMICROBIAL, DEODORANT, PRESERVATIVE

OCTYLISOTHIAZOLINONEANTIMICROBIAL

OENANTHE JAVANICA EXTRACTANTIMICROBIAL

OENOTHERA LACINIATA LEAF/STEM EXTRACTANTIMICROBIAL, SKIN PROTECTING

OLEOCANTHALANTIMICROBIAL, ANTIOXIDANT, ORAL CARE, SKIN PROTECTING

Additional official and scientific sources

11 external databases to check this identity in

Each link searches that source for this identity. What each source is, and its legal weight

ECHA CHEM / Information on chemicals PubChem PUG REST EU Safety Gate cosmetic product alerts ECHA CHEM US EPA CompTox Cosmetic Ingredient Review safety assessments FDA Global Substance Registration System ILO/WHO International Chemical Safety Cards Japan NITE-CHRIP NIOSH Pocket Guide to Chemical Hazards OECD eChemPortal

How OCTENIDINE HCL appears in the CosIng inventory

The CosIng inventory lists OCTENIDINE HCL as a cosmetic ingredient and this page links it to 0 annex records. The inventory entry captures names and identifiers, while the annex records show where the substance is prohibited, restricted or positively listed in EU cosmetics law.

OCTENIDINE HCL is also tagged with 1 cosmetic function in the official data. Function labels describe intended use, but they do not replace regulatory review of linked annex records before formulation or labelling work.

Frequently asked questions

OCTENIDINE HCL is listed in the EU CosIng ingredient inventory with no direct annex restriction records linked at this time. Absence of an annex link does not guarantee unrestricted use — always verify against the current official CosIng database before formulating.

According to the EU CosIng inventory, OCTENIDINE HCL carries the following function designation(s):

ANTIMICROBIAL

CAS 70775-75-6 may appear across multiple EU annex records. Viewing the CAS lookup page shows all Annex II–VI entries sharing this identifier, which is useful for identifying cross-annex regulatory status of the same chemical substance.

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Source note for OCTENIDINE HCL

This page reproduces the CosIng inventory entry for OCTENIDINE HCL from public European Commission cosmetic ingredient materials and shows linked identifiers even when no direct annex match is currently attached.

Use this inventory page to research OCTENIDINE HCL and compare linked records, but verify restrictions and legal status against the current official source text and law before making regulatory decisions.

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Tools & next steps

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