LEUCINE
L-Leucine
LEUCINE is listed in the EU CosIng inventory, but no direct annex records are linked on this page yet.
Regulatory evidence by market
No rule for this ingredient has been imported for any of the 13 markets tracked here.
That describes this inventory, not the law. No imported rule is not evidence that an ingredient is permitted: a rule may exist under another name or identifier, or in a dataset not yet imported here.
Chemical identity and properties
L-Leucine
L-leucine is the L-enantiomer of leucine. It has a role as a mouse metabolite, a Saccharomyces cerevisiae metabolite, a plant metabolite, an Escherichia coli metabolite, a human metabolite and an algal metabolite. It is a L-alpha-amino acid, a leucine, a pyruvate family amino acid and a proteinogenic amino acid. It is a conjugate base of a L-leucinium. It is a conjugate acid of a L-leucinate. It is an enantiomer of a D-leucine. It is a tautomer of a L-leucine zwitterion. — ChEBI
- IUPAC name
- (2S)-2-amino-4-methylpentanoic acid
- Molecular formula
- C6H13NO2
- Molecular weight
- 131.17 g/mol
- Exact mass
- 131.094628657 Da
- XLogP3
- -1.5
- Topological polar surface area
- 63.3 Ų
- Hydrogen-bond donors
- 2
- Hydrogen-bond acceptors
- 3
- Covalent units
- 1
- Defined stereocentres
- 1
Also known as
16 more reported names
External database identifiers
- ChEBI:CHEBI:15603
- ChEMBL:CHEMBL291962
- EPA DTXSID:DTXSID9023203
- PubMed:40885242
- PubMed:31676321
- PubMed:29968805
- PubMed:28786956
- PubMed:24125484
- PubMed:23125742
- PubMed:23124343
- PubMed:23113206
- PubMed:23109933
- PubMed:23108620
- PubMed:23107525
- PubMed:23107499
Retrieved from NIH PubChem on 2026-08-31 by checksum-valid CAS matching. Chemical properties do not replace the regulatory decision on this page.
Inventory details for LEUCINE
INCI name
LEUCINE
INN name
leucine
Description
L-Leucine
Record provenance
- Inventory reference
- 35003
- Imported identity
- LEUCINE
- Source update
- 15/10/2010
Annex records for LEUCINE
Key data
- ANTISTATIC
- Preventing and/or reducing static electricity by neutralising electrical charge on surfaces.
- HAIR CONDITIONING
- Enhancing the appearance and feel of hair. Leaving the hair easy to comb, supple, soft and shiny and/or imparting volume, lightness, gloss, texture, etc.
- SKIN CONDITIONING
- Maintaining the skin in good condition.
Official EU ingredient-name evidence
The ingredient name exactly matches the official 2025 EU glossary of common ingredient names.
Related inventory evidence
Ingredients with overlapping formulation functions
Additional official and scientific sources
11 external databases to check this identity in
Each link searches that source for this identity. What each source is, and its legal weight
How LEUCINE appears in the CosIng inventory
The CosIng inventory lists LEUCINE as a cosmetic ingredient and this page links it to 0 annex records. The inventory entry captures names and identifiers, while the annex records show where the substance is prohibited, restricted or positively listed in EU cosmetics law.
LEUCINE is also tagged with 3 cosmetic functions in the official data. Function labels describe intended use, but they do not replace regulatory review of linked annex records before formulation or labelling work.
Frequently asked questions
Source note for LEUCINE
This page reproduces the CosIng inventory entry for LEUCINE from public European Commission cosmetic ingredient materials and shows linked identifiers even when no direct annex match is currently attached.
Use this inventory page to research LEUCINE and compare linked records, but verify restrictions and legal status against the current official source text and law before making regulatory decisions.
Tools & next steps
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