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CAS 5405-41-4 may appear across multiple EU annex records. The CAS lookup page shows all Annex II–VI entries sharing this identifier, useful for identifying cross-annex regulatory status of the same chemical substance.

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InventoryRef 3987302/03/2011

ETHYL 3-HYDROXYBUTYRATE

Ethyl 3-hydroxybutyrate

ETHYL 3-HYDROXYBUTYRATE is listed in the EU CosIng inventory, but no direct annex records are linked on this page yet.

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Regulatory evidence by market

No rule for this ingredient has been imported for any of the 13 markets tracked here.

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Chemical identity and properties

PubChem 2D chemical structure for CAS 5405-41-4

CAS 5405-41-4PubChem CID 62572

Ethyl 3-Hydroxybutyrate

Ethyl 3-hydroxybutyrate is the fatty acid ethyl ester of 3-hydroxybutyric acid. It has a role as a metabolite. It is functionally related to a 3-hydroxybutyric acid. — ChEBI

IUPAC name: ethyl 3-hydroxybutanoate

Molecular formula: C6H12O3
Molecular weight: 132.16 g/mol
Exact mass: 132.078644241 Da
XLogP3: 0.2
Topological polar surface area: 46.5 Å²
Hydrogen-bond donors: 1
Hydrogen-bond acceptors: 3
Covalent units: 1
Defined stereocentres: 0

Also known as

Ethyl beta-hydroxybutyrateButanoic acid, 3-hydroxy-, ethyl esterEthyl dl-3-hydroxybutyrateFEMA No. 3428Butyric acid, 3-hydroxy-, ethyl esterEthyl (1)-3-hydroxybutyrate3-hydroxybutyric acid ethyl esterNSC-8115

16 more reported names

NSC-42916CHEBI:876853-hydroxybutanoic acid ethyl esterRefChem:138698226-456-2252-642-8Ethyl (R)-(-)-3-hydroxybutyrateNSC 8115NSC 42916Ethyl .beta.-hydroxybutyrateDL-3-Hydroxy-n-butyrate ethyl esterEthyl3-hydroxybutyrategrape butyrateEthyl 3-hydroxybutyrate (natural)(R)-Ethyl 3-hydroxybutyrateEINECS 226-456-2

Open full PubChem record PubChem annotations 3D structure image

External database identifiers

ChEBI:CHEBI:87685
EPA DTXSID:DTXSID6025305
PubMed:21412860
PubMed:20838519
PubMed:19326950
PubMed:19093461
PubMed:18853207
PubMed:18354808
PubMed:18201766
PubMed:17880742
PubMed:17355145
PubMed:17191902
PubMed:16839161
PubMed:16233006

Retrieved from NIH PubChem on 2026-08-31 by checksum-valid CAS matching. Chemical properties do not replace the regulatory decision on this page.

Inventory details for ETHYL 3-HYDROXYBUTYRATE

INCI name

ETHYL 3-HYDROXYBUTYRATE

Description

Ethyl 3-hydroxybutyrate

Record provenance

Inventory reference: 39873
Imported identity: ETHYL 3-HYDROXYBUTYRATE
Source update: 02/03/2011

European Commission CosIng source notes

Annex records for ETHYL 3-HYDROXYBUTYRATE

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Key data

CAS

5405-41-4

226-456-2

Restriction

—

Function

PERFUMING: Used for perfume and aromatic raw materials.

Ingredients with overlapping formulation functions

ETHYL 2-METHYLVALERATEPERFUMING

ETHYL 2-OCTENOATEPERFUMING

ETHYL 3,5,5-TRIMETHYLHEXANOATEPERFUMING

ETHYL 3-HYDROXY-3-PHENYLPROPIONATEPERFUMING

ETHYL 3-HYDROXYHEXANOATEPERFUMING

ETHYL 3-PHENYLGLYCIDATEPERFUMING

ETHYL 5,5,7-TRIMETHYL-1-OXASPIROOCTANE-2-CARBOXYLATEPERFUMING

ETHYL ACETATEPERFUMING, SOLVENT

Additional official and scientific sources

11 external databases to check this identity in

Each link searches that source for this identity. What each source is, and its legal weight

ECHA CHEM / Information on chemicals PubChem PUG REST EU Safety Gate cosmetic product alerts ECHA CHEM US EPA CompTox Cosmetic Ingredient Review safety assessments FDA Global Substance Registration System ILO/WHO International Chemical Safety Cards Japan NITE-CHRIP NIOSH Pocket Guide to Chemical Hazards OECD eChemPortal

How ETHYL 3-HYDROXYBUTYRATE appears in the CosIng inventory

The CosIng inventory lists ETHYL 3-HYDROXYBUTYRATE as a cosmetic ingredient and this page links it to 0 annex records. The inventory entry captures names and identifiers, while the annex records show where the substance is prohibited, restricted or positively listed in EU cosmetics law.

ETHYL 3-HYDROXYBUTYRATE is also tagged with 1 cosmetic function in the official data. Function labels describe intended use, but they do not replace regulatory review of linked annex records before formulation or labelling work.

Frequently asked questions

ETHYL 3-HYDROXYBUTYRATE is listed in the EU CosIng ingredient inventory with no direct annex restriction records linked at this time. Absence of an annex link does not guarantee unrestricted use — always verify against the current official CosIng database before formulating.

According to the EU CosIng inventory, ETHYL 3-HYDROXYBUTYRATE carries the following function designation(s):

PERFUMING

CAS 5405-41-4 may appear across multiple EU annex records. Viewing the CAS lookup page shows all Annex II–VI entries sharing this identifier, which is useful for identifying cross-annex regulatory status of the same chemical substance.

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Source note for ETHYL 3-HYDROXYBUTYRATE

This page reproduces the CosIng inventory entry for ETHYL 3-HYDROXYBUTYRATE from public European Commission cosmetic ingredient materials and shows linked identifiers even when no direct annex match is currently attached.

Use this inventory page to research ETHYL 3-HYDROXYBUTYRATE and compare linked records, but verify restrictions and legal status against the current official source text and law before making regulatory decisions.

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