Is VERATROLE safe to use in EU cosmetics?

VERATROLE is listed in the EU CosIng ingredient inventory with no direct annex restriction records linked at this time. Always verify against the current official CosIng database before formulating.

What other records share CAS 91-16-7?

CAS 91-16-7 may appear across multiple EU annex records. The CAS lookup page shows all Annex II–VI entries sharing this identifier, useful for identifying cross-annex regulatory status of the same chemical substance.

How do I check if my formula contains VERATROLE?

Use the INCI Checker to screen a full ingredient list across selected markets, or use the substance market comparison to review this identity across all supported market datasets.

InventoryRef 4128602/03/2011

VERATROLE

1,2-Dimethoxy-benzene; Pyrocatechol Dimethyl Ether

VERATROLE is listed in the EU CosIng inventory, but no direct annex records are linked on this page yet.

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Regulatory evidence by market

No rule for this ingredient has been imported for any of the 13 markets tracked here.

That describes this inventory, not the law. No imported rule is not evidence that an ingredient is permitted: a rule may exist under another name or identifier, or in a dataset not yet imported here.

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Chemical identity and properties

PubChem 2D chemical structure for CAS 91-16-7

CAS 91-16-7PubChem CID 7043

Veratrole

Veratrole is a dimethoxybenzene with the methoxy groups at ortho-positions. It has a role as a plant metabolite. — ChEBI

IUPAC name: 1,2-dimethoxybenzene

Molecular formula: C8H10O2
Molecular weight: 138.16 g/mol
Exact mass: 138.068079557 Da
XLogP3: 1.6
Topological polar surface area: 18.5 Å²
Hydrogen-bond donors: 0
Hydrogen-bond acceptors: 2
Covalent units: 1
Defined stereocentres: 0

Also known as

VeratrolO-DIMETHOXYBENZENEPyrocatechol dimethyl etherCatechol dimethyl ether2-MethoxyanisoleBenzene, 1,2-dimethoxy-2-DimethoxybenzolO,O-Dimethyl catechol

16 more reported names

SyntholBrenzkatechindimethyletherFEMA No. 3799Dimethylether pyrokatechinu61WJZ2Q41INSC-16934CHEBI:59114RefChem:71964202-045-3Benzene, o-dimethoxy-Methyl guaiacolGuaiacol methyletherDIMETHOXYBENZENEmethylguaiacolNSC 16934o-dimethoxy-benzene

Open full PubChem record PubChem annotations 3D structure image

External database identifiers

ChEBI:CHEBI:59114
ChEMBL:CHEMBL1668603
EPA DTXSID:DTXSID7047065
PubMed:23125757
PubMed:23125648
PubMed:23100682
PubMed:22967026
PubMed:22897232
PubMed:22871061
PubMed:22654407
PubMed:22412737
PubMed:22412733
PubMed:22354005
PubMed:22319310
PubMed:22259461

Retrieved from NIH PubChem on 2026-08-31 by checksum-valid CAS matching. Chemical properties do not replace the regulatory decision on this page.

Inventory details for VERATROLE

INCI name

VERATROLE

Description

1,2-Dimethoxy-benzene; Pyrocatechol Dimethyl Ether

Record provenance

Inventory reference: 41286
Imported identity: VERATROLE
Source update: 02/03/2011

European Commission CosIng source notes

Annex records for VERATROLE

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Key data

CAS

91-16-7

202-045-3

Restriction

—

Function

PERFUMING: Used for perfume and aromatic raw materials.

Ingredients with overlapping formulation functions

VALERIC ACIDPERFUMING

VANILLA PLANIFOLIA TINCTUREPERFUMING

VANILLOSMOPSIS ERYTHROPAPPA FLOWER/LEAF OILFRAGRANCE, PERFUMING, SKIN CONDITIONING

VERATRALDEHYDEPERFUMING

VERBENA OFFICINALIS FLOWER/LEAF WATERFLAVOURING, FRAGRANCE, PERFUMING, SKIN CONDITIONING

VERBENA OFFICINALIS LEAF ABSOLUTEPERFUMING

VERBENA OFFICINALIS LEAF RECTIFIED OILPERFUMING

VERDYL ACETATEPERFUMING

Additional official and scientific sources

11 external databases to check this identity in

Each link searches that source for this identity. What each source is, and its legal weight

ECHA CHEM / Information on chemicals PubChem PUG REST EU Safety Gate cosmetic product alerts ECHA CHEM US EPA CompTox Cosmetic Ingredient Review safety assessments FDA Global Substance Registration System ILO/WHO International Chemical Safety Cards Japan NITE-CHRIP NIOSH Pocket Guide to Chemical Hazards OECD eChemPortal

How VERATROLE appears in the CosIng inventory

The CosIng inventory lists VERATROLE as a cosmetic ingredient and this page links it to 0 annex records. The inventory entry captures names and identifiers, while the annex records show where the substance is prohibited, restricted or positively listed in EU cosmetics law.

VERATROLE is also tagged with 1 cosmetic function in the official data. Function labels describe intended use, but they do not replace regulatory review of linked annex records before formulation or labelling work.

Frequently asked questions

VERATROLE is listed in the EU CosIng ingredient inventory with no direct annex restriction records linked at this time. Absence of an annex link does not guarantee unrestricted use — always verify against the current official CosIng database before formulating.

According to the EU CosIng inventory, VERATROLE carries the following function designation(s):

PERFUMING

CAS 91-16-7 may appear across multiple EU annex records. Viewing the CAS lookup page shows all Annex II–VI entries sharing this identifier, which is useful for identifying cross-annex regulatory status of the same chemical substance.

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Source note for VERATROLE

This page reproduces the CosIng inventory entry for VERATROLE from public European Commission cosmetic ingredient materials and shows linked identifiers even when no direct annex match is currently attached.

Use this inventory page to research VERATROLE and compare linked records, but verify restrictions and legal status against the current official source text and law before making regulatory decisions.

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Tools & next steps

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