Is BORNANEDIONE safe to use in EU cosmetics?

BORNANEDIONE is listed in the EU CosIng ingredient inventory with no direct annex restriction records linked at this time. Always verify against the current official CosIng database before formulating.

What other records share CAS 10373-78-1?

CAS 10373-78-1 may appear across multiple EU annex records. The CAS lookup page shows all Annex II–VI entries sharing this identifier, useful for identifying cross-annex regulatory status of the same chemical substance.

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InventoryRef 5473815/10/2010

BORNANEDIONE

Bicyclo[2.2.1]heptane-2,3-dione, 1,7,7-trimethyl-

BORNANEDIONE is listed in the EU CosIng inventory, but no direct annex records are linked on this page yet.

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Regulatory evidence by market

No rule for this ingredient has been imported for any of the 13 markets tracked here.

That describes this inventory, not the law. No imported rule is not evidence that an ingredient is permitted: a rule may exist under another name or identifier, or in a dataset not yet imported here.

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Chemical identity and properties

PubChem 2D chemical structure for CAS 10373-78-1

CAS 10373-78-1PubChem CID 25208

Bornane-2,3-dione

Bornane-2,3-dione is a bornane monoterpenoid that is bicyclo[2.2.1]heptane substituted by methyl groups at positions 1, 7 and 7 and oxo groups at positions 2 and 3. It is a bornane monoterpenoid and a carbobicyclic compound. — ChEBI

IUPAC name: 1,7,7-trimethylbicyclo[2.2.1]heptane-2,3-dione

Molecular formula: C10H14O2
Molecular weight: 166.22 g/mol
Exact mass: 166.099379685 Da
XLogP3: 1.5
Topological polar surface area: 34.1 Å²
Hydrogen-bond donors: 0
Hydrogen-bond acceptors: 2
Covalent units: 1
Defined stereocentres: 0

Also known as

Camphorquinone2,3-Bornanedione465-29-2Camphor quinoneCamphoquinoneCHEBI:346071,7,7-trimethylbicyclo[2.2.1]heptane-2,3-dione bornane-2,3-dione1,7,7-TRIMETHYLBICYCLO(2.2.1)HEPTANE-2,3-DIONE

16 more reported names

1,7,7-trimethylbicyclo(2.2.1)heptane-2,3-dione bornane-2,3-dioneRefChem:570022207-363-6DL-CAMPHORQUINONE(+/-)-CamphorquinoneBicyclo[2.2.1]heptane-2,3-dione, 1,7,7-trimethyl-dl-Camphoroquinone1,7,7-trimethylnorbornane-2,3-dione( inverted exclamation markA)-CamphorquinoneBicyclo[2.2.1]heptane-2,3-dione, 1,7,7-trimethyl-, (1R)-CAMPHOREQUINONEBicyclo[2.2.1]heptane-2, 1,7,7-trimethyl-NSC-285(1R)-(-)-2,3-Bornanedione3-Ketocamphor(+/-) camphorquinone

Open full PubChem record PubChem annotations 3D structure image

External database identifiers

ChEBI:CHEBI:34607
ChEMBL:CHEMBL301431
EPA DTXSID:DTXSID7049394
PubMed:23083514
PubMed:23032211
PubMed:22940188
PubMed:22641438
PubMed:22615635
PubMed:22606202
PubMed:22578661
PubMed:22548062
PubMed:22509202
PubMed:22509120
PubMed:22509117
PubMed:22484872

Evidence from additional scientific databases

EMBL-EBI ChEBI

Exact identifier matchCHEBI:34607

bornane-2,3-dione

A bornane monoterpenoid that is bicyclo[2.2.1]heptane substituted by methyl groups at positions 1, 7 and 7 and oxo groups at positions 2 and 3.

Formula: C10H14O2
Average mass: 166.220 g/mol
Monoisotopic mass: 166.09938 Da
Formal charge: 0

bornane monoterpenoid — is a (CHEBI:22912)
carbobicyclic compound — is a (CHEBI:36785)

bornane monoterpenoid — is a (CHEBI:22912)
carbobicyclic compound — is a (CHEBI:36785)

24430338 Source: PubMed

Additional curated names

1,7,7-trimethylbicyclo[2.2.1]heptane-2,3-dionebornane-2,3-dione2,3-bornanedionecamphoquinonecamphoroquinonecamphor quinoneCamphorquinone

Cross-references from this source

CAS: 10373-78-1 — ChemIDplus
CAS: 465-29-2 — KEGG COMPOUND
CAS: 465-29-2 — NIST Chemistry WebBook
REGISTRY_NUMBER: 1909463 — Reaxys
REGISTRY_NUMBER: 482102 — Gmelin
MANUAL_X_REF: C14515 — KEGG COMPOUND
MANUAL_X_REF: LMPR0102120030 — LIPID MAPS

Mapped by: Exact CAS cross-reference in the ChEBI compound record. Source updated: 2014-05-14. Retrieved: 2026-08-31. Open source record

NIH PubChem PUG-View

Exact identifier match25208

Attributed physical-property, hazard, environmental and use annotations.

Note: This chemical does not meet GHS hazard criteria for 11.1% (2 of 18) of reports. Source: European Chemicals Agency (ECHA)
Signal: Warning Source: European Chemicals Agency (ECHA)
GHS Hazard Statements: H315 (88.9%): Causes skin irritation [Warning Skin corrosion/irritation]; H319 (88.9%): Causes serious eye irritation [Warning Serious eye damage/eye irritation]; H335 (88.9%): May cause respiratory irritation [Warning Specific target organ toxicity, single exposure; Respiratory tract irritation] Source: European Chemicals Agency (ECHA)
Precautionary Statement Codes: P261, P264, P264+P265, P271, P280, P302+P352, P304+P340, P305+P351+P338, P319, P321, P332+P317, P337+P317, P362+P364, P403+P233, P405, and P501 (click each P-code to see the statement) Source: European Chemicals Agency (ECHA)
ECHA C&L Notifications Summary: Aggregated GHS information provided per 18 reports by companies from 3 notifications to the ECHA C&L Inventory. Each notification may be associated with multiple companies.; Reported as not meeting GHS hazard criteria per 2 of 18 reports by companies.; There are 2 notifications provided by 16 of 18 reports by companies with hazard statement code(s).; Information may vary between notifications depending on impurities, additives, and other factors. The percentage value in parenthesis indicates the notified classification ratio from companies that provide hazard codes. Only hazard codes with percentage values above 10% are shown. For more detailed information, please visit ECHA C&L website. Source: European Chemicals Agency (ECHA)

Mapped by: Existing checksum-valid CAS to unique PubChem CID match. Retrieved: 2026-08-31. Open source record

Scientific classifications and hazard annotations provide context and do not replace the market-specific regulatory decision shown above.

Additional source coverage and match status

Source	Result	Checked
EMBL-EBI ChEBI	Exact match	2026-08-31
NIH PubChem PUG-View	Exact match	2026-08-31

A recorded no-match is useful evidence that the source was checked; it is not a claim that the substance does not exist elsewhere.

Retrieved from NIH PubChem on 2026-08-31 by checksum-valid CAS matching. Chemical properties do not replace the regulatory decision on this page.

Inventory details for BORNANEDIONE

INCI name

BORNANEDIONE

Description

Bicyclo[2.2.1]heptane-2,3-dione, 1,7,7-trimethyl-

Record provenance

Inventory reference: 54738
Imported identity: BORNANEDIONE
Source update: 15/10/2010

European Commission CosIng source notes

Annex records for BORNANEDIONE

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Key data

CAS

10373-78-1

233-814-1

Restriction

—

Function

FILM FORMING: Producing (upon application) a continuous film on the skin, hair or nails.

Official EU ingredient-name evidence

The ingredient name exactly matches the official 2025 EU glossary of common ingredient names.

#3880 · BORNANEDIONE

Ingredients with overlapping formulation functions

BIS-VINYL DIPHENYL DIMETHICONEFILM FORMING, HAIR CONDITIONING, SKIN PROTECTING

BIS-VINYL DIPHENYLTRISILOXANEFILM FORMING

BIS-VINYLDIMETHICONEFILM FORMING

BIS-VINYLDIMETHICONE/PEG-10 DIMETHICONE CROSSPOLYMEREMULSION STABILISING, FILM FORMING, SKIN CONDITIONING, VISCOSITY CONTROLLING

BOSWELLIA SERRATA GUMFILM FORMING, FRAGRANCE, PERFUMING, SKIN CONDITIONING, TONIC

BRASSICA CAMPESTRIS/ALEURITES FORDI OIL COPOLYMERFILM FORMING, SKIN CONDITIONING

BUTADIENE/ACRYLONITRILE COPOLYMERFILM FORMING, VISCOSITY CONTROLLING

BUTENE/PROPYLENE COPOLYMERFILM FORMING, VISCOSITY CONTROLLING

Additional official and scientific sources

11 external databases to check this identity in

Each link searches that source for this identity. What each source is, and its legal weight

ECHA CHEM / Information on chemicals PubChem PUG REST EU Safety Gate cosmetic product alerts ECHA CHEM US EPA CompTox Cosmetic Ingredient Review safety assessments FDA Global Substance Registration System ILO/WHO International Chemical Safety Cards Japan NITE-CHRIP NIOSH Pocket Guide to Chemical Hazards OECD eChemPortal

How BORNANEDIONE appears in the CosIng inventory

The CosIng inventory lists BORNANEDIONE as a cosmetic ingredient and this page links it to 0 annex records. The inventory entry captures names and identifiers, while the annex records show where the substance is prohibited, restricted or positively listed in EU cosmetics law.

BORNANEDIONE is also tagged with 1 cosmetic function in the official data. Function labels describe intended use, but they do not replace regulatory review of linked annex records before formulation or labelling work.

Frequently asked questions

BORNANEDIONE is listed in the EU CosIng ingredient inventory with no direct annex restriction records linked at this time. Absence of an annex link does not guarantee unrestricted use — always verify against the current official CosIng database before formulating.

According to the EU CosIng inventory, BORNANEDIONE carries the following function designation(s):

FILM FORMING

CAS 10373-78-1 may appear across multiple EU annex records. Viewing the CAS lookup page shows all Annex II–VI entries sharing this identifier, which is useful for identifying cross-annex regulatory status of the same chemical substance.

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Source note for BORNANEDIONE

This page reproduces the CosIng inventory entry for BORNANEDIONE from public European Commission cosmetic ingredient materials and shows linked identifiers even when no direct annex match is currently attached.

Use this inventory page to research BORNANEDIONE and compare linked records, but verify restrictions and legal status against the current official source text and law before making regulatory decisions.

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