What other records share CAS 822-89-9?

CAS 822-89-9 may appear across multiple EU annex records. The CAS lookup page shows all Annex II–VI entries sharing this identifier, useful for identifying cross-annex regulatory status of the same chemical substance.

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Use the INCI Checker to screen a full ingredient list across selected markets, or use the substance market comparison to review this identity across all supported market datasets.

InventoryRef 3455119/03/2019

HYDROXYPYRIDINONE

Q: What does the restriction note for HYDROXYPYRIDINONE mean?

The restriction field for HYDROXYPYRIDINONE reads: II/1249 (hypyridinone and its salts, when used as a substance in hair dye products). This is the restriction note from the CosIng inventory. For authoritative conditions and limits, always refer to the linked annex entries.

Hydroxyl-2-pyridone

HYDROXYPYRIDINONE is linked to 1 EU annex record on this page. Inventory note: II/1249 (hypyridinone and its salts, when used as a substance in hair dye products).

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Regulatory evidence by market

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Market	Evidence status	Records	Source language
European Union	Evidence linked Prohibited entry found Open this evidence	1	English and EU languages
Great Britain	Evidence linked Prohibited Open this evidence	1	English
Canada	Source mapped Official source mapped; ingredient rule not imported	0	English and French
New Zealand	Evidence linked Prohibited Open this evidence	1	English
ASEAN	Evidence linked Prohibited Open this evidence	1	English and national languages
China	Evidence linked Prohibited Open this evidence	1	Chinese with selected English material
Japan	Source mapped Official source mapped; ingredient rule not imported	0	Japanese; official English translation available
South Korea	Evidence linked Prohibited Open this evidence	1	Korean with some English names
United States	Source mapped Official source mapped; ingredient rule not imported	0	English
Australia	Source mapped Official source mapped; ingredient rule not imported	0	English
Brazil	Evidence linked Prohibited Open this evidence	1	Portuguese with INCI crosswalks
India	Evidence linked Prohibited Open this evidence	1	English and Hindi
Saudi Arabia	Evidence linked Prohibited Open this evidence	1	Arabic and English

Chemical identity and properties

PubChem 2D chemical structure for CAS 822-89-9

CAS 822-89-9PubChem CID 69975

Hydroxypyridinone

IUPAC name: 1-hydroxypyridin-2-one

Molecular formula: C5H5NO2
Molecular weight: 111.10 g/mol
Exact mass: 111.032028402 Da
XLogP3: -0.7
Topological polar surface area: 40.5 Å²
Hydrogen-bond donors: 1
Hydrogen-bond acceptors: 2
Covalent units: 1
Defined stereocentres: 0

Also known as

2-Pyridinol-1-oxide2-Hydroxypyridine 1-oxide1-Hydroxy-2-pyridone2-Pyridinol, 1-oxide1-hydroxy-2(1h)-pyridinone2(1H)-Pyridinone, 1-hydroxy-Hydroxyl-2-pyridoneN-hydroxy-2-pyridone

16 more reported names

N-Hydroxyl-2-pyridone1-hydroxy-2(1H)-pyridoneEINECS 212-506-0NSC-4069722-Pyridinol, N-oxideEINECS 236-100-8NSC 406972AI3-60199RefChem:7895691,2-HOPOHYDROXYPYRIDINONE [INCI]236-100-82-Hydroxypyridine-N-oxide2-Hydroxypyridine N-Oxide1-hydroxy-1,2-dihydropyridin-2-one1-hydroxypyridin-2(1H)-one

Open full PubChem record PubChem annotations 3D structure image

External database identifiers

ChEMBL:CHEMBL3898657
ChEMBL:CHEMBL81398
EPA DTXSID:DTXSID70231622
PubMed:22905650
PubMed:21472573
PubMed:21200488
PubMed:20873782
PubMed:20446312
PubMed:20410632
PubMed:19907788
PubMed:19821559
PubMed:19744810
PubMed:19722546
PubMed:19639983
PubMed:19345006

Retrieved from NIH PubChem on 2026-09-02 by checksum-valid CAS matching. Chemical properties do not replace the regulatory decision on this page.

Inventory details for HYDROXYPYRIDINONE

INCI name

HYDROXYPYRIDINONE

Description

Hydroxyl-2-pyridone

Record provenance

Inventory reference: 34551
Imported identity: HYDROXYPYRIDINONE
Source update: 19/03/2019

European Commission CosIng source notes

Annex records for HYDROXYPYRIDINONE

Annex II Restriction reference

Entry 1249

Hydroxypyridinone and its salts, when used as a substance in hair dye products

CAS: 822-89-9

EC: 212-506-0

Key data

CAS

822-89-9

212-506-0

Restriction

II/1249 (hypyridinone and its salts, when used as a substance in hair dye products)

Function

HAIR DYEING: Imparting color to hair. Hair dyeing preparations may be temporary, semi-permanent, or permanent, depending on the length of time the colorant remains on the hair.
SURFACTANT - FOAM BOOSTING: Increasing foaming capacity and/or stabilizing foams in general.

Official EU ingredient-name evidence

The ingredient name exactly matches the official 2025 EU glossary of common ingredient names.

#13406 · HYDROXYPYRIDINONE

Ingredients with overlapping formulation functions

HYDROXYETHYLAMINOMETHYL-P-AMINOPHENOL HCLHAIR DYEING

HYDROXYPROPYL BIS(N-HYDROXYETHYL-P-PHENYLENEDIAMINE) HCLHAIR DYEING

HYDROXYPROPYL-P-PHENYLENEDIAMINEHAIR DYEING

HYDROXYPROPYL-P-PHENYLENEDIAMINE HCLHAIR DYEING

INDIGOFERA TINCTORIA LEAFHAIR DYEING

ISATINHAIR DYEING

JATROPHA CURCAS LEAF POWDERHAIR DYEING

LACCAIC ACIDHAIR DYEING

Additional official and scientific sources

11 external databases to check this identity in

Each link searches that source for this identity. What each source is, and its legal weight

ECHA CHEM / Information on chemicals PubChem PUG REST EU Safety Gate cosmetic product alerts ECHA CHEM US EPA CompTox Cosmetic Ingredient Review safety assessments FDA Global Substance Registration System ILO/WHO International Chemical Safety Cards Japan NITE-CHRIP NIOSH Pocket Guide to Chemical Hazards OECD eChemPortal

How HYDROXYPYRIDINONE appears in the CosIng inventory

The CosIng inventory lists HYDROXYPYRIDINONE as a cosmetic ingredient and this page links it to 1 annex record. The inventory entry captures names and identifiers, while the annex record shows where the substance is prohibited, restricted or positively listed in EU cosmetics law.

HYDROXYPYRIDINONE is also tagged with 2 cosmetic functions in the official data. Function labels describe intended use, but they do not replace regulatory review of linked annex records before formulation or labelling work.

Frequently asked questions

HYDROXYPYRIDINONE appears in the EU CosIng inventory and has linked annex records. Check the annex records above for applicable restrictions, concentration limits and conditions of use. Annex II listing means prohibited; Annex III means restricted; Annexes IV, V and VI mean permitted under specified conditions.

The restriction field for HYDROXYPYRIDINONE reads: "II/1249 (hypyridinone and its salts, when used as a substance in hair dye products)". This is the restriction note recorded in the CosIng inventory for this ingredient. For authoritative conditions and limits, always refer to the linked annex entries above.

According to the EU CosIng inventory, HYDROXYPYRIDINONE carries the following function designation(s):

CAS 822-89-9 may appear across multiple EU annex records. Viewing the CAS lookup page shows all Annex II–VI entries sharing this identifier, which is useful for identifying cross-annex regulatory status of the same chemical substance.

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Source note for HYDROXYPYRIDINONE

This page combines the CosIng inventory entry for HYDROXYPYRIDINONE with 1 linked Annex II–VI record from the local dataset built from public European Commission cosmetic ingredient materials.

Use this inventory page to research HYDROXYPYRIDINONE and compare linked records, but verify restrictions and legal status against the current official source text and law before making regulatory decisions.

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