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InventoryRef 5554615/10/2010

CYCLOHEPTASILOXANE

Tetradecamethylcycloheptasiloxane

CYCLOHEPTASILOXANE is listed in the EU CosIng inventory, but no direct annex records are linked on this page yet.

Regulatory evidence by market

No rule for this ingredient has been imported for any of the 13 markets tracked here.

That describes this inventory, not the law. No imported rule is not evidence that an ingredient is permitted: a rule may exist under another name or identifier, or in a dataset not yet imported here.

Chemical identity and properties

PubChem 2D chemical structure for CAS 107-50-6
CAS 107-50-6PubChem CID 7874

Tetradecamethylcycloheptasiloxane

Tetradecamethylcycloheptasiloxane is a macrocyclic organosiloxane composed from seven units of dimethylsiloxane. It has a role as a marine xenobiotic metabolite. It is an organosiloxane and a macrocycle. ChEBI

IUPAC name
2,2,4,4,6,6,8,8,10,10,12,12,14,14-tetradecamethyl-1,3,5,7,9,11,13-heptaoxa-2,4,6,8,10,12,14-heptasilacyclotetradecane
Molecular formula
C14H42O7Si7
Molecular weight
519.07 g/mol
Exact mass
518.13153942 Da
Topological polar surface area
64.6 Ų
Hydrogen-bond donors
0
Hydrogen-bond acceptors
7
Covalent units
1
Defined stereocentres
0

Also known as

Cyclomethicone 7Cycloheptasiloxane, tetradecamethyl-UNII-KCK5L8VU47KCK5L8VU47TetradecamethylcyclotetradecaneheptasiloxaneEINECS 203-496-9J182.220ICHEBI:87988
16 more reported names
2,2,4,4,6,6,8,8,10,10,12,12,14,14-TETRADECAMETHYLCYCLOTETRADECANEHEPTASILOXANECYCLOHEPTASILOXANE, 2,2,4,4,6,6,8,8,10,10,12,12,14,14-TETRADECAMETHYL-RefChem:188486GSANOGQCVHBHIF-UHFFFAOYSA-Ntetradecamethyl cycloheptasiloxaneCycloheptasiloxane,2,2,4,4,6,6,8,8,10,10,12,12,14,14-tetradecamethyl-2,2,4,4,6,6,8,8,10,10,12,12,14,14-TetradecamethylcycloheptasiloxaneC14H42O7Si7Tetradecamethyl-cycloheptasiloxane; 2,2,4,4,6,6,8,8,10,10,12,12,14,14-Tetradecamethyl-cycloheptasiloxaneSimethicone Impurity 17AS-91007Tetradecamethylcycloheptasiloxane in AcetoneSimethicone Impurity 17; TetradecamethylcycloheptasiloxaneTetradecamethyl cycloheptasiloxane Solution in Methanol, 1000ug/mL2,2,4,4,6,6,8,8,10,10,12,12,14,14-Tetradecamethylcycloheptasiloxane #D-7
External database identifiers

Evidence from additional scientific databases

EMBL-EBI ChEBI
Exact identifier matchCHEBI:87988

tetradecamethylcycloheptasiloxane

A macrocyclic organosiloxane composed from seven units of dimethylsiloxane.

Formula
C14H42O7Si7
Average mass
519.085 g/mol
Monoisotopic mass
518.13154 Da
Formal charge
0
  • organosiloxane — is a (CHEBI:48150)
  • macrocycle — is a (CHEBI:51026)
  • marine xenobiotic metabolite — has role (CHEBI:83399)
  • marine xenobiotic metabolite — has role (CHEBI:83399)
  • organosiloxane — is a (CHEBI:48150)
  • macrocycle — is a (CHEBI:51026)
Additional curated names
tetradecamethylcycloheptasiloxaneCyclomethicone 7
Cross-references from this source
  • CAS: 107-50-6 — NIST Chemistry WebBook
  • CAS: 107-50-6 — ChemIDplus
  • REGISTRY_NUMBER: 1717235 — Reaxys

Mapped by: Exact CAS cross-reference in the ChEBI compound record. Source updated: 2016-04-07. Retrieved: 2026-08-31. Open source record

NIH PubChem PUG-View
Exact identifier match7874

Attributed physical-property, hazard, environmental and use annotations.

  • Note: This chemical does not meet GHS hazard criteria for 98% (50 of 51) of all reports. Source: European Chemicals Agency (ECHA)
  • GHS Hazard Statements: Not Classified; Reported as not meeting GHS hazard criteria by 50 of 51 companies (only 2% companies provided GHS information). For more detailed information, please visit ECHA C&L website. Source: European Chemicals Agency (ECHA)
  • ECHA C&L Notifications Summary: Aggregated GHS information provided per 51 reports by companies from 2 notifications to the ECHA C&L Inventory.; Reported as not meeting GHS hazard criteria per 50 of 51 reports by companies.; There is 1 notification provided by 1 of 51 reports by companies with hazard statement code(s).; Information may vary between notifications depending on impurities, additives, and other factors. The percentage value in parenthesis indicates the notified classification ratio from companies that provide hazard codes. Only hazard codes with percentage values above 10% are shown. For more detailed information, please visit ECHA C&L website. Source: European Chemicals Agency (ECHA)

Mapped by: Existing checksum-valid CAS to unique PubChem CID match. Retrieved: 2026-08-31. Open source record

Scientific classifications and hazard annotations provide context and do not replace the market-specific regulatory decision shown above.

Additional source coverage and match status
SourceResultChecked
EMBL-EBI ChEBIExact match2026-08-31
NIH PubChem PUG-ViewExact match2026-08-31

A recorded no-match is useful evidence that the source was checked; it is not a claim that the substance does not exist elsewhere.

Retrieved from NIH PubChem on 2026-08-31 by checksum-valid CAS matching. Chemical properties do not replace the regulatory decision on this page.

Inventory details for CYCLOHEPTASILOXANE

INCI name

CYCLOHEPTASILOXANE

Description

Tetradecamethylcycloheptasiloxane

Record provenance

Inventory reference
55546
Imported identity
CYCLOHEPTASILOXANE
Source update
15/10/2010
European Commission CosIng source notes

Key data

Restriction
Function
ANTICAKING
Preventing agglomeration of particulate solids into lumps or hard masses (cohesive cake), thus allowing free flow of particles.
SKIN CONDITIONING
Maintaining the skin in good condition.
SKIN CONDITIONING - EMOLLIENT
Acting as lubricants on the skin surface providing the skin with a soft and smooth appearance.
SOLVENT
Dissolving other components of cosmetics. Solvents are usually liquids (aqueous and nonaqueous).

Official EU ingredient-name evidence

The ingredient name exactly matches the official 2025 EU glossary of common ingredient names.

Ingredients with overlapping formulation functions

Additional official and scientific sources

11 external databases to check this identity in

How CYCLOHEPTASILOXANE appears in the CosIng inventory

The CosIng inventory lists CYCLOHEPTASILOXANE as a cosmetic ingredient and this page links it to 0 annex records. The inventory entry captures names and identifiers, while the annex records show where the substance is prohibited, restricted or positively listed in EU cosmetics law.

CYCLOHEPTASILOXANE is also tagged with 4 cosmetic functions in the official data. Function labels describe intended use, but they do not replace regulatory review of linked annex records before formulation or labelling work.

Frequently asked questions

CYCLOHEPTASILOXANE is listed in the EU CosIng ingredient inventory with no direct annex restriction records linked at this time. Absence of an annex link does not guarantee unrestricted use — always verify against the current official CosIng database before formulating.

According to the EU CosIng inventory, CYCLOHEPTASILOXANE carries the following function designation(s):

CAS 107-50-6 may appear across multiple EU annex records. Viewing the CAS lookup page shows all Annex II–VI entries sharing this identifier, which is useful for identifying cross-annex regulatory status of the same chemical substance.

Use the INCI Checker to screen a full ingredient list across selected markets, or compare this substance across all supported market datasets.

Source note for CYCLOHEPTASILOXANE

This page reproduces the CosIng inventory entry for CYCLOHEPTASILOXANE from public European Commission cosmetic ingredient materials and shows linked identifiers even when no direct annex match is currently attached.

Use this inventory page to research CYCLOHEPTASILOXANE and compare linked records, but verify restrictions and legal status against the current official source text and law before making regulatory decisions.

Tools & next steps

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