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InventoryRef 3986902/03/2011

ETHYLHEXANOL

2-Ethylhexan-1-ol

ETHYLHEXANOL is listed in the EU CosIng inventory, but no direct annex records are linked on this page yet.

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Regulatory evidence by market

No rule for this ingredient has been imported for any of the 13 markets tracked here.

That describes this inventory, not the law. No imported rule is not evidence that an ingredient is permitted: a rule may exist under another name or identifier, or in a dataset not yet imported here.

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Chemical identity and properties

PubChem 2D chemical structure for CAS 104-76-7
CAS 104-76-7PubChem CID 7720

2-Ethylhexanol

2-ethylhexan-1-ol is a primary alcohol that is hexan-1-ol substituted by an ethyl group at position 2. It has a role as a volatile oil component and a plant metabolite. — ChEBI

IUPAC name
2-ethylhexan-1-ol
Molecular formula
C8H18O
Molecular weight
130.23 g/mol
Exact mass
130.135765193 Da
XLogP3
3.1
Topological polar surface area
20.2 Ų
Hydrogen-bond donors
1
Hydrogen-bond acceptors
1
Covalent units
1
Defined stereocentres
0

Also known as

2-ETHYL-1-HEXANOL2-Ethylhexyl alcohol1-Hexanol, 2-ethyl-Ethylhexanol2-ETHYL HEXANOL2-AethylhexanolAlcohol, 2-ethylhexylFEMA No. 3151
16 more reported names
XZV7TAA77PNSC-9300CHEBI:16011RefChem:471944203-234-3xi-2-Ethyl-1-hexanolDocusate Sodium Impurity 12-Aethylhexanol [German]2-Ethyl-hexan-1-olEthylhexanol, 2-CAS-104-76-72-ethyl 1-hexanolCCRIS 2292HSDB 1118NSC 9300EINECS 203-234-3
Open full PubChem recordPubChem annotations3D structure image
External database identifiers

Evidence from additional scientific databases

EMBL-EBI ChEBI
Exact identifier matchCHEBI:16011

2-ethylhexan-1-ol

A primary alcohol that is hexan-1-ol substituted by an ethyl group at position 2.

Formula
C8H18O
Average mass
130.231 g/mol
Monoisotopic mass
130.13577 Da
Formal charge
0
  • primary alcohol — is a (CHEBI:15734)
  • volatile oil component — has role (CHEBI:27311)
  • plant metabolite — has role (CHEBI:76924)
  • volatile oil component — has role (CHEBI:27311)
  • plant metabolite — has role (CHEBI:76924)
  • primary alcohol — is a (CHEBI:15734)
Additional curated names
2-ethylhexan-1-ol2-ethyl-1-hexanol2-Ethyl-1-hexanol2-Ethylhexan-1-ol
Cross-references from this source
  • CAS: 104-76-7 — KEGG COMPOUND
  • REGISTRY_NUMBER: 1719280 — Reaxys
  • MANUAL_X_REF: 2-Ethylhexanol — Wikipedia
  • MANUAL_X_REF: C02498 — KEGG COMPOUND
  • MANUAL_X_REF: C02498 — KEGG COMPOUND
  • MANUAL_X_REF: HMDB0031231 — HMDB

Mapped by: Exact CAS cross-reference in the ChEBI compound record. Source updated: 2017-11-13. Retrieved: 2026-08-31. Open source record

NIH PubChem PUG-View
Exact identifier match7720

Attributed physical-property, hazard, environmental and use annotations.

  • First Aid: EYES: First check the victim for contact lenses and remove if present. Flush victim's eyes with water or normal saline solution for 20 to 30 minutes while simultaneously calling a hospital or poison control center. Do not put any ointments, oils, or medication in the victim's eyes without specific instructions from a physician. IMMEDIATELY transport the victim after flushing eyes to a hospital even if no symptoms (such as redness or irritation) develop.; SKIN: IMMEDIATELY flood affected skin with water while removing and isolating all contaminated clothing. Gently wash all affected skin areas thoroughly with soap and water. If symptoms such as redness or irritation develop, IMMEDIATELY call a physician and be prepared to transport the victim to a hospital for treatment.; INHALATION: IMMEDIATELY leave the contaminated area; take deep breaths of fresh air. If symptoms (such as wheezing, coughing, shortness of breath, or burning in the mouth, throat, or chest) develop, call a physician and be prepared to transport the victim to a hospital. Provide proper respiratory protection to rescuers entering an unknown atmosphere. Whenever possible, Self-Contained Breathing Apparatus (SCBA) shou Source: CAMEO Chemicals
  • Note: This chemical does not meet GHS hazard criteria for 0.7% (26 of 3744) of reports. Source: European Chemicals Agency (ECHA)
  • Signal: Warning Source: European Chemicals Agency (ECHA)
  • GHS Hazard Statements: H315 (88.6%): Causes skin irritation [Warning Skin corrosion/irritation]; H319 (98.7%): Causes serious eye irritation [Warning Serious eye damage/eye irritation]; H332 (71.2%): Harmful if inhaled [Warning Acute toxicity, inhalation]; H335 (72.5%): May cause respiratory irritation [Warning Specific target organ toxicity, single exposure; Respiratory tract irritation] Source: European Chemicals Agency (ECHA)
  • Precautionary Statement Codes: P261, P264, P264+P265, P271, P280, P302+P352, P304+P340, P305+P351+P338, P317, P319, P321, P332+P317, P337+P317, P362+P364, P403+P233, P405, and P501 (click each P-code to see the statement) Source: European Chemicals Agency (ECHA)
  • ECHA C&L Notifications Summary: Aggregated GHS information provided per 3744 reports by companies from 58 notifications to the ECHA C&L Inventory. Each notification may be associated with multiple companies.; Reported as not meeting GHS hazard criteria per 26 of 3744 reports by companies.; There are 57 notifications provided by 3718 of 3744 reports by companies with hazard statement code(s).; Information may vary between notifications depending on impurities, additives, and other factors. The percentage value in parenthesis indicates the notified classification ratio from companies that provide hazard codes. Only hazard codes with percentage values above 10% are shown. For more detailed information, please visit ECHA C&L website. Source: European Chemicals Agency (ECHA)
  • GHS Hazard Statements: H402: Harmful to aquatic life [Hazardous to the aquatic environment, acute hazard] Source: NITE-CMC
  • Precautionary Statement Codes: P273, and P501 (click each P-code to see the statement) Source: NITE-CMC
  • Signal: Warning Source: NITE-CMC
  • GHS Hazard Statements: H227: Combustible liquid [Warning Flammable liquids]; H315: Causes skin irritation [Warning Skin corrosion/irritation]; H319: Causes serious eye irritation [Warning Serious eye damage/eye irritation]; H336: May cause drowsiness or dizziness [Warning Specific target organ toxicity, single exposure; Narcotic effects]; H361: Suspected of damaging fertility or the unborn child [Warning Reproductive toxicity]; H371: May cause damage to organs [Warning Specific target organ toxicity, single exposure]; H401: Toxic to aquatic life [Hazardous to the aquatic environment, acute hazard] Source: NITE-CMC
  • Precautionary Statement Codes: P203, P210, P260, P261, P264, P264+P265, P270, P271, P273, P280, P302+P352, P304+P340, P305+P351+P338, P308+P316, P318, P319, P321, P332+P317, P337+P317, P362+P364, P370+P378, P403, P403+P233, P405, and P501 (click each P-code to see the statement) Source: NITE-CMC
  • GHS Hazard Statements: H227: Combustible liquid [Warning Flammable liquids]; H312: Harmful in contact with skin [Warning Acute toxicity, dermal]; H315: Causes skin irritation [Warning Skin corrosion/irritation]; H319: Causes serious eye irritation [Warning Serious eye damage/eye irritation]; H335: May cause respiratory irritation [Warning Specific target organ toxicity, single exposure; Respiratory tract irritation]; H336: May cause drowsiness or dizziness [Warning Specific target organ toxicity, single exposure; Narcotic effects]; H361: Suspected of damaging fertility or the unborn child [Warning Reproductive toxicity] Source: NITE-CMC
  • Precautionary Statement Codes: P203, P210, P261, P264, P264+P265, P271, P280, P302+P352, P304+P340, P305+P351+P338, P317, P318, P319, P321, P332+P317, P337+P317, P362+P364, P370+P378, P403, P403+P233, P405, and P501 (click each P-code to see the statement) Source: NITE-CMC
  • NFPA Health Rating: 2 - Materials that, under emergency conditions, can cause temporary incapacitation or residual injury. Source: Hazardous Substances Data Bank (HSDB)
  • NFPA Fire Rating: 2 - Materials that must be moderately heated or exposed to relatively high ambient temperatures before ignition can occur. Materials would not under normal conditions form hazardous atmospheres with air, but under high ambient temperatures or under moderate heating could release vapor in sufficient quantities to produce hazardous atmospheres with air. Source: Hazardous Substances Data Bank (HSDB)
  • NFPA Instability Rating: 0 - Materials that in themselves are normally stable, even under fire conditions. Source: Hazardous Substances Data Bank (HSDB)
  • Environmental Bioconcentration: An estimated BCF of 30 was calculated in fish for 2-ethylhexanol(SRC), using an estimated log Kow of 2.73(1) and a regression-derived equation(1). According to a classification scheme(2), this BCF suggests the potential for bioconcentration in aquatic organisms is low(SRC). Source: Hazardous Substances Data Bank (HSDB)
  • Environmental Fate: TERRESTRIAL FATE: Based on a classification scheme(1), an estimated Koc value of 35(SRC), determined from a structure estimation method(2), indicates that 2-ethylhexanol is expected to have very high mobility in soil(SRC). Volatilization of 2-ethylhexanol from moist soil surfaces is expected to be an important fate process(SRC) given an estimated Henry's Law constant of 2.6X10-5 atm-cu m/mole(SRC), based upon its vapor pressure, 0.136 mm Hg(3), and water solubility, 880 mg/L(4). 2-Ethylhexanol is not expected to volatilize from dry soil surfaces(SRC) based upon its vapor pressure(3). Based on 31, 52, and 5% biodegradation when incubated for 21 days in soil from a waste disposal site, in soil amended with nitrogen, and in soil incubated under anaerobic conditions, respectively(5), biodegradation may be an important environmental fate process in soil(SRC). Source: Hazardous Substances Data Bank (HSDB)
  • Environmental Fate: AQUATIC FATE: Based on a classification scheme(1), an estimated Koc value of 35(SRC), determined from a structure estimation method(2), indicates that 2-ethylhexanol is not expected to adsorb to suspended solids and sediment(SRC). Volatilization from water surfaces is expected(3) based upon an estimated Henry's Law constant of 2.6X10-5 atm-cu m/mole(SRC), derived from its vapor pressure, 0.136 mm Hg(4), and water solubility, 880 mg/L(5). Using this Henry's Law constant and an estimation method(3), volatilization half-lives for a model river and model lake are 41 hours and 16 days, respectively(SRC). According to a classification scheme(6), an estimated BCF of 30(SRC), from an estimated log Kow of 2.73(2) and a regression-derived equation(2), suggests the potential for bioconcentration in aquatic organisms is low(SRC). Using river water incubated at 18-19 °C, 59% biodegradation after 9 days(11) suggests that biodegradation may be an important enviornmental fate process in water(SRC). Source: Hazardous Substances Data Bank (HSDB)
  • Environmental Fate: ATMOSPHERIC FATE: According to a model of gas/particle partitioning of semivolatile organic compounds in the atmosphere(1), 2-ethylhexanol, which has a vapor pressure of 0.136 mm Hg at 25 °C(2), is expected to exist solely as a vapor in the ambient atmosphere. Vapor-phase 2-ethylhexanol is degraded in the atmosphere by reaction with photochemically-produced hydroxyl radicals(SRC); the half-life for this reaction in air is estimated to be 26 hours(SRC), calculated from its rate constant of 1.3X10-11 cu cm/molecule-sec at 25 °C(SRC) that was derived using a structure estimation method(3). 2-Ethylhexanol does not contain chromophores that absorb at wavelengths >290 nm(4) and, therefore, is not expected to be susceptible to direct photolysis by sunlight(SRC). Source: Hazardous Substances Data Bank (HSDB)
  • Consumer Uses: Fuel; Monomers; Chain transfer agent; Solvent; Dispersing agent; Dye; Adhesion/cohesion promoter; Intermediate; Emulsifier; Not Known or Reasonably Ascertainable; Plasticizer Source: EPA Chemical Data Reporting (CDR)
  • Industry Uses: Processing aids not otherwise specified; Monomers; Surfactant (surface active agent); Fuel agents; Fuel; Solvent; Dispersing agent; CBI; Chain transfer agent; Adhesion/cohesion promoter; Intermediate; Dye; Plasticizer; Cleaning agent; Filler; Not Known or Reasonably Ascertainable; Corrosion inhibitor; Emulsifier Source: EPA Chemical Data Reporting (CDR)
  • Sources/Uses: Used as a plasticizer, defoaming agent, wetting agent, solvent (nitrocellulose, paints, lacquers, and baking finishes), and textile finishing compound; Also used in inks, rubber, paper, lubricants, photography, and dry cleaning; [Hawley] Source: Haz-Map, Information on Hazardous Chemicals and Occupational Diseases
  • Industrial Processes with risk of exposure: Pulp and Paper Processing [Category: Industry]; Painting (Solvents) [Category: Paint]; Dry Cleaning [Category: Clean]; Photographic Processing [Category: Other]; Textiles (Printing, Dyeing, or Finishing) [Category: Industry] Source: Haz-Map, Information on Hazardous Chemicals and Occupational Diseases
  • Uses: USE A sensitive method for the extraction and determination of polycyclic aromatic hydrocarbons (PAHs) using alcoholic-assisted dispersive liquid-liquid microextraction (AA-DLLME) and HPLC was developed... The effective parameters (type and volume of extraction and dispersive solvents, amount of salt and stirring time) on the extraction recovery were studied and optimized utilizing factorial design (FD) and central composite design (CCD). The best recovery was achieved by FD using 2-ethyl-1-hexanol as the extraction solvent and methanol as the dispersive solvent... The optimized conditions were 145 uL of 2-ethyl-1-hexanol as the extraction solvent and 4.2% w/v of salt (NaCl) in sample solution... Source: Hazardous Substances Data Bank (HSDB)
  • Uses: For 2-ethyl-1-hexanol (USEPA/OPP Pesticide Code: 079098) there are 0 labels match. /SRP: Not registered for current use in the U.S., but approved pesticide uses may change periodically and so federal, state and local authorities must be consulted for currently approved uses./ Source: Hazardous Substances Data Bank (HSDB)
  • Uses: 2-Ethylhexanol is mainly used as the alcohol component for the manufacture of ester plasticizers for soft poly(vinyl chloride) (PVC). Source: Hazardous Substances Data Bank (HSDB)
  • Uses: Mercerizing textiles; as solvent for dyes, resins, oils; also claimed to possess antifoaming properties. Source: Hazardous Substances Data Bank (HSDB)
  • Uses: Plasticizer for PVC resins; wetting agent; organic synthesis; solvent mixtures for nitrocellulose, paints, lacquers, baking finishes ... Inks; rubber; paper; lubricants; photography; dry cleaning Source: Hazardous Substances Data Bank (HSDB)

Mapped by: Existing checksum-valid CAS to unique PubChem CID match. Retrieved: 2026-08-31. Open source record

Scientific classifications and hazard annotations provide context and do not replace the market-specific regulatory decision shown above.

Additional source coverage and match status
SourceResultChecked
EMBL-EBI ChEBIExact match2026-08-31
NIH PubChem PUG-ViewExact match2026-08-31

A recorded no-match is useful evidence that the source was checked; it is not a claim that the substance does not exist elsewhere.

Retrieved from NIH PubChem on 2026-09-02 by checksum-valid CAS matching. Chemical properties do not replace the regulatory decision on this page.

Inventory details for ETHYLHEXANOL

INCI name

ETHYLHEXANOL

Description

2-Ethylhexan-1-ol

Record provenance

Inventory reference
39869
Imported identity
ETHYLHEXANOL
Source update
02/03/2011
European Commission CosIng source notes
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Key data

CAS
104-76-7
EC
203-234-3
Restriction
—
Function
PERFUMING
Used for perfume and aromatic raw materials.

Records sharing a CAS or EC identity

2-ETHYLHEXANOL

Ingredients with overlapping formulation functions

ETHYLBENZENEPERFUMING
ETHYLCYCLOHEXENE-1-CARBOXYLATEPERFUMING
ETHYLENE DODECANEDIOATEFRAGRANCE, PERFUMING
ETHYLHEXANALPERFUMING
ETHYLHEXYL ACETATEPERFUMING, SOLVENT
ETHYLHEXYL ISOBUTYRATEPERFUMING
ETHYLHEXYL PALMITATEPERFUMING, SKIN CONDITIONING - EMOLLIENT
ETHYLPENTYLOXYACETIC ACIDPERFUMING

Additional official and scientific sources

11 external databases to check this identity in

Each link searches that source for this identity. What each source is, and its legal weight

ECHA CHEM / Information on chemicalsPubChem PUG RESTEU Safety Gate cosmetic product alertsECHA CHEMUS EPA CompToxCosmetic Ingredient Review safety assessmentsFDA Global Substance Registration SystemILO/WHO International Chemical Safety CardsJapan NITE-CHRIPNIOSH Pocket Guide to Chemical HazardsOECD eChemPortal

How ETHYLHEXANOL appears in the CosIng inventory

The CosIng inventory lists ETHYLHEXANOL as a cosmetic ingredient and this page links it to 0 annex records. The inventory entry captures names and identifiers, while the annex records show where the substance is prohibited, restricted or positively listed in EU cosmetics law.

ETHYLHEXANOL is also tagged with 1 cosmetic function in the official data. Function labels describe intended use, but they do not replace regulatory review of linked annex records before formulation or labelling work.

Frequently asked questions

ETHYLHEXANOL is listed in the EU CosIng ingredient inventory with no direct annex restriction records linked at this time. Absence of an annex link does not guarantee unrestricted use — always verify against the current official CosIng database before formulating.

According to the EU CosIng inventory, ETHYLHEXANOL carries the following function designation(s):

CAS 104-76-7 may appear across multiple EU annex records. Viewing the CAS lookup page shows all Annex II–VI entries sharing this identifier, which is useful for identifying cross-annex regulatory status of the same chemical substance.
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Source note for ETHYLHEXANOL

This page reproduces the CosIng inventory entry for ETHYLHEXANOL from public European Commission cosmetic ingredient materials and shows linked identifiers even when no direct annex match is currently attached.

Use this inventory page to research ETHYLHEXANOL and compare linked records, but verify restrictions and legal status against the current official source text and law before making regulatory decisions.

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