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InventoryRef 3520315/10/2010

MELANIN

Melanins

MELANIN is listed in the EU CosIng inventory, but no direct annex records are linked on this page yet.

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Regulatory evidence by market

No rule for this ingredient has been imported for any of the 13 markets tracked here.

That describes this inventory, not the law. No imported rule is not evidence that an ingredient is permitted: a rule may exist under another name or identifier, or in a dataset not yet imported here.

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Chemical identity and properties

PubChem 2D chemical structure for CAS 8049-97-6
CAS 8049-97-6PubChem CID 6325610

Melanins

Melanin is a member of melanins. — ChEBI

IUPAC name
6,14-dimethyl-4,12-diazapentacyclo[8.6.1.12,5.013,17.09,18]octadeca-1(17),2,5,9(18),10,13-hexaene-7,8,15,16-tetrone
Molecular formula
C18H10N2O4
Molecular weight
318.3 g/mol
Exact mass
318.06405680 Da
XLogP3
-1.2
Topological polar surface area
92.3 Ų
Hydrogen-bond donors
2
Hydrogen-bond acceptors
6
Covalent units
1
Defined stereocentres
0

Also known as

Melanin6,14-dimethyl-4,12-diazapentacyclo[8.6.1.1^{2,5}.0^{13,17}.0^{9,18}]octadeca-1(17),2,5,9(18),10,13-hexaene-7,8,15,16-tetrone6,14-dimethyl-4,12-diazapentacyclo(8.6.1.12,5.013,17.09,18)octadeca-1(17),2,5,9(18),10,13-hexaene-7,8,15,16-tetrone6,14-dimethyl-4,12-diazapentacyclo(8.6.1.1^(2,5).0^(13,17).0^(9,18))octadeca-1(17),2,5,9(18),10,13-hexaene-7,8,15,16-tetroneRefChem:156300CHEBI:25179232-473-6Melanin from Sepia officinalis
16 more reported names
PhaeomelaninsMelanin synthetic3,8-dimethylbenzo[1,2,3-cd:4,5,6-c'd']diindole-4,5,9,10(2H,7H)-tetraoneC18H10N2O4Melanin, syntheticLevodopa Impurity 15Creanatural Sepia MelaninT6T74PN7VHGTPL5415CHEBI:89634Melanin - fungal (Ganoderma lucidum)Melanin - insect (Hermetia illucens)Melanin - plant (Osmanthus fragrans)AS-881102,7-Dihydro-3,8-dimethylanthra[1,9-bc:5,10-b'c']dipyrrole-4,5,9,10-tetrone3,8-Dimethyl-2,7-dihydrobenzo[1,2,3-cd:4,5,6-c'd']diindole-4,5,9,10-tetrone
Open full PubChem recordPubChem annotations3D structure image
External database identifiers

Retrieved from NIH PubChem on 2026-08-31 by checksum-valid CAS matching. Chemical properties do not replace the regulatory decision on this page.

Inventory details for MELANIN

INCI name

MELANIN

Description

Melanins

Record provenance

Inventory reference
35203
Imported identity
MELANIN
Source update
15/10/2010
European Commission CosIng source notes
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Key data

CAS
8049-97-6
EC
232-473-6
Restriction
—
Function
SKIN PROTECTING
Helping to avoid harmful effects to the skin from external factors.

Official EU ingredient-name evidence

The ingredient name exactly matches the official 2025 EU glossary of common ingredient names.

#16138 · MELANIN

Ingredients with overlapping formulation functions

MATTHIOLA INCANA CALLUS CULTURE EXTRACTANTIOXIDANT, HAIR CONDITIONING, HUMECTANT, SKIN CONDITIONING, SKIN PROTECTING
MAULOUTCHIA HUMBLOTII SEED BUTTERANTIMICROBIAL, HAIR CONDITIONING, HUMECTANT, SKIN CONDITIONING, SKIN PROTECTING
MAYAMAEA PERMITIS EXTRACTANTIOXIDANT, SKIN CONDITIONING, SKIN PROTECTING
MEADOWFOAMAMIDOPROPYL BETAINEHUMECTANT, SKIN PROTECTING
MELIA AZADIRACHTA BARK EXTRACTANTIMICROBIAL, SKIN PROTECTING
MELIA AZADIRACHTA BRANCH/LEAF EXTRACTSKIN PROTECTING
MELICOPE ELLERYANA LEAF EXTRACTANTIOXIDANT, SKIN PROTECTING
MELICOPE HAYESII LEAF EXTRACTANTIOXIDANT, SKIN PROTECTING

Additional official and scientific sources

11 external databases to check this identity in

Each link searches that source for this identity. What each source is, and its legal weight

ECHA CHEM / Information on chemicalsPubChem PUG RESTEU Safety Gate cosmetic product alertsECHA CHEMUS EPA CompToxCosmetic Ingredient Review safety assessmentsFDA Global Substance Registration SystemILO/WHO International Chemical Safety CardsJapan NITE-CHRIPNIOSH Pocket Guide to Chemical HazardsOECD eChemPortal

How MELANIN appears in the CosIng inventory

The CosIng inventory lists MELANIN as a cosmetic ingredient and this page links it to 0 annex records. The inventory entry captures names and identifiers, while the annex records show where the substance is prohibited, restricted or positively listed in EU cosmetics law.

MELANIN is also tagged with 1 cosmetic function in the official data. Function labels describe intended use, but they do not replace regulatory review of linked annex records before formulation or labelling work.

Frequently asked questions

MELANIN is listed in the EU CosIng ingredient inventory with no direct annex restriction records linked at this time. Absence of an annex link does not guarantee unrestricted use — always verify against the current official CosIng database before formulating.

According to the EU CosIng inventory, MELANIN carries the following function designation(s):

CAS 8049-97-6 may appear across multiple EU annex records. Viewing the CAS lookup page shows all Annex II–VI entries sharing this identifier, which is useful for identifying cross-annex regulatory status of the same chemical substance.
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Source note for MELANIN

This page reproduces the CosIng inventory entry for MELANIN from public European Commission cosmetic ingredient materials and shows linked identifiers even when no direct annex match is currently attached.

Use this inventory page to research MELANIN and compare linked records, but verify restrictions and legal status against the current official source text and law before making regulatory decisions.

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