Is CARNITINE HCL safe to use in EU cosmetics?

CARNITINE HCL is listed in the EU CosIng ingredient inventory with no direct annex restriction records linked at this time. Always verify against the current official CosIng database before formulating.

What other records share CAS 6645-46-1?

CAS 6645-46-1 may appear across multiple EU annex records. The CAS lookup page shows all Annex II–VI entries sharing this identifier, useful for identifying cross-annex regulatory status of the same chemical substance.

How do I check if my formula contains CARNITINE HCL?

Use the INCI Checker to screen a full ingredient list across selected markets, or use the substance market comparison to review this identity across all supported market datasets.

InventoryRef 5508515/10/2010

CARNITINE HCL

1-Propanaminium, 3-Carboxy-1-, Hydroxyl-N,N,N-Trimethyl-, Chloride

CARNITINE HCL is listed in the EU CosIng inventory, but no direct annex records are linked on this page yet.

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Regulatory evidence by market

No rule for this ingredient has been imported for any of the 13 markets tracked here.

That describes this inventory, not the law. No imported rule is not evidence that an ingredient is permitted: a rule may exist under another name or identifier, or in a dataset not yet imported here.

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Chemical identity and properties

PubChem 2D chemical structure for CAS 6645-46-1

CAS 6645-46-1PubChem CID 656657

Levocarnitine Chloride

The CIR Expert Panel concluded the following ingredients are safe in the present practices of use and concentration described in the safety assessment when formulated to be non-irritating...Carnitine HCl... — Cosmetic Ingredient Review (CIR)

IUPAC name: [(2R)-3-carboxy-2-hydroxypropyl]-trimethylazanium chloride

Molecular formula: C7H16ClNO3
Molecular weight: 197.66 g/mol
Exact mass: 197.0818711 Da
Topological polar surface area: 57.5 Å²
Hydrogen-bond donors: 2
Hydrogen-bond acceptors: 4
Covalent units: 2
Defined stereocentres: 1

Also known as

L-Carnitine chlorideJ3Y5E6IKS3Carnitine HCllevocarnitine hydrochloride(R)-Carnitine hydrochlorideCarnitine L-form hydrochlorideLC-80EINECS 229-663-6

16 more reported names

CARNITINE HCL [INCI]Levocarnitine chloride (JAN)CARNITINE HYDROCHLORIDE, L-LEVOCARNITINE CHLORIDE [JAN]l-(3-Carboxy-2-hydroxypropyl)trimethylammonium chloride(-)-(3-Carboxy-2-hydroxypropyl)trimethylammonium chloride(R)-(3-Carboxy-2-hydroxypropyl)trimethylammonium chlorideSELTZER CHEMICALS L-CARNITINE HCLLEVOCARNITINE HYDROCHLORIDE [MART.](R)-3-Carboxy-2-hydroxy-N,N,N-trimethyl-1-propanaminium chlorideLEVOCARNITINE HYDROCHLORIDE [WHO-DD]1-Propanaminium, 3-carboxy-2-hydroxy-N,N,N-trimethyl-, chloride, (R)-AMMONIUM, (3-CARBOXY-2-HYDROXYPROPYL)TRIMETHYL-, CHLORIDE, (-)-(2R)-3-CARBOXY-2-HYDROXY-N,N,N-TRIMETHYL-1-PROPANAMINIUM INNER SALT HYDROCHLORIDELEVOCARNITINE HYDROCHLORIDE (MART.)L-cartin

Open full PubChem record PubChem annotations 3D structure image

External database identifiers

ChEMBL:CHEMBL1876404
EPA DTXSID:DTXSID701014449

Retrieved from NIH PubChem on 2026-08-31 by checksum-valid CAS matching. Chemical properties do not replace the regulatory decision on this page.

Inventory details for CARNITINE HCL

INCI name

CARNITINE HCL

Description

1-Propanaminium, 3-Carboxy-1-, Hydroxyl-N,N,N-Trimethyl-, Chloride

Record provenance

Inventory reference: 55085
Imported identity: CARNITINE HCL
Source update: 15/10/2010

European Commission CosIng source notes

Annex records for CARNITINE HCL

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Key data

CAS

6645-46-1

229-663-6

Restriction

—

Function

HUMECTANT: Retaining and/or preserving the moisture in a product during use.
SKIN CONDITIONING: Maintaining the skin in good condition.

Official EU ingredient-name evidence

The ingredient name exactly matches the official 2025 EU glossary of common ingredient names.

#5514 · CARNITINE HCl

Ingredients with overlapping formulation functions

CARBOXYMETHYL CHITOSAN SUCCINAMIDEFILM FORMING, HAIR CONDITIONING, HUMECTANT, SKIN CONDITIONING

CARBOXYMETHYL LEVANHUMECTANT, SKIN CONDITIONING

CARICA PAPAYA FRUIT JUICEHUMECTANT, SKIN CONDITIONING

CARICA PAPAYA SEED OILHUMECTANT, SKIN CONDITIONING

CARPINUS TURCZANINOWII EXTRACTHUMECTANT, SKIN CONDITIONING, SKIN PROTECTING

CARTHAMUS TINCTORIUS CALLUS EXTRACTANTIMICROBIAL, ANTIOXIDANT, HAIR CONDITIONING, HUMECTANT, SKIN CONDITIONING, SKIN PROTECTING

CARYOCAR BRASILIENSE FRUIT/LEAF EXTRACTHUMECTANT

CARYOCAR CORIACEUM SEED OILHUMECTANT, SKIN CONDITIONING, SKIN CONDITIONING - EMOLLIENT, SKIN PROTECTING

Additional official and scientific sources

11 external databases to check this identity in

Each link searches that source for this identity. What each source is, and its legal weight

ECHA CHEM / Information on chemicals PubChem PUG REST EU Safety Gate cosmetic product alerts ECHA CHEM US EPA CompTox Cosmetic Ingredient Review safety assessments FDA Global Substance Registration System ILO/WHO International Chemical Safety Cards Japan NITE-CHRIP NIOSH Pocket Guide to Chemical Hazards OECD eChemPortal

How CARNITINE HCL appears in the CosIng inventory

The CosIng inventory lists CARNITINE HCL as a cosmetic ingredient and this page links it to 0 annex records. The inventory entry captures names and identifiers, while the annex records show where the substance is prohibited, restricted or positively listed in EU cosmetics law.

CARNITINE HCL is also tagged with 2 cosmetic functions in the official data. Function labels describe intended use, but they do not replace regulatory review of linked annex records before formulation or labelling work.

Frequently asked questions

CARNITINE HCL is listed in the EU CosIng ingredient inventory with no direct annex restriction records linked at this time. Absence of an annex link does not guarantee unrestricted use — always verify against the current official CosIng database before formulating.

According to the EU CosIng inventory, CARNITINE HCL carries the following function designation(s):

CAS 6645-46-1 may appear across multiple EU annex records. Viewing the CAS lookup page shows all Annex II–VI entries sharing this identifier, which is useful for identifying cross-annex regulatory status of the same chemical substance.

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Source note for CARNITINE HCL

This page reproduces the CosIng inventory entry for CARNITINE HCL from public European Commission cosmetic ingredient materials and shows linked identifiers even when no direct annex match is currently attached.

Use this inventory page to research CARNITINE HCL and compare linked records, but verify restrictions and legal status against the current official source text and law before making regulatory decisions.

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Tools & next steps

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