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InventoryRef 5429415/10/2010

ALKALINE PHOSPHATASE

Alkaline Phosphatase is an enzyme that hydrolizes esters of phosphoric acid. Specfically, Alkaline Phosphatase is used to catalyze the removal of 5'-phosphates from DNA and RNA

ALKALINE PHOSPHATASE is listed in the EU CosIng inventory, but no direct annex records are linked on this page yet.

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Regulatory evidence by market

No rule for this ingredient has been imported for any of the 13 markets tracked here.

That describes this inventory, not the law. No imported rule is not evidence that an ingredient is permitted: a rule may exist under another name or identifier, or in a dataset not yet imported here.

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Chemical identity and properties

PubChem 2D chemical structure for CAS 9001-78-9

CAS 9001-78-9PubChem CID 18985873

Alkaline Phosphatase

Alkaline Phosphatase (AP) is an oral treatment and has a very favorable side-effect profile. AP only acts locally in the colon to reduce the continuous inflammation of the colon by endotoxin from Gram-negative bacteria and extracellular ATP in UC patients. — DrugBank

IUPAC name: 2-[[1-[2-[[1-(2-aminopropanoyl)pyrrolidine-2-carbonyl]amino]acetyl]pyrrolidine-2-carbonyl]amino]-5-(diaminomethylideneamino)pentanoic acid

Molecular formula: C21H36N8O6
Molecular weight: 496.6 g/mol
Exact mass: 496.27578090 Da
XLogP3: -5.0
Topological polar surface area: 227.0 Å²
Hydrogen-bond donors: 6
Hydrogen-bond acceptors: 8
Covalent units: 1
Defined stereocentres: 0

Also known as

Phosphatase, alkalineRefChem:388781EINECS 232-631-4Phosphatase, Alkaline, from Escherichia coliOrthophosphoric-monoester phosphohydrolase (alkaline optimum)Orthophosphoricmonoester phosphohydrolase (alkaline optimum)232-631-4Phosphatase, Alkaline from Escherichia coli

8 more reported names

Enterostatin, human, mouse, ratENTEROSTATIN,HUMANAlkaline Phosphatase (ALP)ITZMJCSORYKOSI-UHFFFAOYSA-NAlkaline Phosphatase from calf intestinalPhosphatase, Alkaline from Chicken IntestinePhosphatase, Alkaline from calf intestine(Purified)(S)-2-((S)-1-(2-((S)-1-((S)-2-aminopropanoyl)pyrrolidine-2-carboxamido)acetyl)pyrrolidine-2-carboxamido)-5-((diaminomethylene)amino)pentanoic acid

Open full PubChem record PubChem annotations 3D structure image

Retrieved from NIH PubChem on 2026-08-31 by checksum-valid CAS matching. Chemical properties do not replace the regulatory decision on this page.

Inventory details for ALKALINE PHOSPHATASE

INCI name

ALKALINE PHOSPHATASE

Description

Alkaline Phosphatase is an enzyme that hydrolizes esters of phosphoric acid. Specfically, Alkaline Phosphatase is used to catalyze the removal of 5'-phosphates from DNA and RNA

Record provenance

Inventory reference: 54294
Imported identity: ALKALINE PHOSPHATASE
Source update: 15/10/2010

European Commission CosIng source notes

Annex records for ALKALINE PHOSPHATASE

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Key data

CAS

9001-78-9

232-631-4

Restriction

—

Function

SKIN CONDITIONING: Maintaining the skin in good condition.

Official EU ingredient-name evidence

The ingredient name exactly matches the official 2025 EU glossary of common ingredient names.

#1341 · ALKALINE PHOSPHATASE

Ingredients with overlapping formulation functions

ALIBERTIA PATINOI FRUIT EXTRACTHAIR CONDITIONING, SKIN CONDITIONING

ALIBERTIA PATINOI PULP EXTRACTSKIN CONDITIONING

ALISMA ORIENTALE TUBER EXTRACTSKIN CONDITIONING

ALISMA PLANTAGO AQUATICA EXTRACTSKIN CONDITIONING

ALKANNA TINCTORIA ROOT EXTRACTSKIN CONDITIONING

ALLANBLACKIA PARVIFLORA SEED BUTTERSKIN CONDITIONING, SKIN CONDITIONING - EMOLLIENT

ALLANBLACKIA STUHLMANNII SEED BUTTERSKIN CONDITIONING, SKIN CONDITIONING - EMOLLIENT, SKIN PROTECTING

ALLANTOINSKIN CONDITIONING, SKIN PROTECTING, SOOTHING

Additional official and scientific sources

11 external databases to check this identity in

Each link searches that source for this identity. What each source is, and its legal weight

ECHA CHEM / Information on chemicals PubChem PUG REST EU Safety Gate cosmetic product alerts ECHA CHEM US EPA CompTox Cosmetic Ingredient Review safety assessments FDA Global Substance Registration System ILO/WHO International Chemical Safety Cards Japan NITE-CHRIP NIOSH Pocket Guide to Chemical Hazards OECD eChemPortal

How ALKALINE PHOSPHATASE appears in the CosIng inventory

The CosIng inventory lists ALKALINE PHOSPHATASE as a cosmetic ingredient and this page links it to 0 annex records. The inventory entry captures names and identifiers, while the annex records show where the substance is prohibited, restricted or positively listed in EU cosmetics law.

ALKALINE PHOSPHATASE is also tagged with 1 cosmetic function in the official data. Function labels describe intended use, but they do not replace regulatory review of linked annex records before formulation or labelling work.

Frequently asked questions

ALKALINE PHOSPHATASE is listed in the EU CosIng ingredient inventory with no direct annex restriction records linked at this time. Absence of an annex link does not guarantee unrestricted use — always verify against the current official CosIng database before formulating.

According to the EU CosIng inventory, ALKALINE PHOSPHATASE carries the following function designation(s):

SKIN CONDITIONING

CAS 9001-78-9 may appear across multiple EU annex records. Viewing the CAS lookup page shows all Annex II–VI entries sharing this identifier, which is useful for identifying cross-annex regulatory status of the same chemical substance.

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Source note for ALKALINE PHOSPHATASE

This page reproduces the CosIng inventory entry for ALKALINE PHOSPHATASE from public European Commission cosmetic ingredient materials and shows linked identifiers even when no direct annex match is currently attached.

Use this inventory page to research ALKALINE PHOSPHATASE and compare linked records, but verify restrictions and legal status against the current official source text and law before making regulatory decisions.

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