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InventoryRef 5636315/10/2010

HESPERIDIN METHYL CHALCONE

2-Propen-1-one,1-[4-[[6-O-(6-deoxy-alfa-L-mannopyranosyl)-beta-D-glucopyranosyl]oxy]-2-hydroxy-6-methoxyphenyl]-3-(3-hydroxy-4-methoxyphenyl)-, (E)-

HESPERIDIN METHYL CHALCONE is listed in the EU CosIng inventory, but no direct annex records are linked on this page yet.

Regulatory evidence by market

No rule for this ingredient has been imported for any of the 13 markets tracked here.

That describes this inventory, not the law. No imported rule is not evidence that an ingredient is permitted: a rule may exist under another name or identifier, or in a dataset not yet imported here.

Chemical identity and properties

PubChem 2D chemical structure for CAS 24292-52-2
CAS 24292-52-2PubChem CID 6436550

Hesperidin methylchalcone

hesperidin methylchalcone has been reported in Myrtus communis with data available. LOTUS - the natural products occurrence database

IUPAC name
(E)-3-(3-hydroxy-4-methoxyphenyl)-1-[2-hydroxy-6-methoxy-4-[(2S,3R,4S,5S,6R)-3,4,5-trihydroxy-6-[[(2R,3R,4R,5R,6S)-3,4,5-trihydroxy-6-methyloxan-2-yl]oxymethyl]oxan-2-yl]oxyphenyl]prop-2-en-1-one
Molecular formula
C29H36O15
Molecular weight
624.6 g/mol
Exact mass
624.20542044 Da
XLogP3
-0.3
Topological polar surface area
234.0 Ų
Hydrogen-bond donors
8
Hydrogen-bond acceptors
15
Covalent units
1
Defined stereocentres
10

Also known as

Hesperidin methyl chalcone4T2GVA922Xhesperidine methylchalcone(E)-1-(4-((6-O-(6-Deoxy-alpha-L-mannopyranosyl)-beta-D-glucopyranosyl)oxy)-2-hydroxy-6-methoxyphenyl)-3-(3-hydroxy-4-methoxyphenyl)-2-propen-1-one2-Propen-1-one, 1-(4-((6-O-(6-deoxy-alpha-L-mannopyranosyl)-beta-D-glucopyranosyl)oxy)-2-hydroxy-6-methoxyphenyl)-3-(3-hydroxy-4-methoxyphenyl)-, (2E)-RefChem:145828246-128-2EYELISS
16 more reported names
Hesperidine Methyl Chalcone(2E)-1-[4-[[6-O-(6-Deoxy-alpha-L-mannopyranosyl)-beta-D-glucopyranosyl]oxy]-2-hydroxy-6-methoxyphenyl]-3-(3-hydroxy-4-methoxyphenyl)-2-propen-1-oneEINECS 246-128-2UNII-4T2GVA922XFDHNLHLOJLLXDH-JIYHLSBYSA-N3,4',6'-Trihydroxy-4,2'-dimethoxychalcone 4'-O-rutinoside(E)-3-(3-Hydroxy-4-methoxyphenyl)1-(4-((6-O-(6-Deoxy-alpha-L-mannopyranosyl)-beta-D-glucopyranosyl)oxy)-2-hydroxy-6-methoxyphenyl)-3-(3-hydroxy-4-methoxyphenyl)prop-2-en-1-one2-Propen-1-one, 1-[4-[[6-O-(6-deoxy-.alpha.-L-mannopyranosyl)-.beta.-D-glucopyranosyl]oxy]-2-hydroxy-6-methoxyphenyl]-3-(3-hydroxy-4-methoxyphenyl)-, (2E)-Chalcone, 2',3,4'-trihydroxy-4,6'-dimethoxy-, 4'-(6-O-(6-deoxy-alpha-L-mannopyranosyl)-beta-D-glucopyranoside)HESPERIDIN METHYL CHALCONE [VANDF]MS-30814HESPERIDIN METHYL CHALCONE [WHO-DD]HY-126382CS-0103227T7980
External database identifiers

Retrieved from NIH PubChem on 2026-08-31 by checksum-valid CAS matching. Chemical properties do not replace the regulatory decision on this page.

Inventory details for HESPERIDIN METHYL CHALCONE

INCI name

HESPERIDIN METHYL CHALCONE

Description

2-Propen-1-one,1-[4-[[6-O-(6-deoxy-alfa-L-mannopyranosyl)-beta-D-glucopyranosyl]oxy]-2-hydroxy-6-methoxyphenyl]-3-(3-hydroxy-4-methoxyphenyl)-, (E)-

Record provenance

Inventory reference
56363
Imported identity
HESPERIDIN METHYL CHALCONE
Source update
15/10/2010
European Commission CosIng source notes

Key data

Restriction
Function
ANTIOXIDANT
Inhibiting reactions promoted by oxygen, thus avoiding oxidation and rancidity.

Official EU ingredient-name evidence

The ingredient name exactly matches the official 2025 EU glossary of common ingredient names.

Ingredients with overlapping formulation functions

Additional official and scientific sources

11 external databases to check this identity in

How HESPERIDIN METHYL CHALCONE appears in the CosIng inventory

The CosIng inventory lists HESPERIDIN METHYL CHALCONE as a cosmetic ingredient and this page links it to 0 annex records. The inventory entry captures names and identifiers, while the annex records show where the substance is prohibited, restricted or positively listed in EU cosmetics law.

HESPERIDIN METHYL CHALCONE is also tagged with 1 cosmetic function in the official data. Function labels describe intended use, but they do not replace regulatory review of linked annex records before formulation or labelling work.

Frequently asked questions

HESPERIDIN METHYL CHALCONE is listed in the EU CosIng ingredient inventory with no direct annex restriction records linked at this time. Absence of an annex link does not guarantee unrestricted use — always verify against the current official CosIng database before formulating.

According to the EU CosIng inventory, HESPERIDIN METHYL CHALCONE carries the following function designation(s):

CAS 24292-52-2 may appear across multiple EU annex records. Viewing the CAS lookup page shows all Annex II–VI entries sharing this identifier, which is useful for identifying cross-annex regulatory status of the same chemical substance.

Use the INCI Checker to screen a full ingredient list across selected markets, or compare this substance across all supported market datasets.

Source note for HESPERIDIN METHYL CHALCONE

This page reproduces the CosIng inventory entry for HESPERIDIN METHYL CHALCONE from public European Commission cosmetic ingredient materials and shows linked identifiers even when no direct annex match is currently attached.

Use this inventory page to research HESPERIDIN METHYL CHALCONE and compare linked records, but verify restrictions and legal status against the current official source text and law before making regulatory decisions.

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