What does the restriction note for ZINC GLUCOHEPTONATE mean?

The restriction field for ZINC GLUCOHEPTONATE reads: III/24. This is the restriction note from the CosIng inventory. For authoritative conditions and limits, always refer to the linked annex entries.

What other records share CAS 12565-63-8?

CAS 12565-63-8 may appear across multiple EU annex records. The CAS lookup page shows all Annex II–VI entries sharing this identifier, useful for identifying cross-annex regulatory status of the same chemical substance.

How do I check if my formula contains ZINC GLUCOHEPTONATE?

Use the INCI Checker to screen a full ingredient list across selected markets, or use the substance market comparison to review this identity across all supported market datasets.

InventoryRef 3896015/10/2010

ZINC GLUCOHEPTONATE

Zinc, bis [(2.xi.)-D-gluco-heptonato]-

ZINC GLUCOHEPTONATE is linked to 1 EU annex record on this page. Inventory note: III/24.

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Regulatory evidence by market

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Market	Evidence status	Records	Source language
European Union	Evidence linked Restricted entry found Open this evidence	1	English and EU languages
Great Britain	Source mapped Official source mapped; ingredient rule not imported	0	English
Canada	Source mapped Official source mapped; ingredient rule not imported	0	English and French
New Zealand	Source mapped Official source mapped; ingredient rule not imported	0	English
ASEAN	Source mapped Official source mapped; ingredient rule not imported	0	English and national languages
China	Source mapped Official source mapped; ingredient rule not imported	0	Chinese with selected English material
Japan	Source mapped Official source mapped; ingredient rule not imported	0	Japanese; official English translation available
South Korea	Source mapped Official source mapped; ingredient rule not imported	0	Korean with some English names
United States	Source mapped Official source mapped; ingredient rule not imported	0	English
Australia	Source mapped Official source mapped; ingredient rule not imported	0	English
Brazil	Source mapped Official source mapped; ingredient rule not imported	0	Portuguese with INCI crosswalks
India	Source mapped Official source mapped; ingredient rule not imported	0	English and Hindi
Saudi Arabia	Source mapped Official source mapped; ingredient rule not imported	0	Arabic and English

Chemical identity and properties

PubChem 2D chemical structure for CAS 12565-63-8

CAS 12565-63-8PubChem CID 73357728

Zinc, bis[(2xi)-D-gluco-heptonato]-

IUPAC name: zinc bis((3R,4S,5R,6R)-2,3,4,5,6,7-hexahydroxyheptanoate)

Molecular formula: C14H26O16Zn
Molecular weight: 515.7 g/mol
Exact mass: 514.051227 Da
Topological polar surface area: 323.0 Å²
Hydrogen-bond donors: 12
Hydrogen-bond acceptors: 16
Covalent units: 3
Defined stereocentres: 8

Also known as

Zinc, bis((2xi)-D-gluco-heptonato)-Zinc, bis((2.xi.)-D-gluco-heptonato)-Zinc, bis[(2.xi.)-D-gluco-heptonato]-RefChem:196087Zinc alpha-glucoheptonate

Open full PubChem record PubChem annotations 3D structure image

Evidence from additional scientific databases

NIH PubChem PUG-View

Exact identifier match73357728

Attributed physical-property, hazard, environmental and use annotations.

Note: This chemical does not meet GHS hazard criteria for 100% (6 of 6) of all reports. Source: European Chemicals Agency (ECHA)
GHS Hazard Statements: Not Classified; Reported as not meeting GHS hazard criteria by 6 of 6 companies. For more detailed information, please visit ECHA C&L website. Source: European Chemicals Agency (ECHA)
ECHA C&L Notifications Summary: Aggregated GHS information provided per 6 reports by companies from 1 notifications to the ECHA C&L Inventory.; Reported as not meeting GHS hazard criteria per 6 of 6 reports by companies.; There are 0 notifications provided by 0 of 6 reports by companies with hazard statement code(s).; Information may vary between notifications depending on impurities, additives, and other factors. The percentage value in parenthesis indicates the notified classification ratio from companies that provide hazard codes. Only hazard codes with percentage values above 10% are shown. For more detailed information, please visit ECHA C&L website. Source: European Chemicals Agency (ECHA)

Mapped by: Existing checksum-valid CAS to unique PubChem CID match. Retrieved: 2026-08-31. Open source record

Scientific classifications and hazard annotations provide context and do not replace the market-specific regulatory decision shown above.

Additional source coverage and match status

Source	Result	Checked
NIH PubChem PUG-View	Exact match	2026-08-31

A recorded no-match is useful evidence that the source was checked; it is not a claim that the substance does not exist elsewhere.

Retrieved from NIH PubChem on 2026-08-31 by checksum-valid CAS matching. Chemical properties do not replace the regulatory decision on this page.

Inventory details for ZINC GLUCOHEPTONATE

INCI name

ZINC GLUCOHEPTONATE

Description

Zinc, bis [(2.xi.)-D-gluco-heptonato]-

Record provenance

Inventory reference: 38960
Imported identity: ZINC GLUCOHEPTONATE
Source update: 15/10/2010

European Commission CosIng source notes

Annex records for ZINC GLUCOHEPTONATE

Annex III Restriction reference

Entry 24

ZINC ACETATE / ZINC CHLORIDE / ZINC GLUCONATE / ZINC GLUTAMATE

Key data

CAS

12565-63-8

—

Restriction

III/24

Function

SKIN CONDITIONING: Maintaining the skin in good condition.

Official EU ingredient-name evidence

The ingredient name exactly matches the official 2025 EU glossary of common ingredient names.

#30312 · ZINC GLUCOHEPTONATE

Ingredients with overlapping formulation functions

ZINC DNASKIN CONDITIONING

ZINC DOCOSAHEXAENOATE HYDROXIDEHAIR CONDITIONING, SKIN CONDITIONING, SKIN PROTECTING, UV ABSORBER

ZINC EICOSAPENTAENOATE HYDROXIDEHAIR CONDITIONING, SKIN CONDITIONING, SKIN PROTECTING, VISCOSITY CONTROLLING

ZINC FRUCTOSE DIPHOSPHATEANTIOXIDANT, SKIN CONDITIONING

ZINC GLUCONATEDEODORANT, SKIN CONDITIONING

ZINC GLUTAMATEDEODORANT, SKIN CONDITIONING

ZINC GLYCINATE SALICYLATEANTI-SEBORRHEIC, ANTIMICROBIAL, SKIN CONDITIONING

ZINC GLYCYRRHETINATEFRAGRANCE, SKIN CONDITIONING

Additional official and scientific sources

11 external databases to check this identity in

Each link searches that source for this identity. What each source is, and its legal weight

ECHA CHEM / Information on chemicals PubChem PUG REST EU Safety Gate cosmetic product alerts ECHA CHEM US EPA CompTox Cosmetic Ingredient Review safety assessments FDA Global Substance Registration System ILO/WHO International Chemical Safety Cards Japan NITE-CHRIP NIOSH Pocket Guide to Chemical Hazards OECD eChemPortal

How ZINC GLUCOHEPTONATE appears in the CosIng inventory

The CosIng inventory lists ZINC GLUCOHEPTONATE as a cosmetic ingredient and this page links it to 1 annex record. The inventory entry captures names and identifiers, while the annex record shows where the substance is prohibited, restricted or positively listed in EU cosmetics law.

ZINC GLUCOHEPTONATE is also tagged with 1 cosmetic function in the official data. Function labels describe intended use, but they do not replace regulatory review of linked annex records before formulation or labelling work.

Frequently asked questions

ZINC GLUCOHEPTONATE appears in the EU CosIng inventory and has linked annex records. Check the annex records above for applicable restrictions, concentration limits and conditions of use. Annex II listing means prohibited; Annex III means restricted; Annexes IV, V and VI mean permitted under specified conditions.

The restriction field for ZINC GLUCOHEPTONATE reads: "III/24". This is the restriction note recorded in the CosIng inventory for this ingredient. For authoritative conditions and limits, always refer to the linked annex entries above.

According to the EU CosIng inventory, ZINC GLUCOHEPTONATE carries the following function designation(s):

SKIN CONDITIONING

CAS 12565-63-8 may appear across multiple EU annex records. Viewing the CAS lookup page shows all Annex II–VI entries sharing this identifier, which is useful for identifying cross-annex regulatory status of the same chemical substance.

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Source note for ZINC GLUCOHEPTONATE

This page combines the CosIng inventory entry for ZINC GLUCOHEPTONATE with 1 linked Annex II–VI record from the local dataset built from public European Commission cosmetic ingredient materials.

Use this inventory page to research ZINC GLUCOHEPTONATE and compare linked records, but verify restrictions and legal status against the current official source text and law before making regulatory decisions.

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