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CAS 10438-94-5 may appear across multiple EU annex records. The CAS lookup page shows all Annex II–VI entries sharing this identifier, useful for identifying cross-annex regulatory status of the same chemical substance.

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InventoryRef 5513915/10/2010

CAPRYLYL GLYCERYL ETHER

1,2-Propanediol, 3-(Octyloxy)-

CAPRYLYL GLYCERYL ETHER is listed in the EU CosIng inventory, but no direct annex records are linked on this page yet.

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Regulatory evidence by market

No rule for this ingredient has been imported for any of the 13 markets tracked here.

That describes this inventory, not the law. No imported rule is not evidence that an ingredient is permitted: a rule may exist under another name or identifier, or in a dataset not yet imported here.

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Chemical identity and properties

PubChem 2D chemical structure for CAS 10438-94-5

CAS 10438-94-5PubChem CID 112041

Octyl-sepharose CL-4B

IUPAC name: 3-octoxypropane-1,2-diol

Molecular formula: C11H24O3
Molecular weight: 204.31 g/mol
Exact mass: 204.17254462 Da
XLogP3: 2.2
Topological polar surface area: 49.7 Å²
Hydrogen-bond donors: 2
Hydrogen-bond acceptors: 3
Covalent units: 1
Defined stereocentres: 0

Also known as

Octyl-sepharoseOctylagarose CL-4BOctylsepharose CL-4BRefChem:5737873-(octyloxy)propane-1,2-diol1,2-Propanediol, 3-(octyloxy)-caprylyl glyceryl ether3-(Octyloxy)-1,2-propanediol

16 more reported names

1-Glyceryloctyl etheroctadioloctyl glyceryl etherMI97BW74XZGLYCEROL 1-OCTYL ETHER3-OCTYLOXY-PROPANE-1,2-DIOL3-octyloxypropane-1,2-diol1-O-OctylglycerolGlycerin alpha-octyl etherUNII-MI97BW74XZ3-octyloxy-1,2-propanediolOctyl Agarose 4B-CL1-octyl glyceryl ethermonooctyl glyceryl ether3-(Octyloxy)propane-12-diolGLYCERIN 1-OCTYL ETHER

Open full PubChem record PubChem annotations 3D structure image

External database identifiers

ChEMBL:CHEMBL1974894
EPA DTXSID:DTXSID50874273

Evidence from additional scientific databases

NIH PubChem PUG-View

Exact identifier match112041

Attributed physical-property, hazard, environmental and use annotations.

Signal: Danger Source: European Chemicals Agency (ECHA)
GHS Hazard Statements: H315 (100%): Causes skin irritation [Warning Skin corrosion/irritation]; H318 (100%): Causes serious eye damage [Danger Serious eye damage/eye irritation] Source: European Chemicals Agency (ECHA)
Precautionary Statement Codes: P264, P264+P265, P280, P302+P352, P305+P354+P338, P317, P321, P332+P317, and P362+P364 (click each P-code to see the statement) Source: European Chemicals Agency (ECHA)
ECHA C&L Notifications Summary: Aggregated GHS information provided per 2 reports by companies from 1 notifications to the ECHA C&L Inventory. Each notification may be associated with multiple companies.; Information may vary between notifications depending on impurities, additives, and other factors. The percentage value in parenthesis indicates the notified classification ratio from companies that provide hazard codes. Only hazard codes with percentage values above 10% are shown. For more detailed information, please visit ECHA C&L website. Source: European Chemicals Agency (ECHA)

Cosmetic Ingredient Review Finding(s): Safe in the present practices of use and concentration. Ingredient, concentration, and use information are available in documents discoverable at https://cir-reports.cir-safety.org Source: Cosmetic Ingredient Review (CIR)

Cosmetic Ingredient Review Link: CIR ingredient: Caprylyl Glyceryl Ether Source: Cosmetic Ingredient Review (CIR)
Sources/Uses: Used for hydrophobic interaction chromatography (HIC); [GE Healthcare Life Sciences] Source: Haz-Map, Information on Hazardous Chemicals and Occupational Diseases

Mapped by: Existing checksum-valid CAS to unique PubChem CID match. Retrieved: 2026-08-31. Open source record

Scientific classifications and hazard annotations provide context and do not replace the market-specific regulatory decision shown above.

Additional source coverage and match status

Source	Result	Checked
EMBL-EBI ChEBI	No exact record	2026-08-31
NIH PubChem PUG-View	Exact match	2026-08-31

A recorded no-match is useful evidence that the source was checked; it is not a claim that the substance does not exist elsewhere.

Retrieved from NIH PubChem on 2026-08-31 by checksum-valid CAS matching. Chemical properties do not replace the regulatory decision on this page.

Inventory details for CAPRYLYL GLYCERYL ETHER

INCI name

CAPRYLYL GLYCERYL ETHER

Description

1,2-Propanediol, 3-(Octyloxy)-

Record provenance

Inventory reference: 55139
Imported identity: CAPRYLYL GLYCERYL ETHER
Source update: 15/10/2010

European Commission CosIng source notes

Annex records for CAPRYLYL GLYCERYL ETHER

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Key data

CAS

10438-94-5

—

Restriction

—

Function

CLEANSING: Helping to keep the body surface clean.
SURFACTANT - CLEANSING: Wetting body surfaces, emulsifying or solubilizing oils, and suspending soil (generally, such ingredients contribute to the foaming and lathering properties of cleansing products).
SURFACTANT - FOAM BOOSTING: Increasing foaming capacity and/or stabilizing foams in general.

Official EU ingredient-name evidence

The ingredient name exactly matches the official 2025 EU glossary of common ingredient names.

#5399 · CAPRYLYL GLYCERYL ETHER

Ingredients with overlapping formulation functions

CAPRYL/CAPRAMIDOPROPYL BETAINEANTISTATIC, CLEANSING, HAIR CONDITIONING, SKIN CONDITIONING, SURFACTANT - CLEANSING, SURFACTANT - F…

CAPRYL/LAURYL WHEAT BRAN/STRAW GLYCOSIDESCLEANSING, LIGHT STABILIZER, SURFACTANT - CLEANSING, SURFACTANT - EMULSIFYING, SURFACTANT - FOAM BO…

CAPRYLIC/PCA GLYCERIDESANTISTATIC, HAIR CONDITIONING, SURFACTANT - EMULSIFYING, SURFACTANT - FOAM BOOSTING

CAPRYLOYL/CAPROYL METHYL GLUCAMIDESKIN CONDITIONING, SURFACTANT - CLEANSING, SURFACTANT - EMULSIFYING, SURFACTANT - FOAM BOOSTING

CAPRYLYL/CAPRYL WHEAT BRAN/STRAW GLYCOSIDESCLEANSING, EMULSION STABILISING, SURFACTANT - CLEANSING, SURFACTANT - EMULSIFYING, SURFACTANT - FOA…

CARNITINEANTISTATIC, CLEANSING, HAIR CONDITIONING, SKIN CONDITIONING, SURFACTANT - CLEANSING, SURFACTANT - F…

CETEARYL ALCOHOLEMULSION STABILISING, OPACIFYING, SKIN CONDITIONING - EMOLLIENT, SURFACTANT - CLEANSING, SURFACTANT…

CETYL ALCOHOLEMULSION STABILISING, FRAGRANCE, OPACIFYING, SKIN CONDITIONING - EMOLLIENT, SURFACTANT - CLEANSING,…

Additional official and scientific sources

11 external databases to check this identity in

Each link searches that source for this identity. What each source is, and its legal weight

ECHA CHEM / Information on chemicals PubChem PUG REST EU Safety Gate cosmetic product alerts ECHA CHEM US EPA CompTox Cosmetic Ingredient Review safety assessments FDA Global Substance Registration System ILO/WHO International Chemical Safety Cards Japan NITE-CHRIP NIOSH Pocket Guide to Chemical Hazards OECD eChemPortal

How CAPRYLYL GLYCERYL ETHER appears in the CosIng inventory

The CosIng inventory lists CAPRYLYL GLYCERYL ETHER as a cosmetic ingredient and this page links it to 0 annex records. The inventory entry captures names and identifiers, while the annex records show where the substance is prohibited, restricted or positively listed in EU cosmetics law.

CAPRYLYL GLYCERYL ETHER is also tagged with 3 cosmetic functions in the official data. Function labels describe intended use, but they do not replace regulatory review of linked annex records before formulation or labelling work.

Frequently asked questions

CAPRYLYL GLYCERYL ETHER is listed in the EU CosIng ingredient inventory with no direct annex restriction records linked at this time. Absence of an annex link does not guarantee unrestricted use — always verify against the current official CosIng database before formulating.

According to the EU CosIng inventory, CAPRYLYL GLYCERYL ETHER carries the following function designation(s):

CAS 10438-94-5 may appear across multiple EU annex records. Viewing the CAS lookup page shows all Annex II–VI entries sharing this identifier, which is useful for identifying cross-annex regulatory status of the same chemical substance.

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Source note for CAPRYLYL GLYCERYL ETHER

This page reproduces the CosIng inventory entry for CAPRYLYL GLYCERYL ETHER from public European Commission cosmetic ingredient materials and shows linked identifiers even when no direct annex match is currently attached.

Use this inventory page to research CAPRYLYL GLYCERYL ETHER and compare linked records, but verify restrictions and legal status against the current official source text and law before making regulatory decisions.

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