What does the restriction note for CALCIUM FRUCTOBORATE mean?

The restriction field for CALCIUM FRUCTOBORATE reads: II/1396. This is the restriction note from the CosIng inventory. For authoritative conditions and limits, always refer to the linked annex entries.

What other records share CAS 250141-42-5?

CAS 250141-42-5 may appear across multiple EU annex records. The CAS lookup page shows all Annex II–VI entries sharing this identifier, useful for identifying cross-annex regulatory status of the same chemical substance.

How do I check if my formula contains CALCIUM FRUCTOBORATE?

Use the INCI Checker to screen a full ingredient list across selected markets, or use the substance market comparison to review this identity across all supported market datasets.

InventoryRef 5518029/07/2020

CALCIUM FRUCTOBORATE

Calcium Fructoborate is the calcium salt of the reaction product of Boric Acid and Fructose

CALCIUM FRUCTOBORATE is linked to 1 EU annex record on this page. Inventory note: II/1396.

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Regulatory evidence by market

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Market	Evidence status	Records	Source language
European Union	Evidence linked Prohibited entry found Open this evidence	1	English and EU languages
Great Britain	Source mapped Official source mapped; ingredient rule not imported	0	English
Canada	Source mapped Official source mapped; ingredient rule not imported	0	English and French
New Zealand	Source mapped Official source mapped; ingredient rule not imported	0	English
ASEAN	Source mapped Official source mapped; ingredient rule not imported	0	English and national languages
China	Source mapped Official source mapped; ingredient rule not imported	0	Chinese with selected English material
Japan	Source mapped Official source mapped; ingredient rule not imported	0	Japanese; official English translation available
South Korea	Source mapped Official source mapped; ingredient rule not imported	0	Korean with some English names
United States	Source mapped Official source mapped; ingredient rule not imported	0	English
Australia	Source mapped Official source mapped; ingredient rule not imported	0	English
Brazil	Source mapped Official source mapped; ingredient rule not imported	0	Portuguese with INCI crosswalks
India	Source mapped Official source mapped; ingredient rule not imported	0	English and Hindi
Saudi Arabia	Source mapped Official source mapped; ingredient rule not imported	0	Arabic and English

Chemical identity and properties

PubChem 2D chemical structure for CAS 250141-42-5

CAS 250141-42-5PubChem CID 9962298

Calcium fructoborate

IUPAC name: calcium bis((1S,1'S,5R,5'R,7R,7'R,8S,8'S)-5,5',7,7'-tetrakis(hydroxymethyl)-3,3'-spirobi[2,4,6-trioxa-3-boranuidabicyclo[3.3.0]octane]-8,8'-diol)

Molecular formula: C24H40B2CaO24
Molecular weight: 774.3 g/mol
Exact mass: 774.1721533 Da
Topological polar surface area: 354.0 Å²
Hydrogen-bond donors: 12
Hydrogen-bond acceptors: 26
Covalent units: 3
Defined stereocentres: 16

Also known as

7EW2EZ38LSRefChem:917879Borate(1-), bis(beta-D-fructofuranosato(2-)-kappaO2,kappaO3)-, calcium (2:1), (T-4)-CALCIUM FRUCTOBORATE [WHO-DD]BORATE(1-), BIS(.BETA.-D-FRUCTOFURANOSATO(2-)-.KAPPA.O2,.KAPPA.O3)-, CALCIUM (2:1), (T-4)-calcium;(1S,1'S,5R,5'R,7R,7'R,8S,8'S)-5,5',7,7'-tetrakis(hydroxymethyl)-3,3'-spirobi[2,4,6-trioxa-3-boranuidabicyclo[3.3.0]octane]-8,8'-diol

Open full PubChem record PubChem annotations 3D structure image

External database identifiers

PubMed:35174920

Retrieved from NIH PubChem on 2026-08-31 by checksum-valid CAS matching. Chemical properties do not replace the regulatory decision on this page.

Inventory details for CALCIUM FRUCTOBORATE

INCI name

CALCIUM FRUCTOBORATE

Description

Calcium Fructoborate is the calcium salt of the reaction product of Boric Acid and Fructose

Record provenance

Inventory reference: 55180
Imported identity: CALCIUM FRUCTOBORATE
Source update: 29/07/2020

European Commission CosIng source notes

Annex records for CALCIUM FRUCTOBORATE

Annex II Restriction reference

Entry 1396

Borates, tetraborates, octaborates and boric acid salts and esters, including: Disodium octaborate …

CAS: 12008-41-2 [1]/ 12280-03-4 [2]/ 10377-81-8 [3]/ 68003-13-4 [4]/ 12712-38-8 [5]/ -[6]/ 1332-07-6 [7]/ 1330-43-4 [8]/ 12267-73-1 [9]/ 13840-56-7 [10]/ 1303-96-4 [11]/ 12179-04-3 [12]

EC: 234-541-0 [1]/ 234-541-0 [2]/ 233-829-3 [3]/ 268-109-8 [4]/ 603-184-6 [5]/ -[6]/ 215-566-6 [7]/ 215-540-4 [8]/ 235-541-3 [9]/ 237-560-2 [10]/ 215-540-4 [11]/ 215-540-4 [12]

Key data

CAS

250141-42-5

—

Restriction

II/1396

Function

SKIN CONDITIONING - HUMECTANT: Increasing the water content of the top layers of the skin. Humectants are primarily hygroscopic agents drawing moisture from the surrounding air.

Official EU ingredient-name evidence

The ingredient name exactly matches the official 2025 EU glossary of common ingredient names.

#4932 · CALCIUM FRUCTOBORATE

Ingredients with overlapping formulation functions

BUTENEONE NAPHTHALENEDIOLHAIR CONDITIONING; OXIDISING; SKIN PROTECTING; SKIN CONDITIONING - HUMECTANT

C14-17 TRIGLYCERIDESSKIN CONDITIONING - HUMECTANT; SKIN CONDITIONING - MISCELLANEOUS

C20-C30 HYDROXYACIDSKIN CONDITIONING - EMOLLIENT; EMULSION STABILISING; SKIN PROTECTING; SKIN CONDITIONING - HUMECTANT

CAESIA PARVIFLORA ROOT EXTRACTSKIN CONDITIONING - EMOLLIENT; SKIN CONDITIONING - HUMECTANT

CALCIUM HYALURONATESKIN PROTECTING; SKIN CONDITIONING - HUMECTANT

CALIDIFONTIBACTER INDICUS FERMENT EXTRACT FILTRATESKIN CONDITIONING - HUMECTANT

CALIDIFONTIBACTER INDICUS LYSATESKIN CONDITIONING - HUMECTANT

CALOPHYLLUM BRASILIENSE SEED OILFILM FORMING; HAIR CONDITIONING; SKIN CONDITIONING - HUMECTANT

Additional official and scientific sources

11 external databases to check this identity in

Each link searches that source for this identity. What each source is, and its legal weight

ECHA CHEM / Information on chemicals PubChem PUG REST EU Safety Gate cosmetic product alerts ECHA CHEM US EPA CompTox Cosmetic Ingredient Review safety assessments FDA Global Substance Registration System ILO/WHO International Chemical Safety Cards Japan NITE-CHRIP NIOSH Pocket Guide to Chemical Hazards OECD eChemPortal

How CALCIUM FRUCTOBORATE appears in the CosIng inventory

The CosIng inventory lists CALCIUM FRUCTOBORATE as a cosmetic ingredient and this page links it to 1 annex record. The inventory entry captures names and identifiers, while the annex record shows where the substance is prohibited, restricted or positively listed in EU cosmetics law.

CALCIUM FRUCTOBORATE is also tagged with 1 cosmetic function in the official data. Function labels describe intended use, but they do not replace regulatory review of linked annex records before formulation or labelling work.

Frequently asked questions

CALCIUM FRUCTOBORATE appears in the EU CosIng inventory and has linked annex records. Check the annex records above for applicable restrictions, concentration limits and conditions of use. Annex II listing means prohibited; Annex III means restricted; Annexes IV, V and VI mean permitted under specified conditions.

The restriction field for CALCIUM FRUCTOBORATE reads: "II/1396". This is the restriction note recorded in the CosIng inventory for this ingredient. For authoritative conditions and limits, always refer to the linked annex entries above.

According to the EU CosIng inventory, CALCIUM FRUCTOBORATE carries the following function designation(s):

SKIN CONDITIONING - HUMECTANT

CAS 250141-42-5 may appear across multiple EU annex records. Viewing the CAS lookup page shows all Annex II–VI entries sharing this identifier, which is useful for identifying cross-annex regulatory status of the same chemical substance.

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Source note for CALCIUM FRUCTOBORATE

This page combines the CosIng inventory entry for CALCIUM FRUCTOBORATE with 1 linked Annex II–VI record from the local dataset built from public European Commission cosmetic ingredient materials.

Use this inventory page to research CALCIUM FRUCTOBORATE and compare linked records, but verify restrictions and legal status against the current official source text and law before making regulatory decisions.

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