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CAS 695-06-7 may appear across multiple EU annex records. The CAS lookup page shows all Annex II–VI entries sharing this identifier, useful for identifying cross-annex regulatory status of the same chemical substance.

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InventoryRef 5631015/10/2010

GAMMA-CAPROLACTONE

Hexan-4-olide

GAMMA-CAPROLACTONE is listed in the EU CosIng inventory, but no direct annex records are linked on this page yet.

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Regulatory evidence by market

No rule for this ingredient has been imported for any of the 13 markets tracked here.

That describes this inventory, not the law. No imported rule is not evidence that an ingredient is permitted: a rule may exist under another name or identifier, or in a dataset not yet imported here.

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Chemical identity and properties

PubChem 2D chemical structure for CAS 695-06-7

CAS 695-06-7PubChem CID 12756

gamma-Hexalactone

Gamma-caprolactone is a gamma-lactone that is oxolan-2-one substituted by an ethyl group at position 5. It has a role as a human blood serum metabolite. — ChEBI

IUPAC name: 5-ethyloxolan-2-one

Molecular formula: C6H10O2
Molecular weight: 114.14 g/mol
Exact mass: 114.068079557 Da
XLogP3: 0.7
Topological polar surface area: 26.3 Å²
Hydrogen-bond donors: 0
Hydrogen-bond acceptors: 2
Covalent units: 1
Defined stereocentres: 0

Also known as

gamma-Caprolactone4-Hexanolidegamma-Hexanolactone6-CaprolactoneTonkalideToukalide2(3H)-Furanone, 5-ethyldihydro-Hexanolide-1,4

16 more reported names

Hexan-4-olide4-Ethyl-4-butanolidegamma-Ethylbutyrolactone5-Ethyltetrahydro-2-furanone5-ETHYLDIHYDRO-2(3H)-FURANONEgamma-Ethyl-n-butyrolactoneFEMA No. 2556J16NAT1G41NSC-24255NSC-134769CHEBI:85235RefChem:523587CHEBI:37581211-778-8gamma-Lactone5-Ethyldihydrofuran-2(3H)-one

Open full PubChem record PubChem annotations 3D structure image

External database identifiers

ChEBI:CHEBI:85235
ChEMBL:CHEMBL192458
EPA DTXSID:DTXSID8041298
PubMed:22085026
PubMed:21288487
PubMed:20415420
PubMed:19954143
PubMed:17504488
PubMed:15580663
PubMed:15186115
PubMed:12166975
PubMed:11429859

Retrieved from NIH PubChem on 2026-08-31 by checksum-valid CAS matching. Chemical properties do not replace the regulatory decision on this page.

Inventory details for GAMMA-CAPROLACTONE

INCI name

GAMMA-CAPROLACTONE

Description

Hexan-4-olide

Record provenance

Inventory reference: 56310
Imported identity: GAMMA-CAPROLACTONE
Source update: 15/10/2010

European Commission CosIng source notes

Annex records for GAMMA-CAPROLACTONE

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Key data

CAS

695-06-7

211-778-8

Restriction

—

Function

FRAGRANCE: Imparting an odour or taste. Creating a perceivable pleasant smell and/or masking a bad smell.
PERFUMING: Used for perfume and aromatic raw materials.

Official EU ingredient-name evidence

The ingredient name exactly matches the official 2025 EU glossary of common ingredient names.

#10767 · GAMMA-CAPROLACTONE

Ingredients with overlapping formulation functions

FRAGARIA ANANASSA FRUIT WATERFRAGRANCE, PERFUMING

FRAGARIA ANANASSA FRUIT WATER EXTRACTSKIN CONDITIONING - EMOLLIENT; FRAGRANCE; PERFUMING

FURFURALFRAGRANCE, SOLVENT

FUSANUS SPICATUS WOOD OILFRAGRANCE

GAMMA-NONALACTONEFRAGRANCE, PERFUMING, SKIN CONDITIONING

GARCINIA HUMILIS PEEL EXTRACTFRAGRANCE, HAIR CONDITIONING, SKIN CONDITIONING

GAULTHERIA FRAGRANTISSIMA LEAF OILFRAGRANCE

GAULTHERIA PROCUMBENS FLOWER/LEAF/STEM OILFRAGRANCE, SKIN CONDITIONING

Additional official and scientific sources

11 external databases to check this identity in

Each link searches that source for this identity. What each source is, and its legal weight

ECHA CHEM / Information on chemicals PubChem PUG REST EU Safety Gate cosmetic product alerts ECHA CHEM US EPA CompTox Cosmetic Ingredient Review safety assessments FDA Global Substance Registration System ILO/WHO International Chemical Safety Cards Japan NITE-CHRIP NIOSH Pocket Guide to Chemical Hazards OECD eChemPortal

How GAMMA-CAPROLACTONE appears in the CosIng inventory

The CosIng inventory lists GAMMA-CAPROLACTONE as a cosmetic ingredient and this page links it to 0 annex records. The inventory entry captures names and identifiers, while the annex records show where the substance is prohibited, restricted or positively listed in EU cosmetics law.

GAMMA-CAPROLACTONE is also tagged with 2 cosmetic functions in the official data. Function labels describe intended use, but they do not replace regulatory review of linked annex records before formulation or labelling work.

Frequently asked questions

GAMMA-CAPROLACTONE is listed in the EU CosIng ingredient inventory with no direct annex restriction records linked at this time. Absence of an annex link does not guarantee unrestricted use — always verify against the current official CosIng database before formulating.

According to the EU CosIng inventory, GAMMA-CAPROLACTONE carries the following function designation(s):

CAS 695-06-7 may appear across multiple EU annex records. Viewing the CAS lookup page shows all Annex II–VI entries sharing this identifier, which is useful for identifying cross-annex regulatory status of the same chemical substance.

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Source note for GAMMA-CAPROLACTONE

This page reproduces the CosIng inventory entry for GAMMA-CAPROLACTONE from public European Commission cosmetic ingredient materials and shows linked identifiers even when no direct annex match is currently attached.

Use this inventory page to research GAMMA-CAPROLACTONE and compare linked records, but verify restrictions and legal status against the current official source text and law before making regulatory decisions.

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