METHYL GLYCYRRHIZATE
alpha-d-Glucopyranosiduronic acid, (3beta,20beta)-20-carboxy-11-oxo-30-norolean-12-en-3-yl 2-o-beta-d-glucopyranuronosyl-, methyl ester; Glycyrrhizic acid methyl ester
METHYL GLYCYRRHIZATE is listed in the EU CosIng inventory, but no direct annex records are linked on this page yet.
Regulatory evidence by market
No rule for this ingredient has been imported for any of the 13 markets tracked here.
That describes this inventory, not the law. No imported rule is not evidence that an ingredient is permitted: a rule may exist under another name or identifier, or in a dataset not yet imported here.
Chemical identity and properties
Glycyrrhizic acid methyl ester
- IUPAC name
- (2S,3S,4S,5R,6R)-6-[(2S,3R,4S,5S,6S)-2-[[(3S,4aR,6aR,6bS,8aS,11S,12aR,14aR,14bS)-11-methoxycarbonyl-4,4,6a,6b,8a,11,14b-heptamethyl-14-oxo-2,3,4a,5,6,7,8,9,10,12,12a,14a-dodecahydro-1H-picen-3-yl]oxy]-6-carboxylato-4,5-dihydroxyoxan-3-yl]oxy-3,4,5-trihydroxyoxane-2-carboxylate
- Molecular formula
- C43H62O16-2
- Molecular weight
- 834.9 g/mol
- Exact mass
- 834.40378589 Da
- XLogP3
- 5.4
- Topological polar surface area
- 262.0 Ų
- Hydrogen-bond donors
- 5
- Hydrogen-bond acceptors
- 16
- Covalent units
- 1
- Defined stereocentres
- 19
Also known as
External database identifiers
- EPA DTXSID:DTXSID801021582
Evidence from additional scientific databases
NIH PubChem PUG-View
Attributed physical-property, hazard, environmental and use annotations.
- Cosmetic Ingredient Review Finding(s): Safe in the present practices of use and concentration. Ingredient, concentration, and use information are available in documents discoverable at https://cir-reports.cir-safety.org Source: Cosmetic Ingredient Review (CIR)
- Cosmetic Ingredient Review Link: CIR ingredient: Methyl Glycyrrhizate Source: Cosmetic Ingredient Review (CIR)
Mapped by: Existing checksum-valid CAS to unique PubChem CID match. Retrieved: 2026-08-31. Open source record
Scientific classifications and hazard annotations provide context and do not replace the market-specific regulatory decision shown above.
Additional source coverage and match status
| Source | Result | Checked |
|---|---|---|
| EMBL-EBI ChEBI | No exact record | 2026-08-31 |
| NIH PubChem PUG-View | Exact match | 2026-08-31 |
A recorded no-match is useful evidence that the source was checked; it is not a claim that the substance does not exist elsewhere.
Retrieved from NIH PubChem on 2026-08-31 by checksum-valid CAS matching. Chemical properties do not replace the regulatory decision on this page.
Inventory details for METHYL GLYCYRRHIZATE
INCI name
METHYL GLYCYRRHIZATE
Description
alpha-d-Glucopyranosiduronic acid, (3beta,20beta)-20-carboxy-11-oxo-30-norolean-12-en-3-yl 2-o-beta-d-glucopyranuronosyl-, methyl ester; Glycyrrhizic acid methyl ester
Record provenance
- Inventory reference
- 35303
- Imported identity
- METHYL GLYCYRRHIZATE
- Source update
- 15/10/2010
Annex records for METHYL GLYCYRRHIZATE
Key data
- FRAGRANCE
- Imparting an odour or taste. Creating a perceivable pleasant smell and/or masking a bad smell.
Official EU ingredient-name evidence
The ingredient name exactly matches the official 2025 EU glossary of common ingredient names.
Related inventory evidence
Ingredients with overlapping formulation functions
Additional official and scientific sources
11 external databases to check this identity in
Each link searches that source for this identity. What each source is, and its legal weight
How METHYL GLYCYRRHIZATE appears in the CosIng inventory
The CosIng inventory lists METHYL GLYCYRRHIZATE as a cosmetic ingredient and this page links it to 0 annex records. The inventory entry captures names and identifiers, while the annex records show where the substance is prohibited, restricted or positively listed in EU cosmetics law.
METHYL GLYCYRRHIZATE is also tagged with 1 cosmetic function in the official data. Function labels describe intended use, but they do not replace regulatory review of linked annex records before formulation or labelling work.
Frequently asked questions
Source note for METHYL GLYCYRRHIZATE
This page reproduces the CosIng inventory entry for METHYL GLYCYRRHIZATE from public European Commission cosmetic ingredient materials and shows linked identifiers even when no direct annex match is currently attached.
Use this inventory page to research METHYL GLYCYRRHIZATE and compare linked records, but verify restrictions and legal status against the current official source text and law before making regulatory decisions.
Tools & next steps
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