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InventoryRef 3856215/10/2010

TETRAHYDROXYPROPYL ETHYLENEDIAMINE

1,1',1'',1'''-Ethylenedinitrilotetrapropan-2-ol

TETRAHYDROXYPROPYL ETHYLENEDIAMINE is listed in the EU CosIng inventory, but no direct annex records are linked on this page yet.

Regulatory evidence by market

No rule for this ingredient has been imported for any of the 13 markets tracked here.

That describes this inventory, not the law. No imported rule is not evidence that an ingredient is permitted: a rule may exist under another name or identifier, or in a dataset not yet imported here.

Chemical identity and properties

PubChem 2D chemical structure for CAS 102-60-3
CAS 102-60-3PubChem CID 7615

Edetol

Tetrakis(2-hydroxypropyl)ethylenediamine is an amino alcohol. ChEBI

IUPAC name
1-[2-[bis(2-hydroxypropyl)amino]ethyl-(2-hydroxypropyl)amino]propan-2-ol
Molecular formula
C14H32N2O4
Molecular weight
292.41 g/mol
Exact mass
292.23620751 Da
XLogP3
-0.7
Topological polar surface area
87.4 Ų
Hydrogen-bond donors
4
Hydrogen-bond acceptors
6
Covalent units
1
Defined stereocentres
0

Also known as

N,N,N',N'-Tetrakis(2-hydroxypropyl)ethylenediamineNeutrol TEAdeka QuadrolQuadrol L1,1',1'',1'''-(Ethylenedinitrilo)tetra-2-propanol2-Propanol, 1,1',1'',1'''-(1,2-ethanediyldinitrilo)tetrakis-Edetolum [Latin]Edetolum
16 more reported names
Edetol [USAN:INN]NSC 369219TETRAKIS(2-HYDROXYPROPYL)ETHYLENEDIAMINEHSDB 5349EINECS 203-041-4Ethylenediamine-N,N,N',N'-tetra-2-propanolUNII-Q4R969U9FRNSC-369219Edetol (USAN)BRN 1781143Neutrol TE (TN)CCRIS 8275EDETOL [HSDB]EDETOL [USAN]EDETOL [INN]2-Propanol, 1',1',1'',1'''-(1,2-ethanediyldinitrilo)tetrakis-
External database identifiers

Evidence from additional scientific databases

EMBL-EBI ChEBI
Exact identifier matchCHEBI:193592

Tetrakis(2-hydroxypropyl)ethylenediamine

Formula
C14H32N2O4
Average mass
292.420 g/mol
Monoisotopic mass
292.23621 Da
Formal charge
0
  • amino alcohol — is a (CHEBI:22478)
  • amino alcohol — is a (CHEBI:22478)
Additional curated names
1-[2-[bis(2-hydroxypropyl)amino]ethyl-(2-hydroxypropyl)amino]propan-2-ol
Cross-references from this source

Mapped by: Exact CAS cross-reference in the ChEBI compound record. Retrieved: 2026-08-31. Open source record

NIH PubChem PUG-View
Exact identifier match7615

Attributed physical-property, hazard, environmental and use annotations.

  • Note: This chemical does not meet GHS hazard criteria for 15.1% (88 of 582) of reports. Source: European Chemicals Agency (ECHA)
  • Signal: Warning Source: European Chemicals Agency (ECHA)
  • GHS Hazard Statements: H315 (10.1%): Causes skin irritation [Warning Skin corrosion/irritation]; H319 (75.6%): Causes serious eye irritation [Warning Serious eye damage/eye irritation] Source: European Chemicals Agency (ECHA)
  • Precautionary Statement Codes: P264, P264+P265, P280, P302+P352, P305+P351+P338, P321, P332+P317, P337+P317, and P362+P364 (click each P-code to see the statement) Source: European Chemicals Agency (ECHA)
  • ECHA C&L Notifications Summary: Aggregated GHS information provided per 582 reports by companies from 11 notifications to the ECHA C&L Inventory. Each notification may be associated with multiple companies.; Reported as not meeting GHS hazard criteria per 88 of 582 reports by companies.; There are 9 notifications provided by 494 of 582 reports by companies with hazard statement code(s).; Information may vary between notifications depending on impurities, additives, and other factors. The percentage value in parenthesis indicates the notified classification ratio from companies that provide hazard codes. Only hazard codes with percentage values above 10% are shown. For more detailed information, please visit ECHA C&L website. Source: European Chemicals Agency (ECHA)
  • Industry Uses: Chelating agent; Etching agent; Not Known or Reasonably Ascertainable; Plasticizer; pH regulating agent; Plating agent; Monomers; Other; Solvent Source: EPA Chemical Data Reporting (CDR)

Mapped by: Existing checksum-valid CAS to unique PubChem CID match. Retrieved: 2026-08-31. Open source record

Scientific classifications and hazard annotations provide context and do not replace the market-specific regulatory decision shown above.

Additional source coverage and match status
SourceResultChecked
EMBL-EBI ChEBIExact match2026-08-31
NIH PubChem PUG-ViewExact match2026-08-31

A recorded no-match is useful evidence that the source was checked; it is not a claim that the substance does not exist elsewhere.

Retrieved from NIH PubChem on 2026-08-31 by checksum-valid CAS matching. Chemical properties do not replace the regulatory decision on this page.

Inventory details for TETRAHYDROXYPROPYL ETHYLENEDIAMINE

INCI name

TETRAHYDROXYPROPYL ETHYLENEDIAMINE

INN name

edetol

Description

1,1',1'',1'''-Ethylenedinitrilotetrapropan-2-ol

Record provenance

Inventory reference
38562
Imported identity
TETRAHYDROXYPROPYL ETHYLENEDIAMINE
Source update
15/10/2010
European Commission CosIng source notes

Key data

Restriction
Function
CHELATING
Forming complexes with metal ions which could affect the stability and/or appearance of cosmetics.

Official EU ingredient-name evidence

The ingredient name exactly matches the official 2025 EU glossary of common ingredient names.

Ingredients with overlapping formulation functions

Additional official and scientific sources

11 external databases to check this identity in

How TETRAHYDROXYPROPYL ETHYLENEDIAMINE appears in the CosIng inventory

The CosIng inventory lists TETRAHYDROXYPROPYL ETHYLENEDIAMINE as a cosmetic ingredient and this page links it to 0 annex records. The inventory entry captures names and identifiers, while the annex records show where the substance is prohibited, restricted or positively listed in EU cosmetics law.

TETRAHYDROXYPROPYL ETHYLENEDIAMINE is also tagged with 1 cosmetic function in the official data. Function labels describe intended use, but they do not replace regulatory review of linked annex records before formulation or labelling work.

Frequently asked questions

TETRAHYDROXYPROPYL ETHYLENEDIAMINE is listed in the EU CosIng ingredient inventory with no direct annex restriction records linked at this time. Absence of an annex link does not guarantee unrestricted use — always verify against the current official CosIng database before formulating.

According to the EU CosIng inventory, TETRAHYDROXYPROPYL ETHYLENEDIAMINE carries the following function designation(s):

CAS 102-60-3 may appear across multiple EU annex records. Viewing the CAS lookup page shows all Annex II–VI entries sharing this identifier, which is useful for identifying cross-annex regulatory status of the same chemical substance.

Use the INCI Checker to screen a full ingredient list across selected markets, or compare this substance across all supported market datasets.

Source note for TETRAHYDROXYPROPYL ETHYLENEDIAMINE

This page reproduces the CosIng inventory entry for TETRAHYDROXYPROPYL ETHYLENEDIAMINE from public European Commission cosmetic ingredient materials and shows linked identifiers even when no direct annex match is currently attached.

Use this inventory page to research TETRAHYDROXYPROPYL ETHYLENEDIAMINE and compare linked records, but verify restrictions and legal status against the current official source text and law before making regulatory decisions.

Tools & next steps

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