Is ISOPENTANE safe to use in EU cosmetics?

ISOPENTANE is listed in the EU CosIng ingredient inventory with no direct annex restriction records linked at this time. Always verify against the current official CosIng database before formulating.

What other records share CAS 78-78-4?

CAS 78-78-4 may appear across multiple EU annex records. The CAS lookup page shows all Annex II–VI entries sharing this identifier, useful for identifying cross-annex regulatory status of the same chemical substance.

How do I check if my formula contains ISOPENTANE?

Use the INCI Checker to screen a full ingredient list across selected markets, or use the substance market comparison to review this identity across all supported market datasets.

InventoryRef 3467215/10/2010

ISOPENTANE

2-Methylbutane

ISOPENTANE is listed in the EU CosIng inventory, but no direct annex records are linked on this page yet.

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Regulatory evidence by market

No rule for this ingredient has been imported for any of the 13 markets tracked here.

That describes this inventory, not the law. No imported rule is not evidence that an ingredient is permitted: a rule may exist under another name or identifier, or in a dataset not yet imported here.

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Chemical identity and properties

PubChem 2D chemical structure for CAS 78-78-4

CAS 78-78-4PubChem CID 6556

Isopentane

Isopentane is an alkane that is butane substituted by a methyl group at position 2. It has a role as a refrigerant. — ChEBI

IUPAC name: 2-methylbutane

Molecular formula: C5H12
Molecular weight: 72.15 g/mol
Exact mass: 72.093900383 Da
XLogP3: 2.6
Topological polar surface area: 0.0 Å²
Hydrogen-bond donors: 0
Hydrogen-bond acceptors: 0
Covalent units: 1
Defined stereocentres: 0

Also known as

IsoamylhydrideButane, 2-methyl-iso-Pentane1,1,2-TrimethylethaneDimethylethylmethaneEthyldimethylmethanemethylbutane1,1-dimethylpropane

16 more reported names

iso-C5H12(CH3)2CH-CH2-CH3NSC-119476CHEBI:30362R-601aRefChem:59182-methylbutane;isopentane(CH3)2CHCH2CH3201-142-82-METHYLBUTANE-2-D12-methyl-butane95% isopentane99% isopentaneNSC 119476ISO PENTANEsolvent isopentane

Open full PubChem record PubChem annotations 3D structure image

External database identifiers

ChEBI:CHEBI:30362
ChEMBL:CHEMBL1797287
EPA DTXSID:DTXSID8025468
PubMed:33064461
PubMed:23125731
PubMed:23107700
PubMed:22980827
PubMed:22953166
PubMed:22783619
PubMed:22715780
PubMed:22701680
PubMed:22685584
PubMed:22685526
PubMed:22684032
PubMed:22675523

Retrieved from NIH PubChem on 2026-08-31 by checksum-valid CAS matching. Chemical properties do not replace the regulatory decision on this page.

Inventory details for ISOPENTANE

INCI name

ISOPENTANE

Description

2-Methylbutane

Record provenance

Inventory reference: 34672
Imported identity: ISOPENTANE
Source update: 15/10/2010

European Commission CosIng source notes

Annex records for ISOPENTANE

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Key data

CAS

78-78-4

201-142-8

Restriction

—

Function

PROPELLANT: Generating pressure in an aerosol pack, expelling contents when the valve is opened. Some liquefied propellants can act as solvents.
SOLVENT: Dissolving other components of cosmetics. Solvents are usually liquids (aqueous and nonaqueous).
VISCOSITY CONTROLLING: Increasing or decreasing the viscosity (thickness) of cosmetics.

Official EU ingredient-name evidence

The ingredient name exactly matches the official 2025 EU glossary of common ingredient names.

#13806 · ISOPENTANE

Ingredients with overlapping formulation functions

HYDROFLUOROCARBON 134APROPELLANT

HYDROFLUOROCARBON 152APROPELLANT

HYDROFLUOROCARBON 227EAPROPELLANT

ISOBUTANEPROPELLANT

NITROGENPROPELLANT

NITROUS OXIDEPROPELLANT

OZONIZED LINSEED OILPROPELLANT, SKIN CONDITIONING

PENTAFLUOROPROPANEFRAGRANCE, PROPELLANT, SOLVENT

Additional official and scientific sources

11 external databases to check this identity in

Each link searches that source for this identity. What each source is, and its legal weight

ECHA CHEM / Information on chemicals PubChem PUG REST EU Safety Gate cosmetic product alerts ECHA CHEM US EPA CompTox Cosmetic Ingredient Review safety assessments FDA Global Substance Registration System ILO/WHO International Chemical Safety Cards Japan NITE-CHRIP NIOSH Pocket Guide to Chemical Hazards OECD eChemPortal

How ISOPENTANE appears in the CosIng inventory

The CosIng inventory lists ISOPENTANE as a cosmetic ingredient and this page links it to 0 annex records. The inventory entry captures names and identifiers, while the annex records show where the substance is prohibited, restricted or positively listed in EU cosmetics law.

ISOPENTANE is also tagged with 3 cosmetic functions in the official data. Function labels describe intended use, but they do not replace regulatory review of linked annex records before formulation or labelling work.

Frequently asked questions

ISOPENTANE is listed in the EU CosIng ingredient inventory with no direct annex restriction records linked at this time. Absence of an annex link does not guarantee unrestricted use — always verify against the current official CosIng database before formulating.

According to the EU CosIng inventory, ISOPENTANE carries the following function designation(s):

CAS 78-78-4 may appear across multiple EU annex records. Viewing the CAS lookup page shows all Annex II–VI entries sharing this identifier, which is useful for identifying cross-annex regulatory status of the same chemical substance.

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Source note for ISOPENTANE

This page reproduces the CosIng inventory entry for ISOPENTANE from public European Commission cosmetic ingredient materials and shows linked identifiers even when no direct annex match is currently attached.

Use this inventory page to research ISOPENTANE and compare linked records, but verify restrictions and legal status against the current official source text and law before making regulatory decisions.

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Tools & next steps

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