InventoryRef 3960002/03/2011
DIMETHYLBUTYL ACETATE
1,3-Dimethylbutyl acetate
DIMETHYLBUTYL ACETATE is listed in the EU CosIng inventory, but no direct annex records are linked on this page yet.
Regulatory evidence by market
No rule for this ingredient has been imported for any of the 13 markets tracked here.
That describes this inventory, not the law. No imported rule is not evidence that an ingredient is permitted: a rule may exist under another name or identifier, or in a dataset not yet imported here.
Chemical identity and properties
CAS 108-84-9PubChem CID 7959
4-Methyl-2-pentyl acetate
Methylamyl acetate appears as a clear colorless liquid. Flash point 95 °F. Less dense than water and insoluble in water. Vapors heavier than air. — CAMEO Chemicals
- IUPAC name
- 4-methylpentan-2-yl acetate
- Molecular formula
- C8H16O2
- Molecular weight
- 144.21 g/mol
- Exact mass
- 144.115029749 Da
- XLogP3
- 2.2
- Topological polar surface area
- 26.3 Ų
- Hydrogen-bond donors
- 0
- Hydrogen-bond acceptors
- 2
- Covalent units
- 1
- Defined stereocentres
- 0
Also known as
1,3-Dimethylbutyl acetateMethylamyl acetateMethylisoamyl acetate4-Methyl-2-amyl acetatesec-Hexyl acetate1,3-Dimethylbutyl ethanoateMethyl amyl acetateMethylisobutylcarbinol acetate
16 more reported names
Methylisobutylcarbinyl acetate2-Pentanol, 4-methyl-, acetate4-Methyl-2-pentanol, acetateNSC 5674-Methyl-2-pentanol acetateAcetic acid, 1,3-dimethylbutyl esterHSDB 1155IP9ZB28RWN2-Pentanol, 4-methyl-, 2-acetateEINECS 203-621-7Acetic Acid 1,3-Dimethylbutyl EsterUN12331,3-Dimethylbutylester kyseliny octoveBRN 1749848sek.Isohexylester kyseliny octove [Czech]sek.Isohexylester kyseliny octove
External database identifiers
- EPA DTXSID:DTXSID6051562
- PubMed:20232333
Evidence from additional scientific databases
NIH PubChem PUG-View
Exact identifier match7959
Attributed physical-property, hazard, environmental and use annotations.
- Autoignition Temperature: 510 °F (USCG, 1999) Source: CAMEO Chemicals
- Autoignition Temperature: 510 °F (CALCULATED) Source: Hazardous Substances Data Bank (HSDB)
- Boiling Point: 295.2 °F at 760 mmHg (USCG, 1999) Source: CAMEO Chemicals
- Boiling Point: 147.5 °C Source: Hazardous Substances Data Bank (HSDB)
- Boiling Point: HEXYL ACETATE EXISTS IN FORM OF SEVERAL ISOMERS WITH BOILING POINTS RANGING FROM 146-156 °C Source: Hazardous Substances Data Bank (HSDB)
- Boiling Point: 146 °C Source: ILO-WHO International Chemical Safety Cards (ICSCs)
- Boiling Point: 297 °F Source: Occupational Safety and Health Administration (OSHA)
- Boiling Point: 297 °F Source: The National Institute for Occupational Safety and Health (NIOSH)
- Color/Form: Colorless liquid. Source: Hazardous Substances Data Bank (HSDB)
- Density: 0.86 at 68 °F (USCG, 1999) - Less dense than water; will float Source: CAMEO Chemicals
- Density: 0.8805 g/cu cm at 25 °C Source: Hazardous Substances Data Bank (HSDB)
- Density: Bulk density = 7.1 lb/gal Source: Hazardous Substances Data Bank (HSDB)
- Density: Relative density (water = 1): 0.86 Source: ILO-WHO International Chemical Safety Cards (ICSCs)
- Density: 0.86 Source: Occupational Safety and Health Administration (OSHA)
- Density: 0.86 Source: The National Institute for Occupational Safety and Health (NIOSH)
- Flash Point: 113 °F (USCG, 1999) Source: CAMEO Chemicals
- Flash Point: 45 °C Source: Haz-Map, Information on Hazardous Chemicals and Occupational Diseases
- Flash Point: 110 °F (Open cup) Source: Hazardous Substances Data Bank (HSDB)
- Flash Point: 113 °F; 45 °C (Closed cup) Source: Hazardous Substances Data Bank (HSDB)
- Flash Point: 45 °C c.c. Source: ILO-WHO International Chemical Safety Cards (ICSCs)
- Flash Point: 113 °F Source: Occupational Safety and Health Administration (OSHA)
- Flash Point: 113 °F Source: The National Institute for Occupational Safety and Health (NIOSH)
- Melting Point: -82.8 °F (USCG, 1999) Source: CAMEO Chemicals
- Melting Point: Freezing point = -63.8 °C Source: Hazardous Substances Data Bank (HSDB)
- Melting Point: -64 °C Source: ILO-WHO International Chemical Safety Cards (ICSCs)
- Melting Point: -83 °F Source: Occupational Safety and Health Administration (OSHA)
- Melting Point: -83 °F Source: The National Institute for Occupational Safety and Health (NIOSH)
- Odor: Mild, pleasant, fruity odor. Source: Hazardous Substances Data Bank (HSDB)
- Physical Description: Methylamyl acetate appears as a clear colorless liquid. Flash point 95 °F. Less dense than water and insoluble in water. Vapors heavier than air. Source: CAMEO Chemicals
- Physical Description: Colorless liquid with a mild, pleasant, fruity odor; [NIOSH] Source: Haz-Map, Information on Hazardous Chemicals and Occupational Diseases
- Physical Description: COLOURLESS LIQUID WITH CHARACTERISTIC ODOUR. Source: ILO-WHO International Chemical Safety Cards (ICSCs)
- Physical Description: Colorless liquid with a mild, pleasant, fruity odor. Source: Occupational Safety and Health Administration (OSHA)
- Physical Description: Colorless liquid with a mild, pleasant, fruity odor. Source: The National Institute for Occupational Safety and Health (NIOSH)
- Refractive Index: INDEX OF REFRACTION: 1.3980 @ 20 °C/D Source: Hazardous Substances Data Bank (HSDB)
- Refractive Index: Index of refraction = 1.4012 at 20 °C Source: Hazardous Substances Data Bank (HSDB)
- Solubility: 0.08 % (NIOSH, 2024) Source: CAMEO Chemicals
- Solubility: Very soluble in ethyl ether and ethanol. Source: Hazardous Substances Data Bank (HSDB)
- Solubility: 0.08 G/100 ML WATER Source: Hazardous Substances Data Bank (HSDB)
- Solubility: 0.13%WT in aq, 20 °C; 0.57%w aq in, 20 °C Source: Hazardous Substances Data Bank (HSDB)
- Solubility: Miscible with alcohol Source: Hazardous Substances Data Bank (HSDB)
- Solubility: Solubility in water: none Source: ILO-WHO International Chemical Safety Cards (ICSCs)
- Solubility: 0.08% Source: The National Institute for Occupational Safety and Health (NIOSH)
- Vapor Pressure: 10.86 mmHg (USCG, 1999) Source: CAMEO Chemicals
- Vapor Pressure: 4.0 [mmHg] Source: Haz-Map, Information on Hazardous Chemicals and Occupational Diseases
- Vapor Pressure: 4 mm Hg at 20 °C Source: Hazardous Substances Data Bank (HSDB)
- Vapor Pressure: Vapor pressure, kPa at 20 °C: 0.4 Source: ILO-WHO International Chemical Safety Cards (ICSCs)
- Vapor Pressure: 3 mmHg Source: Occupational Safety and Health Administration (OSHA)
- Vapor Pressure: 3 mmHg Source: The National Institute for Occupational Safety and Health (NIOSH)
- Viscosity: Viscosity coefficient = 0.93 cP at 20 °C Source: Hazardous Substances Data Bank (HSDB)
- Exposure Routes: The substance can be absorbed into the body by inhalation of its vapour. Source: ILO-WHO International Chemical Safety Cards (ICSCs)
- Exposure Routes: inhalation, ingestion, skin and/or eye contact Source: The National Institute for Occupational Safety and Health (NIOSH)
- First Aid: Excerpt from NIOSH Pocket Guide for sec-Hexyl acetate:; Eye: IRRIGATE IMMEDIATELY - If this chemical contacts the eyes, immediately wash (irrigate) the eyes with large amounts of water, occasionally lifting the lower and upper lids. Get medical attention immediately.; Skin: WATER FLUSH PROMPTLY - If this chemical contacts the skin, flush the contaminated skin with water promptly. If this chemical penetrates the clothing, immediately remove the clothing and flush the skin with water promptly. If irritation persists after washing, get medical attention.; Breathing: RESPIRATORY SUPPORT - If a person breathes large amounts of this chemical, move the exposed person to fresh air at once. If breathing has stopped, perform artificial respiration. Keep the affected person warm and at rest. Get medical attention as soon as possible.; Swallow: MEDICAL ATTENTION IMMEDIATELY - If this chemical has been swallowed, get medical attention immediately. (NIOSH, 2024) Source: CAMEO Chemicals
- ERG2024, Guide 130 (Methylamyl acetate): General First Aid:; · Call 911 or emergency medical service.; · Ensure that medical personnel are aware of the material(s) involved, take precautions to protect themselves and avoid contamination.; · Move victim to fresh air if it can be done safely.; · Administer oxygen if breathing is difficult.; · If victim is not breathing:; -- DO NOT perform mouth-to-mouth resuscitation; the victim may have ingested or inhaled the substance.; -- If equipped and pulse detected, wash face and mouth, then give artificial respiration using a proper respiratory medical device (bag-valve mask, pocket mask equipped with a one-way valve or other device).; -- If no pulse detected or no respiratory medical device available, provide continuous compressions. Conduct a pulse check every two minutes or monitor for any signs of spontaneous respirations.; · Remove and isolate contaminated clothing and shoes.; · For minor skin contact, avoid spreading material on unaffected skin.; · In case of contact with substance, remove immediately by flushing skin or eyes with running water for at least 20 minutes.; · For severe burns, immediate medical attention is required.; · Effects of exposure (inhalation, ingestion, Source: Emergency Response Guidebook (ERG)
- First Aid: (General first aid procedures); Eye: Irrigate immediately - If this chemical contacts the eyes, immediately wash (irrigate) the eyes with large amounts of water, occasionally lifting the lower and upper lids. Get medical attention immediately.; Skin: Water flush promptly - If this chemical contacts the skin, flush the contaminated skin with water promptly. If this chemical penetrates the clothing, immediately remove the clothing and flush the skin with water promptly. If irritation persists after washing, get medical attention.; Breathing: Respiratory support; Swallow: Medical attention immediately - If this chemical has been swallowed, get medical attention immediately. Source: The National Institute for Occupational Safety and Health (NIOSH)
- Signal: Warning Source: European Chemicals Agency (ECHA)
- GHS Hazard Statements: H226 (100%): Flammable liquid and vapor [Warning Flammable liquids]; H315 (30.5%): Causes skin irritation [Warning Skin corrosion/irritation]; H319 (30.5%): Causes serious eye irritation [Warning Serious eye damage/eye irritation]; H335 (29.7%): May cause respiratory irritation [Warning Specific target organ toxicity, single exposure; Respiratory tract irritation] Source: European Chemicals Agency (ECHA)
- Precautionary Statement Codes: P210, P233, P240, P241, P242, P243, P261, P264, P264+P265, P271, P280, P302+P352, P303+P361+P353, P304+P340, P305+P351+P338, P319, P321, P332+P317, P337+P317, P362+P364, P370+P378, P403+P233, P403+P235, P405, and P501 (click each P-code to see the statement) Source: European Chemicals Agency (ECHA)
- ECHA C&L Notifications Summary: Aggregated GHS information provided per 128 reports by companies from 3 notifications to the ECHA C&L Inventory. Each notification may be associated with multiple companies.; Information may vary between notifications depending on impurities, additives, and other factors. The percentage value in parenthesis indicates the notified classification ratio from companies that provide hazard codes. Only hazard codes with percentage values above 10% are shown. For more detailed information, please visit ECHA C&L website. Source: European Chemicals Agency (ECHA)
- Signal: Warning Source: NITE-CMC
- GHS Hazard Statements: H226: Flammable liquid and vapor [Warning Flammable liquids]; H315: Causes skin irritation [Warning Skin corrosion/irritation]; H319: Causes serious eye irritation [Warning Serious eye damage/eye irritation]; H335: May cause respiratory irritation [Warning Specific target organ toxicity, single exposure; Respiratory tract irritation]; H336: May cause drowsiness or dizziness [Warning Specific target organ toxicity, single exposure; Narcotic effects] Source: NITE-CMC
- Precautionary Statement Codes: P210, P233, P240, P241, P242, P243, P261, P264, P264+P265, P271, P280, P302+P352, P303+P361+P353, P304+P340, P305+P351+P338, P319, P321, P332+P317, P337+P317, P362+P364, P370+P378, P403+P233, P403+P235, P405, and P501 (click each P-code to see the statement) Source: NITE-CMC
- GHS Hazard Statements: H226: Flammable liquid and vapor [Warning Flammable liquids]; H315: Causes skin irritation [Warning Skin corrosion/irritation]; H320: Causes eye irritation [Warning Serious eye damage/eye irritation]; H335: May cause respiratory irritation [Warning Specific target organ toxicity, single exposure; Respiratory tract irritation]; H336: May cause drowsiness or dizziness [Warning Specific target organ toxicity, single exposure; Narcotic effects] Source: NITE-CMC
- NFPA Health Rating: 0 - Materials that, under emergency conditions, would offer no hazard beyond that of ordinary combustible materials. Source: Hazardous Substances Data Bank (HSDB)
- NFPA Fire Rating: 2 - Materials that must be moderately heated or exposed to relatively high ambient temperatures before ignition can occur. Materials would not under normal conditions form hazardous atmospheres with air, but under high ambient temperatures or under moderate heating could release vapor in sufficient quantities to produce hazardous atmospheres with air. Source: Hazardous Substances Data Bank (HSDB)
- NFPA Instability Rating: 0 - Materials that in themselves are normally stable, even under fire conditions. Source: Hazardous Substances Data Bank (HSDB)
- Target Organs: Eyes, skin, respiratory system, central nervous system Source: The National Institute for Occupational Safety and Health (NIOSH)
- Environmental Bioconcentration: An estimated BCF of 66 was calculated for 4-methyl-2-pentyl acetate(SRC), using an estimated log Kow of 2.7(1,SRC) and a recommended regression-derived equation(2). According to a classification scheme(3), this BCF suggests that bioconcentration in aquatic organisms is moderate, not high(SRC). Source: Hazardous Substances Data Bank (HSDB)
- Environmental Fate: TERRESTRIAL FATE: Based on a recommended classification scheme(1), an estimated Koc value of 700(SRC), determined from an estimated log Kow of 2.7(2,SRC) and a recommended regression-derived equation(3), indicates that 4-methyl-2-pentyl acetate is expected to have low mobility in soil(SRC). Volatilization of 4-methyl-2-pentyl acetate from moist soil surfaces is expected to be important(SRC) given an estimated Henry's Law constant of 5.8X10-4 atm-cu m/mole at 20 °C(SRC) from its experimental values for vapor pressure, 4.0 mm Hg(4), and water solubility, 1.3X10+3 mg/l(4). The potential for volatilization of 4-methyl-2-pentyl acetate from dry soil surfaces may exist(SRC) based upon its measured vapor pressure(4). Volatilization is expected to be attenuated by adsorption(SRC). Biodegradation of 4-methyl-2-pentyl acetate in soil may be important(SRC), based upon its biodegradation in aerobic screening tests(5). Source: Hazardous Substances Data Bank (HSDB)
- Environmental Fate: AQUATIC FATE: Based on a recommended classification scheme(1), an estimated Koc value of 700(SRC), determined from an estimated log Kow of 2.7(2,SRC) and a recommended regression-derived equation(3), indicates that 4-methyl-2-pentyl acetate is expected to adsorb to suspended solids and sediment in water(SRC). 4-Methyl-2-pentyl acetate is expected to volatilize from water surfaces(3,SRC) based on an estimated Henry's Law constant of 5.8X10-4 atm-cu m/mole at 20 °C(SRC) from its experimental values for vapor pressure, 4.0 mm Hg(4), and water solubility, 1.3X10+3 mg/l(4). Estimated volatilization half-lives for a model river and model lake are 5.3 hours and 5.3 days, respectively(3,SRC). Adsorption is expected to attenuate volatilization(SRC). According to a classification scheme(5), an estimated BCF of 66(3,SRC), from an estimated log Kow(2,SRC), suggests that bioconcentration in aquatic organisms is moderate, not high(SRC). 4-Methyl-2-pentyl acetate is expected to biodegrade in aquatic systems(SRC). In aerobic screening tests using an unacclimated sewage seed, 4-methyl-2-pentyl acetate reached 20, 87, 62 and 69% of its theoretical BOD in freshwater and 11, 22, 52, and 67% of its the Source: Hazardous Substances Data Bank (HSDB)
- Environmental Fate: ATMOSPHERIC FATE: According to a model of gas/particle partitioning of semivolatile organic compounds in the atmosphere(1), 4-methyl-2-pentyl acetate, which has a measured vapor pressure of 4 mm Hg at 20 °C(2), is expected to exist solely as a vapor in the ambient atmosphere. Vapor-phase 4-methyl-2-pentyl acetate is degraded in the atmosphere by reaction with photochemically-produced hydroxyl radicals(SRC); the half-life for this reaction in air is estimated to be about 2.0 days(3,SRC). Source: Hazardous Substances Data Bank (HSDB)
- Sources/Uses: Used as a lacquer solvent and fragrance; [ACGIH] Source: Haz-Map, Information on Hazardous Chemicals and Occupational Diseases
- Industrial Processes with risk of exposure: Painting (Solvents) [Category: Paint] Source: Haz-Map, Information on Hazardous Chemicals and Occupational Diseases
- Uses: AS FRAGRANCES IN THE PERFUME AND COSMETICS INDUSTRY, AS COMPONENTS FOR HOUSEFLY INSECTICIDES, AND AS CHEMICAL COMPONENTS FOR THE LARGE SPRUCE BARK BEETLE ATTRACTANT. /HEXYL ACETATES/ Source: Hazardous Substances Data Bank (HSDB)
- Uses: HEXYL ACETATES HAVE BEEN GRANTED GRAS STATUS BY FDA FOR FOOD USE. /HEXYL ACETATES/ Source: Hazardous Substances Data Bank (HSDB)
- Uses: Solvent for nitrocellulose and other lacquers. Source: Hazardous Substances Data Bank (HSDB)
Mapped by: Existing checksum-valid CAS to unique PubChem CID match. Retrieved: 2026-08-31. Open source record
Scientific classifications and hazard annotations provide context and do not replace the market-specific regulatory decision shown above.
Additional source coverage and match status
| Source | Result | Checked |
|---|---|---|
| NIH PubChem PUG-View | Exact match | 2026-08-31 |
A recorded no-match is useful evidence that the source was checked; it is not a claim that the substance does not exist elsewhere.
Retrieved from NIH PubChem on 2026-08-31 by checksum-valid CAS matching. Chemical properties do not replace the regulatory decision on this page.
Inventory details for DIMETHYLBUTYL ACETATE
INCI name
DIMETHYLBUTYL ACETATE
Description
1,3-Dimethylbutyl acetate
Record provenance
- Inventory reference
- 39600
- Imported identity
- DIMETHYLBUTYL ACETATE
- Source update
- 02/03/2011
Annex records for DIMETHYLBUTYL ACETATE
Key data
Related inventory evidence
Ingredients with overlapping formulation functions
Additional official and scientific sources
11 external databases to check this identity in
Each link searches that source for this identity. What each source is, and its legal weight
ECHA CHEM / Information on chemicalsPubChem PUG RESTEU Safety Gate cosmetic product alertsECHA CHEMUS EPA CompToxCosmetic Ingredient Review safety assessmentsFDA Global Substance Registration SystemILO/WHO International Chemical Safety CardsJapan NITE-CHRIPNIOSH Pocket Guide to Chemical HazardsOECD eChemPortal
How DIMETHYLBUTYL ACETATE appears in the CosIng inventory
The CosIng inventory lists DIMETHYLBUTYL ACETATE as a cosmetic ingredient and this page links it to 0 annex records. The inventory entry captures names and identifiers, while the annex records show where the substance is prohibited, restricted or positively listed in EU cosmetics law.
DIMETHYLBUTYL ACETATE is also tagged with 1 cosmetic function in the official data. Function labels describe intended use, but they do not replace regulatory review of linked annex records before formulation or labelling work.
Frequently asked questions
DIMETHYLBUTYL ACETATE is listed in the EU CosIng ingredient inventory with no direct annex restriction records linked at this time. Absence of an annex link does not guarantee unrestricted use — always verify against the current official CosIng database before formulating.
According to the EU CosIng inventory, DIMETHYLBUTYL ACETATE carries the following function designation(s):
CAS 108-84-9 may appear across multiple EU annex records. Viewing the CAS lookup page shows all Annex II–VI entries sharing this identifier, which is useful for identifying cross-annex regulatory status of the same chemical substance.
Use the INCI Checker to screen a full ingredient list across selected markets, or compare this substance across all supported market datasets.
Source note for DIMETHYLBUTYL ACETATE
This page reproduces the CosIng inventory entry for DIMETHYLBUTYL ACETATE from public European Commission cosmetic ingredient materials and shows linked identifiers even when no direct annex match is currently attached.
Use this inventory page to research DIMETHYLBUTYL ACETATE and compare linked records, but verify restrictions and legal status against the current official source text and law before making regulatory decisions.
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