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CAS 105883-43-0 may appear across multiple EU annex records. The CAS lookup page shows all Annex II–VI entries sharing this identifier, useful for identifying cross-annex regulatory status of the same chemical substance.

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InventoryRef 3534415/10/2010

METHYLSILANOL ACETYLMETHIONATE

L-Methionine, N-acetyl-, dihydroxymethylsilyl ester

METHYLSILANOL ACETYLMETHIONATE is listed in the EU CosIng inventory, but no direct annex records are linked on this page yet.

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Regulatory evidence by market

No rule for this ingredient has been imported for any of the 13 markets tracked here.

That describes this inventory, not the law. No imported rule is not evidence that an ingredient is permitted: a rule may exist under another name or identifier, or in a dataset not yet imported here.

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Chemical identity and properties

PubChem 2D chemical structure for CAS 105883-43-0

CAS 105883-43-0PubChem CID 71587401

Methylsilanol acetylmethionate

IUPAC name: [dihydroxy(methyl)silyl] (2S)-2-acetamido-4-methylsulfanylbutanoate

Molecular formula: C8H17NO5SSi
Molecular weight: 267.38 g/mol
Exact mass: 267.05967035 Da
Topological polar surface area: 121.0 Å²
Hydrogen-bond donors: 3
Hydrogen-bond acceptors: 6
Covalent units: 1
Defined stereocentres: 1

Also known as

FKT0KP5RFCUNII-FKT0KP5RFCL-Methionine, N-acetyl-, dihydroxymethylsilyl esterDIHYDROXYMETHYLSILYL N-ACETYLMETHIONATERefChem:158310METHYLSILANOL ACETYLMETHIONATE [INCI]Dihydroxy(methyl)silyl N-acetyl-L-methioninate

Open full PubChem record PubChem annotations 3D structure image

External database identifiers

EPA DTXSID:DTXSID80147381

Evidence from additional scientific databases

NIH PubChem PUG-View

Exact identifier match71587401

Attributed physical-property, hazard, environmental and use annotations.

Mapped by: Existing checksum-valid CAS to unique PubChem CID match. Retrieved: 2026-08-31. Open source record

Scientific classifications and hazard annotations provide context and do not replace the market-specific regulatory decision shown above.

Additional source coverage and match status

Source	Result	Checked
EMBL-EBI ChEBI	No exact record	2026-08-31
NIH PubChem PUG-View	Exact match	2026-08-31

A recorded no-match is useful evidence that the source was checked; it is not a claim that the substance does not exist elsewhere.

Retrieved from NIH PubChem on 2026-08-31 by checksum-valid CAS matching. Chemical properties do not replace the regulatory decision on this page.

Inventory details for METHYLSILANOL ACETYLMETHIONATE

INCI name

METHYLSILANOL ACETYLMETHIONATE

Description

L-Methionine, N-acetyl-, dihydroxymethylsilyl ester

Record provenance

Inventory reference: 35344
Imported identity: METHYLSILANOL ACETYLMETHIONATE
Source update: 15/10/2010

European Commission CosIng source notes

Annex records for METHYLSILANOL ACETYLMETHIONATE

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Key data

CAS

105883-43-0

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Restriction

—

Function

ANTISTATIC: Preventing and/or reducing static electricity by neutralising electrical charge on surfaces.
HAIR CONDITIONING: Enhancing the appearance and feel of hair. Leaving the hair easy to comb, supple, soft and shiny and/or imparting volume, lightness, gloss, texture, etc.
SKIN CONDITIONING: Maintaining the skin in good condition.

Official EU ingredient-name evidence

The ingredient name exactly matches the official 2025 EU glossary of common ingredient names.

#16659 · METHYLSILANOL ACETYLMETHIONATE

Ingredients with overlapping formulation functions

METHYL HYDROXYCETYL GLUCAMINIUM LACTATEANTISTATIC, HAIR CONDITIONING, SKIN CONDITIONING

METHYL HYDROXYMETHYL OLEYL OXAZOLINEANTISTATIC, HAIR CONDITIONING

METHYLBENZETHONIUM CHLORIDEANTIMICROBIAL, ANTISTATIC, DEODORANT, SURFACTANT - CLEANSING

METHYLENEBIS TALLOW ACETAMIDODIMONIUM CHLORIDEANTISTATIC

METHYLSILANOL ACETYLTYROSINEANTISTATIC, SKIN CONDITIONING

METHYLSILANOL ELASTINATEANTISTATIC, SKIN CONDITIONING

METHYLSILANOL HYDROXYPROLINEANTISTATIC, SKIN CONDITIONING

METHYLSILANOL HYDROXYPROLINE ASPARTATEANTISTATIC, SKIN CONDITIONING

Additional official and scientific sources

11 external databases to check this identity in

Each link searches that source for this identity. What each source is, and its legal weight

ECHA CHEM / Information on chemicals PubChem PUG REST EU Safety Gate cosmetic product alerts ECHA CHEM US EPA CompTox Cosmetic Ingredient Review safety assessments FDA Global Substance Registration System ILO/WHO International Chemical Safety Cards Japan NITE-CHRIP NIOSH Pocket Guide to Chemical Hazards OECD eChemPortal

How METHYLSILANOL ACETYLMETHIONATE appears in the CosIng inventory

The CosIng inventory lists METHYLSILANOL ACETYLMETHIONATE as a cosmetic ingredient and this page links it to 0 annex records. The inventory entry captures names and identifiers, while the annex records show where the substance is prohibited, restricted or positively listed in EU cosmetics law.

METHYLSILANOL ACETYLMETHIONATE is also tagged with 3 cosmetic functions in the official data. Function labels describe intended use, but they do not replace regulatory review of linked annex records before formulation or labelling work.

Frequently asked questions

METHYLSILANOL ACETYLMETHIONATE is listed in the EU CosIng ingredient inventory with no direct annex restriction records linked at this time. Absence of an annex link does not guarantee unrestricted use — always verify against the current official CosIng database before formulating.

According to the EU CosIng inventory, METHYLSILANOL ACETYLMETHIONATE carries the following function designation(s):

CAS 105883-43-0 may appear across multiple EU annex records. Viewing the CAS lookup page shows all Annex II–VI entries sharing this identifier, which is useful for identifying cross-annex regulatory status of the same chemical substance.

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Source note for METHYLSILANOL ACETYLMETHIONATE

This page reproduces the CosIng inventory entry for METHYLSILANOL ACETYLMETHIONATE from public European Commission cosmetic ingredient materials and shows linked identifiers even when no direct annex match is currently attached.

Use this inventory page to research METHYLSILANOL ACETYLMETHIONATE and compare linked records, but verify restrictions and legal status against the current official source text and law before making regulatory decisions.

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Tools & next steps

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