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InventoryRef 3429115/10/2010

HINOKITIOL

2-Hydroxy-4-isopropyl-2,4,6-cyclohepta-2,4,6-trien-1-one

HINOKITIOL is listed in the EU CosIng inventory, but no direct annex records are linked on this page yet.

Regulatory evidence by market

This matrix separates verified ingredient rules from sources that are mapped but not yet imported. No imported rule does not mean the ingredient is permitted.

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MarketEvidence statusRecordsSource language
European UnionSource mapped
Inventory entry; no linked annex rule
0English and EU languages
Great BritainSource mapped
Official source mapped; ingredient rule not imported
0English
CanadaSource mapped
Official source mapped; ingredient rule not imported
0English and French
New ZealandSource mapped
Official source mapped; ingredient rule not imported
0English
ASEANSource mapped
Official source mapped; ingredient rule not imported
0English and national languages
ChinaSource mapped
Official source mapped; ingredient rule not imported
0Chinese with selected English material
JapanEvidence linked
Restricted
Open this evidence
1Japanese; official English translation available
South KoreaSource mapped
Official source mapped; ingredient rule not imported
0Korean with some English names
United StatesSource mapped
Official source mapped; ingredient rule not imported
0English
AustraliaSource mapped
Official source mapped; ingredient rule not imported
0English
BrazilSource mapped
Official source mapped; ingredient rule not imported
0Portuguese with INCI crosswalks
IndiaSource mapped
Official source mapped; ingredient rule not imported
0English and Hindi
Saudi ArabiaSource mapped
Official source mapped; ingredient rule not imported
0Arabic and English

Chemical identity and properties

PubChem 2D chemical structure for CAS 499-44-5
CAS 499-44-5PubChem CID 3611

Hinokitiol

Beta-thujaplicin is a monoterpenoid that is cyclohepta-2,4,6-trien-1-one substituted by a hydroxy group at position 2 and an isopropyl group at position 4. Isolated from Thuja plicata and Chamaecyparis obtusa, it exhibits antimicrobial activities. It has a role as an antibacterial agent, an antineoplastic agent, an antifungal agent, an antiplasmodial drug and a plant metabolite. It is a monoterpenoid, an enol and a cyclic ketone. It derives from a hydride of a cyclohepta-1,3,5-triene. ChEBI

IUPAC name
2-hydroxy-6-propan-2-ylcyclohepta-2,4,6-trien-1-one
Molecular formula
C10H12O2
Molecular weight
164.20 g/mol
Exact mass
164.083729621 Da
XLogP3
2.1
Topological polar surface area
37.3 Ų
Hydrogen-bond donors
1
Hydrogen-bond acceptors
2
Covalent units
1
Defined stereocentres
0

Also known as

beta-Thujaplicin4-Isopropyltropolone2,4,6-Cycloheptatrien-1-one, 2-hydroxy-4-(1-methylethyl)-2-Hydroxy-4-(1-methylethyl)-2,4,6-cycloheptatrien-1-one2-hydroxy-4-(propan-2-yl)cyclohepta-2,4,6-trien-1-oneU5335D6EBINSC-18804CHEBI:10447
16 more reported names
RefChem:5679832-hydroxy-4-isopropyl-2,4,6-cycloheptatriene-1-onehydron;7-oxo-5-propan-2-ylcyclohepta-1,3,5-trien-1-olate207-880-7Hinokitolbeta-ThujaplicineIsopropyltropolone.beta.-ThujaplicinTHUJAPLICIN, BETATropolone, 4-isopropyl-beta-Isopropyltropolon2-Hydroxy-4-isopropyl-2,4,6-cycloheptatrien-1-one2-Hydroxy-4-isopropylcyclohepta-2,4,6-trien-1-onebeta-Isopropyltropolone.beta.-IsopropyltropolonNSC 18804
External database identifiers

Retrieved from NIH PubChem on 2026-09-02 by checksum-valid CAS matching. Chemical properties do not replace the regulatory decision on this page.

Inventory details for HINOKITIOL

INCI name

HINOKITIOL

Description

2-Hydroxy-4-isopropyl-2,4,6-cyclohepta-2,4,6-trien-1-one

Record provenance

Inventory reference
34291
Imported identity
HINOKITIOL
Source update
15/10/2010
European Commission CosIng source notes

Key data

Restriction
Function
ANTISTATIC
Preventing and/or reducing static electricity by neutralising electrical charge on surfaces.
HAIR CONDITIONING
Enhancing the appearance and feel of hair. Leaving the hair easy to comb, supple, soft and shiny and/or imparting volume, lightness, gloss, texture, etc.

Official EU ingredient-name evidence

The ingredient name exactly matches the official 2025 EU glossary of common ingredient names.

Ingredients with overlapping formulation functions

Additional official and scientific sources

11 external databases to check this identity in

How HINOKITIOL appears in the CosIng inventory

The CosIng inventory lists HINOKITIOL as a cosmetic ingredient and this page links it to 0 annex records. The inventory entry captures names and identifiers, while the annex records show where the substance is prohibited, restricted or positively listed in EU cosmetics law.

HINOKITIOL is also tagged with 2 cosmetic functions in the official data. Function labels describe intended use, but they do not replace regulatory review of linked annex records before formulation or labelling work.

Frequently asked questions

HINOKITIOL is listed in the EU CosIng ingredient inventory with no direct annex restriction records linked at this time. Absence of an annex link does not guarantee unrestricted use — always verify against the current official CosIng database before formulating.

According to the EU CosIng inventory, HINOKITIOL carries the following function designation(s):

CAS 499-44-5 may appear across multiple EU annex records. Viewing the CAS lookup page shows all Annex II–VI entries sharing this identifier, which is useful for identifying cross-annex regulatory status of the same chemical substance.

Use the INCI Checker to screen a full ingredient list across selected markets, or compare this substance across all supported market datasets.

Source note for HINOKITIOL

This page reproduces the CosIng inventory entry for HINOKITIOL from public European Commission cosmetic ingredient materials and shows linked identifiers even when no direct annex match is currently attached.

Use this inventory page to research HINOKITIOL and compare linked records, but verify restrictions and legal status against the current official source text and law before making regulatory decisions.

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