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InventoryRef 5583715/10/2010

DIETHOXYDIGLYCOL

Diethylene Glycol Diethyl Ether

DIETHOXYDIGLYCOL is listed in the EU CosIng inventory, but no direct annex records are linked on this page yet.

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Regulatory evidence by market

No rule for this ingredient has been imported for any of the 13 markets tracked here.

That describes this inventory, not the law. No imported rule is not evidence that an ingredient is permitted: a rule may exist under another name or identifier, or in a dataset not yet imported here.

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Chemical identity and properties

PubChem 2D chemical structure for CAS 112-36-7
CAS 112-36-7PubChem CID 8179

Diethylene glycol diethyl ether

Diethylene glycol diethyl ether is a clear colorless viscous liquid. (NTP, 1992) — CAMEO Chemicals

IUPAC name
1-ethoxy-2-(2-ethoxyethoxy)ethane
Molecular formula
C8H18O3
Molecular weight
162.23 g/mol
Exact mass
162.125594432 Da
XLogP3
0.4
Topological polar surface area
27.7 Ų
Hydrogen-bond donors
0
Hydrogen-bond acceptors
3
Covalent units
1
Defined stereocentres
0

Also known as

2-Ethoxyethyl etherDiethyl carbitolBis(2-ethoxyethyl) etherDEGDEEEthane, 1,1'-oxybis[2-ethoxy-HSDB 68Ethane, 1,1'-oxybis(2-ethoxy-Glycol, diethylene-, diethyl ether
16 more reported names
EINECS 203-963-7UNII-ZH086O935Zdiethoxydiglycoldiethyleneglycol diethyl etherBRN 1699259HISOLVE EDEAI3-19428ZH086O935Z1,1'-oxybis(2-ethoxy)ethaneCHEBI:44664EC 203-963-74-01-00-02394 (Beilstein Handbook Reference)DIETHYLENE GLYCOL DIETHYL ETHER [MI]DIETHYLENE GLYCOL DIETHYL ETHER [HSDB]bis(2-ethoxyethyl)ether3,6,9Trioxaundecane
Open full PubChem recordPubChem annotations3D structure image
External database identifiers

Evidence from additional scientific databases

NIH PubChem PUG-View
Exact identifier match8179

Attributed physical-property, hazard, environmental and use annotations.

  • First Aid: EYES: First check the victim for contact lenses and remove if present. Flush victim's eyes with water or normal saline solution for 20 to 30 minutes while simultaneously calling a hospital or poison control center. Do not put any ointments, oils, or medication in the victim's eyes without specific instructions from a physician. IMMEDIATELY transport the victim after flushing eyes to a hospital even if no symptoms (such as redness or irritation) develop.; SKIN: IMMEDIATELY flood affected skin with water while removing and isolating all contaminated clothing. Gently wash all affected skin areas thoroughly with soap and water. If symptoms such as redness or irritation develop, IMMEDIATELY call a physician and be prepared to transport the victim to a hospital for treatment.; INHALATION: IMMEDIATELY leave the contaminated area; take deep breaths of fresh air. If symptoms (such as wheezing, coughing, shortness of breath, or burning in the mouth, throat, or chest) develop, call a physician and be prepared to transport the victim to a hospital. Provide proper respiratory protection to rescuers entering an unknown atmosphere. Whenever possible, Self-Contained Breathing Apparatus (SCBA) shou Source: CAMEO Chemicals
  • Note: This chemical does not meet GHS hazard criteria for 5.6% (21 of 374) of reports. Source: European Chemicals Agency (ECHA)
  • Signal: Warning Source: European Chemicals Agency (ECHA)
  • GHS Hazard Statements: H315 (42.8%): Causes skin irritation [Warning Skin corrosion/irritation]; H319 (51.3%): Causes serious eye irritation [Warning Serious eye damage/eye irritation] Source: European Chemicals Agency (ECHA)
  • Precautionary Statement Codes: P264, P264+P265, P280, P302+P352, P305+P351+P338, P321, P332+P317, P337+P317, and P362+P364 (click each P-code to see the statement) Source: European Chemicals Agency (ECHA)
  • ECHA C&L Notifications Summary: Aggregated GHS information provided per 374 reports by companies from 7 notifications to the ECHA C&L Inventory. Each notification may be associated with multiple companies.; Reported as not meeting GHS hazard criteria per 21 of 374 reports by companies.; There are 4 notifications provided by 353 of 374 reports by companies with hazard statement code(s).; Information may vary between notifications depending on impurities, additives, and other factors. The percentage value in parenthesis indicates the notified classification ratio from companies that provide hazard codes. Only hazard codes with percentage values above 10% are shown. For more detailed information, please visit ECHA C&L website. Source: European Chemicals Agency (ECHA)
  • Signal: Warning Source: NITE-CMC
  • GHS Hazard Statements: H227: Combustible liquid [Warning Flammable liquids]; H319: Causes serious eye irritation [Warning Serious eye damage/eye irritation] Source: NITE-CMC
  • Precautionary Statement Codes: P210, P264+P265, P280, P305+P351+P338, P337+P317, P370+P378, P403, and P501 (click each P-code to see the statement) Source: NITE-CMC
  • NFPA Health Rating: 1 - Materials that, under emergency conditions, can cause significant irritation. Source: Hazardous Substances Data Bank (HSDB)
  • NFPA Fire Rating: 2 - Materials that must be moderately heated or exposed to relatively high ambient temperatures before ignition can occur. Materials would not under normal conditions form hazardous atmospheres with air, but under high ambient temperatures or under moderate heating could release vapor in sufficient quantities to produce hazardous atmospheres with air. Source: Hazardous Substances Data Bank (HSDB)
  • NFPA Instability Rating: 1 - Materials that in themselves are normally stable but that can become unstable at elevated temperatures and pressures. Source: Hazardous Substances Data Bank (HSDB)
  • Environmental Bioconcentration: An estimated BCF of 3 was calculated in fish for diethylene glycol diethyl ether(SRC), using a log Kow of 0.39(1) and a regression-derived equation(2). According to a classification scheme(3), this BCF suggests the potential for bioconcentration in aquatic organisms is low(SRC). Source: Hazardous Substances Data Bank (HSDB)
  • Environmental Fate: TERRESTRIAL FATE: Based on a classification scheme(1), an estimated Koc value of 39(SRC), determined from a log Kow of 0.39(2) and a regression-derived equation(3), indicates that diethylene glycol diethyl ether is expected to have very high mobility in soil(SRC). Volatilization of diethylene glycol diethyl ether from moist soil surfaces is not expected to be an important fate process(SRC) given an estimated Henry's Law constant of 1.1X10-7 atm-cu m/mole(SRC), derived from Its vapor pressure, 0.52 mm Hg(4), and water solubility, 1X10+6 mg/L(5). Diethylene glycol diethyl ether may volatilize from dry soil surfaces(SRC) based upon its vapor pressure(4). Biodegradation of diethylene glycol diethyl ether is not expected to be an important fate process in soil based on biodegradation studies conducted with sewage seed(6-7). Source: Hazardous Substances Data Bank (HSDB)
  • Environmental Fate: AQUATIC FATE: Based on a classification scheme(1), an estimated Koc value of 39(SRC), determined from a log Kow of 0.39(2) and a regression-derived equation(3), indicates that diethylene glycol diethyl ether is not expected to adsorb to suspended solids and sediment(SRC). Volatilization from water surfaces is not expected(3) based upon an estimated Henry's Law constant of 1.1X10-7 atm-cu m/mole(SRC), derived from its vapor pressure, 0.52 mm Hg(4), and water solubility, 1X10+6 mg/L(5). According to a classification scheme(6), an estimated BCF of 3(SRC), from its log Kow(2) and a regression-derived equation(7), suggests the potential for bioconcentration in aquatic organisms is low(SRC). Biodegradation of diethylene glycol diethyl ether is not expected to be an important fate process in water based on biodegradation studies conducted with sewage seed(8-9). Source: Hazardous Substances Data Bank (HSDB)
  • Environmental Fate: ATMOSPHERIC FATE: According to a model of gas/particle partitioning of semivolatile organic compounds in the atmosphere(1), diethylene glycol diethyl ether, which has a vapor pressure of 0.52 mm Hg at 25 °C(2), is expected to exist solely as a vapor in the ambient atmosphere. Vapor-phase diethylene glycol diethyl ether is degraded in the atmosphere by reaction with photochemically-produced hydroxyl radicals(SRC); the half-life for this reaction in air is estimated to be 14 hours(SRC), calculated from its rate constant of 2.7X10-11 cu cm/molecule-sec at 25 °C(3). Source: Hazardous Substances Data Bank (HSDB)

Mapped by: Existing checksum-valid CAS to unique PubChem CID match. Retrieved: 2026-08-31. Open source record

Scientific classifications and hazard annotations provide context and do not replace the market-specific regulatory decision shown above.

Additional source coverage and match status
SourceResultChecked
NIH PubChem PUG-ViewExact match2026-08-31

A recorded no-match is useful evidence that the source was checked; it is not a claim that the substance does not exist elsewhere.

Retrieved from NIH PubChem on 2026-08-31 by checksum-valid CAS matching. Chemical properties do not replace the regulatory decision on this page.

Inventory details for DIETHOXYDIGLYCOL

INCI name

DIETHOXYDIGLYCOL

Description

Diethylene Glycol Diethyl Ether

Record provenance

Inventory reference
55837
Imported identity
DIETHOXYDIGLYCOL
Source update
15/10/2010
European Commission CosIng source notes
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Key data

CAS
112-36-7
EC
203-963-7
Restriction
—
Function
SOLVENT
Dissolving other components of cosmetics. Solvents are usually liquids (aqueous and nonaqueous).

Official EU ingredient-name evidence

The ingredient name exactly matches the official 2025 EU glossary of common ingredient names.

#8555 · DIETHOXYDIGLYCOL

Ingredients with overlapping formulation functions

DICAPRYLYL ETHERSKIN CONDITIONING, SKIN CONDITIONING - EMOLLIENT, SOLVENT
DICAPRYLYL MALEATESKIN CONDITIONING, SKIN CONDITIONING - EMOLLIENT, SOLVENT
DICAPRYLYL/CAPRYL SEBACATEPLASTICISER, SKIN CONDITIONING - EMOLLIENT, SOLVENT
DICHLOROMETHANEPERFUMING, SOLVENT
DIETHOXYETHYL SUCCINATESOLVENT
DIETHYL OXALATECHELATING, FRAGRANCE, HAIR CONDITIONING, PLASTICISER, SOLVENT
DIETHYL PHTHALATEDENATURANT, FILM FORMING, FRAGRANCE, HAIR CONDITIONING, PLASTICISER, SOLVENT
DIETHYL SEBACATEFRAGRANCE, PLASTICISER, SKIN CONDITIONING, SKIN CONDITIONING - EMOLLIENT, SOLVENT

Additional official and scientific sources

11 external databases to check this identity in

Each link searches that source for this identity. What each source is, and its legal weight

ECHA CHEM / Information on chemicalsPubChem PUG RESTEU Safety Gate cosmetic product alertsECHA CHEMUS EPA CompToxCosmetic Ingredient Review safety assessmentsFDA Global Substance Registration SystemILO/WHO International Chemical Safety CardsJapan NITE-CHRIPNIOSH Pocket Guide to Chemical HazardsOECD eChemPortal

How DIETHOXYDIGLYCOL appears in the CosIng inventory

The CosIng inventory lists DIETHOXYDIGLYCOL as a cosmetic ingredient and this page links it to 0 annex records. The inventory entry captures names and identifiers, while the annex records show where the substance is prohibited, restricted or positively listed in EU cosmetics law.

DIETHOXYDIGLYCOL is also tagged with 1 cosmetic function in the official data. Function labels describe intended use, but they do not replace regulatory review of linked annex records before formulation or labelling work.

Frequently asked questions

DIETHOXYDIGLYCOL is listed in the EU CosIng ingredient inventory with no direct annex restriction records linked at this time. Absence of an annex link does not guarantee unrestricted use — always verify against the current official CosIng database before formulating.

According to the EU CosIng inventory, DIETHOXYDIGLYCOL carries the following function designation(s):

CAS 112-36-7 may appear across multiple EU annex records. Viewing the CAS lookup page shows all Annex II–VI entries sharing this identifier, which is useful for identifying cross-annex regulatory status of the same chemical substance.
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Source note for DIETHOXYDIGLYCOL

This page reproduces the CosIng inventory entry for DIETHOXYDIGLYCOL from public European Commission cosmetic ingredient materials and shows linked identifiers even when no direct annex match is currently attached.

Use this inventory page to research DIETHOXYDIGLYCOL and compare linked records, but verify restrictions and legal status against the current official source text and law before making regulatory decisions.

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