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InventoryRef 5527015/10/2010

CHOLESTERYL SUCCINATE

Cholesteryl Succinate is the monoester of Cholesterol and Succinic acid

CHOLESTERYL SUCCINATE is listed in the EU CosIng inventory, but no direct annex records are linked on this page yet.

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Regulatory evidence by market

No rule for this ingredient has been imported for any of the 13 markets tracked here.

That describes this inventory, not the law. No imported rule is not evidence that an ingredient is permitted: a rule may exist under another name or identifier, or in a dataset not yet imported here.

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Chemical identity and properties

PubChem 2D chemical structure for CAS 1510-21-0

CAS 1510-21-0PubChem CID 65082

Cholesteryl hemisuccinate

Cholesteryl hemisuccinate is a dicarboxylic acid monoester resulting from the formal condensation of the hydroxy group of cholesterol with one of the carboxy groups of succinic acid. A detergent that is often used to replace cholesterol in protein crystallography, biochemical studies of proteins, and pharmacology. It has a role as a detergent. It is a cholestane ester, a hemisuccinate and a dicarboxylic acid monoester. It is functionally related to a cholesterol. — ChEBI

IUPAC name: 4-[[(3S,8S,9S,10R,13R,14S,17R)-10,13-dimethyl-17-[(2R)-6-methylheptan-2-yl]-2,3,4,7,8,9,11,12,14,15,16,17-dodecahydro-1H-cyclopenta[a]phenanthren-3-yl]oxy]-4-oxobutanoic acid

Molecular formula: C31H50O4
Molecular weight: 486.7 g/mol
Exact mass: 486.37091007 Da
XLogP3: 8.5
Topological polar surface area: 63.6 Å²
Hydrogen-bond donors: 1
Hydrogen-bond acceptors: 4
Covalent units: 1
Defined stereocentres: 8

Also known as

Cholesteryl succinatemonocholesteryl succinateT3J4KS4201CHEBI:138742NSC-628321RefChem:576072216-148-6Cholesterol Hydrogen Succinate

16 more reported names

Cholesterol hemisuccinateCHEMSCholesteryl hydrogen succinateCholest-5-en-3beta-yl hydrogen succinateSuccinic Acid Monocholesterol Ester3-cholesteryloxycarbonylpropanoic acidCholest-5-en-3-ol (3.beta.)-, hydrogen butanedioateCholest-5-en-3-ol (3beta)-, 3-(hydrogen butanedioate)Cholesterylhemisuccinate3beta-Hydroxy-5-cholestene 3-hemisuccinateUNII-T3J4KS42013-(3-Cholesteryloxycarbonyl)propionic Acid; 3-Cholesteryloxycarbonylpropanoic Acid;3-[(Cholest-5-en-3ss-yl)oxycarbonyl]propionic Acid; Cholesterol Hemisuccinate;Y01EINECS 216-148-6NSC 628321

Open full PubChem record PubChem annotations 3D structure image

External database identifiers

ChEBI:CHEBI:138742
EPA DTXSID:DTXSID10934145
PubMed:9067481

Retrieved from NIH PubChem on 2026-08-31 by checksum-valid CAS matching. Chemical properties do not replace the regulatory decision on this page.

Inventory details for CHOLESTERYL SUCCINATE

INCI name

CHOLESTERYL SUCCINATE

Description

Cholesteryl Succinate is the monoester of Cholesterol and Succinic acid

Record provenance

Inventory reference: 55270
Imported identity: CHOLESTERYL SUCCINATE
Source update: 15/10/2010

European Commission CosIng source notes

Annex records for CHOLESTERYL SUCCINATE

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Key data

CAS

1510-21-0

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Restriction

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Function

SKIN CONDITIONING: Maintaining the skin in good condition.
SKIN CONDITIONING - EMOLLIENT: Acting as lubricants on the skin surface providing the skin with a soft and smooth appearance.

Official EU ingredient-name evidence

The ingredient name exactly matches the official 2025 EU glossary of common ingredient names.

#6263 · CHOLESTERYL SUCCINATE

Ingredients with overlapping formulation functions

CHOLESTERYL LACTATESKIN CONDITIONING - EMOLLIENT; HUMECTANT; SKIN CONDITIONING - HUMECTANT; SKIN CONDITIONING - OCCLUS…

CHOLESTERYL MACADAMIATESKIN CONDITIONING, SKIN CONDITIONING - EMOLLIENT, VISCOSITY CONTROLLING

CHOLESTERYL NONANOATESKIN CONDITIONING - EMOLLIENT

CHOLESTERYL STEARATESKIN CONDITIONING, SKIN CONDITIONING - EMOLLIENT, SURFACTANT - EMULSIFYING, VISCOSITY CONTROLLING

CHONDRACANTHUS TENELLUS EXTRACTSKIN CONDITIONING, SKIN CONDITIONING - EMOLLIENT

CHONDRUS ELATUS EXTRACTSKIN CONDITIONING, SKIN CONDITIONING - EMOLLIENT

CHROMULINA OCHROMONOIDES EXTRACTSKIN CONDITIONING, SKIN CONDITIONING - EMOLLIENT

CHRYSANTHELLUM INDICUM FLOWER WATERANTIMICROBIAL, ANTIOXIDANT, ASTRINGENT, SKIN CONDITIONING, SKIN CONDITIONING - EMOLLIENT, SKIN PROT…

Additional official and scientific sources

11 external databases to check this identity in

Each link searches that source for this identity. What each source is, and its legal weight

ECHA CHEM / Information on chemicals PubChem PUG REST EU Safety Gate cosmetic product alerts ECHA CHEM US EPA CompTox Cosmetic Ingredient Review safety assessments FDA Global Substance Registration System ILO/WHO International Chemical Safety Cards Japan NITE-CHRIP NIOSH Pocket Guide to Chemical Hazards OECD eChemPortal

How CHOLESTERYL SUCCINATE appears in the CosIng inventory

The CosIng inventory lists CHOLESTERYL SUCCINATE as a cosmetic ingredient and this page links it to 0 annex records. The inventory entry captures names and identifiers, while the annex records show where the substance is prohibited, restricted or positively listed in EU cosmetics law.

CHOLESTERYL SUCCINATE is also tagged with 2 cosmetic functions in the official data. Function labels describe intended use, but they do not replace regulatory review of linked annex records before formulation or labelling work.

Frequently asked questions

CHOLESTERYL SUCCINATE is listed in the EU CosIng ingredient inventory with no direct annex restriction records linked at this time. Absence of an annex link does not guarantee unrestricted use — always verify against the current official CosIng database before formulating.

According to the EU CosIng inventory, CHOLESTERYL SUCCINATE carries the following function designation(s):

CAS 1510-21-0 may appear across multiple EU annex records. Viewing the CAS lookup page shows all Annex II–VI entries sharing this identifier, which is useful for identifying cross-annex regulatory status of the same chemical substance.

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Source note for CHOLESTERYL SUCCINATE

This page reproduces the CosIng inventory entry for CHOLESTERYL SUCCINATE from public European Commission cosmetic ingredient materials and shows linked identifiers even when no direct annex match is currently attached.

Use this inventory page to research CHOLESTERYL SUCCINATE and compare linked records, but verify restrictions and legal status against the current official source text and law before making regulatory decisions.

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