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CAS 6384-92-5 may appear across multiple EU annex records. The CAS lookup page shows all Annex II–VI entries sharing this identifier, useful for identifying cross-annex regulatory status of the same chemical substance.

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InventoryRef 3527715/10/2010

METHYL ASPARTIC ACID

Aspartic acid, N-methyl-

METHYL ASPARTIC ACID is listed in the EU CosIng inventory, but no direct annex records are linked on this page yet.

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Regulatory evidence by market

No rule for this ingredient has been imported for any of the 13 markets tracked here.

That describes this inventory, not the law. No imported rule is not evidence that an ingredient is permitted: a rule may exist under another name or identifier, or in a dataset not yet imported here.

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Chemical identity and properties

PubChem 2D chemical structure for CAS 6384-92-5

CAS 6384-92-5PubChem CID 22880

Nmda

N-methyl-D-aspartic acid is an aspartic acid derivative having an N-methyl substituent and D-configuration. It has a role as a neurotransmitter agent. It is a D-alpha-amino acid, an amino dicarboxylic acid, a secondary amino compound and a D-aspartic acid derivative. — ChEBI

IUPAC name: (2R)-2-(methylamino)butanedioic acid

Molecular formula: C5H9NO4
Molecular weight: 147.13 g/mol
Exact mass: 147.05315777 Da
XLogP3: -3.4
Topological polar surface area: 86.6 Å²
Hydrogen-bond donors: 3
Hydrogen-bond acceptors: 5
Covalent units: 1
Defined stereocentres: 1

Also known as

N-methyl-D-aspartic acidD-Aspartic acid, N-methyl-Methyl aspartic acidN-Methyl aspartic acid2-Methylamino-succinic acidCHEBI:318821903B9Q6PIRefChem:1092483

16 more reported names

N-Methyl-D-aspartateN-Methylaspartate(R)-2-(Methylamino)succinic acidn-methyl-d-aspartic acid (nmda)N-Me-D-Asp-OH(R)-2-Ethylbutannedioic acidUNII-1903B9Q6PIMe-D-Asp-OHmethyl-d-aspartic acidN-Methyl-D-asparaginic AcidKBio2_007072NINDS_000392Tox21_500775NMDA (N-Methyl-D-aspartic acid)SR-01000597701-1BRN 1724431

Open full PubChem record PubChem annotations 3D structure image

External database identifiers

ChEBI:CHEBI:31882
ChEMBL:CHEMBL291278
EPA DTXSID:DTXSID8041082
PubMed:38219984
PubMed:35257817
PubMed:34748853
PubMed:34536444
PubMed:34389372
PubMed:31969611
PubMed:31945382
PubMed:31892740
PubMed:31787870
PubMed:30633929
PubMed:26065936
PubMed:23345247

Retrieved from NIH PubChem on 2026-08-31 by checksum-valid CAS matching. Chemical properties do not replace the regulatory decision on this page.

Inventory details for METHYL ASPARTIC ACID

INCI name

METHYL ASPARTIC ACID

Description

Aspartic acid, N-methyl-

Record provenance

Inventory reference: 35277
Imported identity: METHYL ASPARTIC ACID
Source update: 15/10/2010

European Commission CosIng source notes

Annex records for METHYL ASPARTIC ACID

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Key data

CAS

6384-92-5

—

Restriction

—

Function

ANTISTATIC: Preventing and/or reducing static electricity by neutralising electrical charge on surfaces.
HAIR CONDITIONING: Enhancing the appearance and feel of hair. Leaving the hair easy to comb, supple, soft and shiny and/or imparting volume, lightness, gloss, texture, etc.
SKIN CONDITIONING: Maintaining the skin in good condition.

Official EU ingredient-name evidence

The ingredient name exactly matches the official 2025 EU glossary of common ingredient names.

#16467 · METHYL ASPARTIC ACID

Ingredients with overlapping formulation functions

METHACRYLOYL HYDROLYZED PEA PROTEINANTISTATIC, BINDING, FILM FORMING, HAIR CONDITIONING

METHENAMMONIUM CHLORIDEANTISTATIC

METHICONEANTISTATIC, SKIN CONDITIONING, SKIN CONDITIONING - EMOLLIENT

METHIONINEANTISTATIC, HAIR CONDITIONING, SKIN CONDITIONING

METHYL DICOCAMINEANTISTATIC

METHYL GLUTAMIC ACIDANTISTATIC, HAIR CONDITIONING, SKIN CONDITIONING

METHYL HYDROXYCETYL GLUCAMINIUM LACTATEANTISTATIC, HAIR CONDITIONING, SKIN CONDITIONING

METHYL HYDROXYMETHYL OLEYL OXAZOLINEANTISTATIC, HAIR CONDITIONING

Additional official and scientific sources

11 external databases to check this identity in

Each link searches that source for this identity. What each source is, and its legal weight

ECHA CHEM / Information on chemicals PubChem PUG REST EU Safety Gate cosmetic product alerts ECHA CHEM US EPA CompTox Cosmetic Ingredient Review safety assessments FDA Global Substance Registration System ILO/WHO International Chemical Safety Cards Japan NITE-CHRIP NIOSH Pocket Guide to Chemical Hazards OECD eChemPortal

How METHYL ASPARTIC ACID appears in the CosIng inventory

The CosIng inventory lists METHYL ASPARTIC ACID as a cosmetic ingredient and this page links it to 0 annex records. The inventory entry captures names and identifiers, while the annex records show where the substance is prohibited, restricted or positively listed in EU cosmetics law.

METHYL ASPARTIC ACID is also tagged with 3 cosmetic functions in the official data. Function labels describe intended use, but they do not replace regulatory review of linked annex records before formulation or labelling work.

Frequently asked questions

METHYL ASPARTIC ACID is listed in the EU CosIng ingredient inventory with no direct annex restriction records linked at this time. Absence of an annex link does not guarantee unrestricted use — always verify against the current official CosIng database before formulating.

According to the EU CosIng inventory, METHYL ASPARTIC ACID carries the following function designation(s):

CAS 6384-92-5 may appear across multiple EU annex records. Viewing the CAS lookup page shows all Annex II–VI entries sharing this identifier, which is useful for identifying cross-annex regulatory status of the same chemical substance.

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Source note for METHYL ASPARTIC ACID

This page reproduces the CosIng inventory entry for METHYL ASPARTIC ACID from public European Commission cosmetic ingredient materials and shows linked identifiers even when no direct annex match is currently attached.

Use this inventory page to research METHYL ASPARTIC ACID and compare linked records, but verify restrictions and legal status against the current official source text and law before making regulatory decisions.

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